(114 nodes) Vitamin binding network (Verticillium dahliae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	VDAG_04886	1-aminocyclopropane-1-carboxylate synthase. (424 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (488 aa)
	VDAG_10440	MOSC domain-containing protein. (322 aa)
	VDAG_10392	1-aminocyclopropane-1-carboxylate deaminase. (345 aa)
	VDAG_10211	Carrier domain-containing protein. (2708 aa)
	VDAG_10169	Aspartate aminotransferase. (452 aa)
	VDAG_10138	Aminotransferase. (415 aa)
	VDAG_10134	Uncharacterized protein. (419 aa)
	VDAG_10018	2-oxoglutarate dehydrogenase E1. (1047 aa)
	VDAG_09970	L-serine dehydratase. (319 aa)
	VDAG_09601	Glyoxalase family protein. (143 aa)
	VDAG_09591	Serine palmitoyltransferase. (663 aa)
	VDAG_09751	L-serine dehydratase. (364 aa)
	VDAG_09549	Oxidoreductase. (294 aa)
	VDAG_09534	Aflatoxin biosynthesis polyketide synthase. (1856 aa)
	VDAG_09443	Pyruvate decarboxylase. (574 aa)
	VDAG_09420	Cystathionine gamma-synthase. (591 aa)
	VDAG_09355	8-amino-7-oxononanoate synthase. (448 aa)
	VDAG_09354	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase. (807 aa)
	VDAG_09297	O-acetylhomoserine (Thiol)-lyase. (378 aa)
	VDAG_09050	2,2-dialkylglycine decarboxylase. (286 aa)
	VDAG_09037	Cystathionine beta-lyase. (191 aa)
	VDAG_08981	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (889 aa)
	VDAG_09113	Acetolactate synthase; Belongs to the TPP enzyme family. (641 aa)
	VDAG_09093	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
	VDAG_08632	Cysteine desulfurase. (508 aa)
	VDAG_08601	Serine racemase. (376 aa)
	VDAG_08448	Lovastatin nonaketide synthase. (2210 aa)
	VDAG_08382	Phosphoserine aminotransferase. (433 aa)
	VDAG_08269	Thiamin pyrophosphokinase. (190 aa)
	VDAG_08243	UVS-3 protein. (791 aa)
	VDAG_08227	Fungal cellulose binding domain-containing protein. (301 aa)
	VDAG_08190	DUF4396 domain-containing protein. (217 aa)
	VDAG_08189	Glutamate decarboxylase. (547 aa)
	VDAG_08188	D-alanine-poly(Phosphoribitol) ligase subunit 1. (1334 aa)
	VDAG_07974	Uncharacterized protein. (377 aa)
	VDAG_07928	Lovastatin nonaketide synthase. (4042 aa)
	VDAG_07872	Acetolactate synthase. (693 aa)
	VDAG_07756	Kynurenine-oxoglutarate transaminase. (425 aa)
	VDAG_07725	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
	VDAG_07657	Uncharacterized protein. (302 aa)
	VDAG_07642	Oxidoreductase. (269 aa)
	VDAG_07270	Mycocerosic acid synthase. (2239 aa)
	VDAG_06941	Sphingosine-1-phosphate lyase. (566 aa)
	VDAG_06890	SpvB domain-containing protein. (2208 aa)
	VDAG_06729	Pyruvate decarboxylase. (547 aa)
	VDAG_06689	Serine hydroxymethyltransferase. (467 aa)
	VDAG_06675	Uncharacterized protein. (280 aa)
	VDAG_06158	Uncharacterized protein. (311 aa)
	VDAG_06136	Uncharacterized protein. (589 aa)
	VDAG_05987	Endoglucanase-4. (227 aa)
	VDAG_06397	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (502 aa)
	VDAG_06343	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (506 aa)
	VDAG_05922	Uncharacterized protein. (400 aa)
	VDAG_05908	Uncharacterized protein. (372 aa)
	VDAG_05858	Uncharacterized protein. (143 aa)
	VDAG_05743	Ornithine aminotransferase. (447 aa)
	VDAG_05633	Fatty acid synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (402 aa)
	VDAG_05632	Polyketide synthase. (307 aa)
	VDAG_05631	Carrier domain-containing protein. (177 aa)
	VDAG_05314	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase. (4757 aa)
	VDAG_05539	Uncharacterized protein. (1382 aa)
	VDAG_05538	Alanine aminotransferase. (486 aa)
	VDAG_05504	1-aminocyclopropane-1-carboxylate synthase C. (425 aa)
	VDAG_05446	Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
	VDAG_05276	Uncharacterized protein. (486 aa)
	VDAG_05021	1-aminocyclopropane-1-carboxylate synthase. (407 aa)
	VDAG_04731	Zn(2)-C6 fungal-type domain-containing protein. (724 aa)
	VDAG_04729	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (474 aa)
	VDAG_04571	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
	VDAG_04840	ACC synthase. (421 aa)
	VDAG_04198	Uncharacterized protein. (1118 aa)
	VDAG_04090	Cystathionine gamma-synthase. (591 aa)
	VDAG_04539	Lovastatin nonaketide synthase. (1113 aa)
	VDAG_04481	Aromatic amino acid aminotransferase. (562 aa)
	VDAG_04404	Cellulose-growth-specific protein. (261 aa)
	hxB	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (839 aa)
	VDAG_04041	Aminotran_1_2 domain-containing protein. (476 aa)
	VDAG_03964	Surfactin synthetase subunit 3. (1932 aa)
	VDAG_03939	O-acetylhomoserine (Thiol)-lyase. (458 aa)
	VDAG_03870	8-amino-7-oxononanoate synthase. (480 aa)
	VDAG_03697	Aminotransferase. (437 aa)
	VDAG_03696	Threonine dehydratase catabolic. (275 aa)
	VDAG_03688	Acetolactate synthase; Belongs to the TPP enzyme family. (550 aa)
	VDAG_03466	Fatty acid synthase S-acetyltransferase. (2160 aa)
	VDAG_03307	Cystathionine gamma-lyase. (420 aa)
	VDAG_03239	Methionine gamma-lyase. (449 aa)
	VDAG_02527	Uncharacterized protein. (295 aa)
	VDAG_02911	Surfactin synthetase subunit 3. (1060 aa)
	VDAG_02727	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1068 aa)
	VDAG_01999	Threonine synthase. (557 aa)
	VDAG_01983	Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (260 aa)
	VDAG_01856	Phenolpthiocerol synthesis polyketide synthase ppsA. (2402 aa)
	VDAG_01835	Fatty acid synthase S-acetyltransferase. (2623 aa)
	VDAG_01819	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (559 aa)
	VDAG_02342	Serine palmitoyltransferase. (515 aa)
	VDAG_02296	Molybdenum cofactor sulfurase. (482 aa)
	VDAG_02259	Glutamate decarboxylase. (511 aa)
	VDAG_02229	Aspartate aminotransferase. (412 aa)
	VDAG_01337	Aromatic amino acid aminotransferase. (643 aa)
	VDAG_01258	Aspartate aminotransferase. (423 aa)
	VDAG_01152	Threonine dehydratase. (581 aa)
	VDAG_01112	Aspartate aminotransferase. (394 aa)
	VDAG_00948	Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (447 aa)
	VDAG_00903	Pyruvate decarboxylase. (575 aa)
	VDAG_00824	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
	VDAG_00190	Conidial yellow pigment biosynthesis polyketide synthase. (2189 aa)
	VDAG_00186	Pyridoxal-dependent decarboxylase. (504 aa)
	VDAG_00185	Uncharacterized protein. (91 aa)
	VDAG_00184	Amino acid adenylation. (620 aa)
	VDAG_00753	BTB domain-containing protein. (272 aa)
	VDAG_00741	Uncharacterized protein. (269 aa)
	VDAG_00649	MOSC domain-containing protein. (461 aa)
	VDAG_00599	Histidinol-phosphate aminotransferase. (415 aa)

Your Current Organism:

Verticillium dahliae

NCBI taxonomy Id: 498257
Other names: V. dahliae VdLs.17, Verticillium dahliae VdLs.17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA5	VDAG_01112	G2XK42	G2WTI9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aspartate aminotransferase.	0.588
BNA5	VDAG_04041	G2XK42	G2X1B2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.514
BNA5	VDAG_04404	G2XK42	G2X280	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Cellulose-growth-specific protein.	0.427
BNA5	VDAG_04840	G2XK42	G2X355	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	ACC synthase.	0.427
BNA5	VDAG_04886	G2XK42	G2X3A1	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	1-aminocyclopropane-1-carboxylate synthase.	0.427
BNA5	VDAG_05021	G2XK42	G2X4D9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	1-aminocyclopropane-1-carboxylate synthase.	0.427
BNA5	VDAG_05504	G2XK42	G2X5J9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	1-aminocyclopropane-1-carboxylate synthase C.	0.427
BNA5	VDAG_05538	G2XK42	G2X5N3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Alanine aminotransferase.	0.427
BNA5	VDAG_05539	G2XK42	G2X5N4	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein.	0.427
BNA5	VDAG_05908	G2XK42	G2X6X6	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein.	0.427
BNA5	VDAG_05987	G2XK42	G2X846	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Endoglucanase-4.	0.427
BNA5	VDAG_06675	G2XK42	G2X943	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein.	0.427
BNA5	VDAG_07756	G2XK42	G2XC74	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynurenine-oxoglutarate transaminase.	0.957
BNA5	VDAG_08227	G2XK42	G2XDJ5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Fungal cellulose binding domain-containing protein.	0.427
BNA5	VDAG_09093	G2XK42	G2XFG9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.440
BNA5	VDAG_09601	G2XK42	G2XHV1	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Glyoxalase family protein.	0.427
BNA5	VDAG_10018	G2XK42	G2XIN6	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	2-oxoglutarate dehydrogenase E1.	0.499
VDAG_00184	VDAG_00190	G2WRK1	G2WRK7	Amino acid adenylation.	Conidial yellow pigment biosynthesis polyketide synthase.	0.642
VDAG_00184	VDAG_05633	G2WRK1	G2X651	Amino acid adenylation.	Fatty acid synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.419
VDAG_00190	VDAG_00184	G2WRK7	G2WRK1	Conidial yellow pigment biosynthesis polyketide synthase.	Amino acid adenylation.	0.642