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VDAG_06518 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (760 aa) | ||||
VDAG_06533 | Uncharacterized protein. (167 aa) | ||||
VDAG_06035 | DNA polymerase kappa. (630 aa) | ||||
VDAG_06102 | G/U mismatch-specific uracil DNA glycosylase. (313 aa) | ||||
VDAG_06114 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1755 aa) | ||||
VDAG_06654 | Intron-binding protein aquarius. (1267 aa) | ||||
VDAG_06766 | Nuc-1 negative regulatory protein preg. (433 aa) | ||||
VDAG_06842 | RNA polymerase II transcription factor B subunit 3. (353 aa) | ||||
VDAG_06864 | Uncharacterized protein. (533 aa) | ||||
VDAG_06865 | DNA repair protein rad50. (1292 aa) | ||||
VDAG_07164 | DNA-repair protein XRCC3. (459 aa) | ||||
VDAG_06914 | AKAP7_NLS domain-containing protein. (248 aa) | ||||
VDAG_06955 | Uncharacterized protein. (361 aa) | ||||
VDAG_06957 | RING-2 protein. (144 aa) | ||||
VDAG_07006 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa) | ||||
VDAG_07044 | Protein kinase domain-containing protein. (605 aa) | ||||
VDAG_07058 | Replication factor C subunit 5. (350 aa) | ||||
VDAG_07060 | Replication factor C subunit 1. (1040 aa) | ||||
VDAG_08655 | BRCT domain-containing protein. (263 aa) | ||||
VDAG_01940 | AFG2 protein. (756 aa) | ||||
VDAG_01884 | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. (2792 aa) | ||||
VDAG_01793 | DNA repair protein rad16. (955 aa) | ||||
VDAG_02255 | USP domain-containing protein; Belongs to the peptidase C19 family. (1375 aa) | ||||
VDAG_02253 | DNA mismatch repair protein msh-2; Component of the post-replicative DNA mismatch repair system (MMR). (922 aa) | ||||
VDAG_02157 | Exodeoxyribonuclease. (805 aa) | ||||
VDAG_01523 | ISWI chromatin-remodeling complex ATPase ISW2. (1119 aa) | ||||
VDAG_01358 | ATP dependent DNA ligase domain-containing protein. (981 aa) | ||||
VDAG_01245 | WD repeat-containing protein. (1034 aa) | ||||
VDAG_01192 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1211 aa) | ||||
VDAG_01189 | Fungal specific transcription factor domain-containing protein. (1005 aa) | ||||
VDAG_00994 | DNA-directed RNA polymerases I/II/III subunit 10. (76 aa) | ||||
VDAG_00986 | DNA-repair protein rad13. (1187 aa) | ||||
VDAG_00980 | ACOB protein. (276 aa) | ||||
VDAG_00976 | Serine/threonine-protein kinase chk1. (545 aa) | ||||
UNG1 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (386 aa) | ||||
VDAG_00915 | Uncharacterized protein. (130 aa) | ||||
VDAG_00914 | SprT-like domain-containing protein. (476 aa) | ||||
VDAG_00882 | PAPA-1 domain-containing protein. (149 aa) | ||||
VDAG_00879 | RMI1_N domain-containing protein. (250 aa) | ||||
VDAG_01544 | BRCT domain-containing protein. (833 aa) | ||||
VDAG_00304 | G1/S-specific cyclin pas1. (687 aa) | ||||
VDAG_00291 | FHA domain-containing protein. (764 aa) | ||||
VDAG_00265 | DNA repair and recombination protein RAD52. (532 aa) | ||||
VDAG_00235 | DNA-binding protein. (317 aa) | ||||
VDAG_00209 | DNA base excision repair N-glycosylase. (286 aa) | ||||
VDAG_00203 | Ubiquitin carboxyl-terminal hydrolase. (927 aa) | ||||
VDAG_00163 | DNA excision repair protein ERCC-8. (479 aa) | ||||
VDAG_00156 | DNA excision repair protein ERCC-6. (1061 aa) | ||||
VDAG_08535 | Ubiquitin carboxyl-terminal hydrolase; Belongs to the peptidase C19 family. (1178 aa) | ||||
VDAG_00141 | RNA polymerase II transcription factor B subunit 5. (71 aa) | ||||
VDAG_00095 | 41 kDa peptidyl-prolyl cis-trans isomerase. (386 aa) | ||||
VDAG_00787 | CPSF_A domain-containing protein. (1160 aa) | ||||
VDAG_00690 | DNA-directed RNA polymerases I. (231 aa) | ||||
VDAG_00689 | Uncharacterized protein. (486 aa) | ||||
VDAG_00585 | Uncharacterized protein. (392 aa) | ||||
VDAG_00550 | COP9 signalosome complex subunit 6. (413 aa) | ||||
VDAG_00537 | CBFD_NFYB_HMF domain-containing protein. (118 aa) | ||||
VDAG_00526 | Nitrogen permease reactivator protein. (775 aa) | ||||
VDAG_00498 | Tyrosyl-DNA phosphodiesterase. (527 aa) | ||||
VDAG_00484 | Serine/threonine-protein phosphatase. (422 aa) | ||||
VDAG_01434 | Cell division cycle protein cdt2. (712 aa) | ||||
VDAG_09287 | FCY1p. (235 aa) | ||||
VDAG_09288 | Arabinogalactan endo-beta-1,4-galactanase. (349 aa) | ||||
SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (324 aa) | ||||
VDAG_09337 | Uncharacterized protein. (407 aa) | ||||
VDAG_09396 | ATP-dependent DNA helicase RecQ. (677 aa) | ||||
VDAG_09415 | Histone H2B; Belongs to the histone H2B family. (137 aa) | ||||
VDAG_09539 | WD repeat-containing protein. (565 aa) | ||||
VDAG_09770 | Nucleotide excision repair protein RAD23. (394 aa) | ||||
VDAG_09596 | Uncharacterized protein. (662 aa) | ||||
VDAG_09598 | AAA domain-containing protein. (1197 aa) | ||||
VDAG_09663 | Cell cycle control protein cwf8. (483 aa) | ||||
VDAG_09845 | Uncharacterized protein. (644 aa) | ||||
VDAG_09902 | MUS26 protein. (304 aa) | ||||
VDAG_09987 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (605 aa) | ||||
VDAG_10019 | RNA polymerase II transcription factor B subunit 1. (547 aa) | ||||
VDAG_10031 | DNA repair helicase RAD3. (772 aa) | ||||
VDAG_10082 | Uncharacterized protein. (412 aa) | ||||
VDAG_10083 | Mating-type switching protein swi10. (408 aa) | ||||
VDAG_10136 | Uncharacterized protein. (415 aa) | ||||
VDAG_10143 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (518 aa) | ||||
VDAG_10166 | Acriflavine sensitivity control protein acr-2. (297 aa) | ||||
VDAG_10264 | DNA mismatch repair protein hexB. (704 aa) | ||||
VDAG_10269 | Replication factor-A protein. (294 aa) | ||||
VDAG_10383 | Uncharacterized protein. (236 aa) | ||||
VDAG_10336 | Sister chromatid cohesion protein Eso1. (660 aa) | ||||
VDAG_10342 | Serine/threonine-protein kinase hal4; Belongs to the protein kinase superfamily. (489 aa) | ||||
VDAG_10288 | COP9 signalosome complex subunit 5. (373 aa) | ||||
VDAG_10309 | DNA repair and recombination protein RAD26. (1116 aa) | ||||
VDAG_10397 | RING finger protein. (583 aa) | ||||
VDAG_10422 | Pre-mRNA-splicing factor SYF1. (822 aa) | ||||
VDAG_10430 | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa) | ||||
VDAG_10455 | Cyclin mcs2. (359 aa) | ||||
VDAG_10487 | CMP/dCMP deaminase. (169 aa) | ||||
VDAG_10492 | 40S ribosomal protein S27a. (153 aa) | ||||
VDAG_08641 | TPR domain-containing protein. (513 aa) | ||||
VDAG_08649 | Uncharacterized protein. (489 aa) | ||||
VDAG_08650 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (617 aa) | ||||
VDAG_08769 | DNA polymerase lambda. (815 aa) | ||||
VDAG_08796 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (354 aa) | ||||
VDAG_08805 | DNA mismatch repair protein mutL. (992 aa) | ||||
VDAG_08811 | RPOL4c domain-containing protein. (160 aa) | ||||
VDAG_09054 | AZUL domain-containing protein. (722 aa) | ||||
VDAG_09168 | SAP domain-containing protein. (268 aa) | ||||
VDAG_09169 | Uncharacterized protein. (289 aa) | ||||
VDAG_08935 | Uncharacterized protein; Belongs to the actin family. (757 aa) | ||||
VDAG_08937 | YL1_C domain-containing protein. (198 aa) | ||||
VDAG_08950 | Activating signal cointegrator 1 complex subunit 3. (1980 aa) | ||||
VDAG_09023 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (151 aa) | ||||
VDAG_09041 | DNA mismatch repair protein PMS1. (1035 aa) | ||||
VDAG_08924 | Peptidyl-prolyl cis-trans isomerase E. (153 aa) | ||||
VDAG_09246 | Uncharacterized protein. (109 aa) | ||||
VDAG_08518 | Topoisomerase 1-associated factor 1. (1098 aa) | ||||
VDAG_08469 | Replication factor C subunit 4. (361 aa) | ||||
VDAG_08442 | Ubiquitin C-terminal hydrolase. (823 aa) | ||||
VDAG_08427 | 3'-5' exonuclease domain-containing protein. (583 aa) | ||||
VDAG_08425 | DNA-directed RNA polymerase II. (151 aa) | ||||
VDAG_08326 | Telo_bind domain-containing protein. (696 aa) | ||||
VDAG_08125 | AAA domain-containing protein. (1002 aa) | ||||
VDAG_07968 | ISWI chromatin-remodeling complex ATPase ISW1. (865 aa) | ||||
VDAG_07906 | Serine/threonine-protein phosphatase. (312 aa) | ||||
VDAG_07801 | Metallothionein-I transcription activator. (81 aa) | ||||
VDAG_07602 | ERCC4 domain-containing protein. (777 aa) | ||||
VDAG_07599 | DNA_binding_1 domain-containing protein. (104 aa) | ||||
VDAG_07639 | Replication factor C subunit 3. (393 aa) | ||||
VDAG_07631 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (738 aa) | ||||
VDAG_07541 | BTB/POZ domain-containing protein. (512 aa) | ||||
VDAG_07523 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (479 aa) | ||||
VDAG_07504 | RNA polymerase II transcription factor B subunit 4. (398 aa) | ||||
VDAG_07485 | Uncharacterized protein. (193 aa) | ||||
VDAG_07468 | Nuclear transport factor 2. (125 aa) | ||||
VDAG_07435 | Centrin-3. (191 aa) | ||||
VDAG_07377 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (476 aa) | ||||
VDAG_07403 | CMP/dCMP deaminase. (219 aa) | ||||
VDAG_07098 | DNA repair protein RAD14. (391 aa) | ||||
VDAG_07068 | DNA-directed RNA polymerase II subunit RPB3. (342 aa) | ||||
VDAG_03261 | Meiosis-specific serine/threonine-protein kinase MEK1. (1221 aa) | ||||
VDAG_03253 | Uncharacterized protein. (185 aa) | ||||
VDAG_03195 | Crossover junction endonuclease MUS81. (567 aa) | ||||
VDAG_03186 | Uncharacterized protein. (577 aa) | ||||
VDAG_02645 | Pre-mRNA-splicing factor ISY1. (245 aa) | ||||
VDAG_02614 | FHA domain-containing protein. (269 aa) | ||||
VDAG_02479 | UBX domain-containing protein. (463 aa) | ||||
VDAG_02445 | DNA-(Apurinic or apyrimidinic site) lyase. (550 aa) | ||||
VDAG_02438 | DNA polymerase. (1499 aa) | ||||
VDAG_02357 | PHO85 cyclin-1. (346 aa) | ||||
VDAG_02925 | PHO85 cyclin-6. (503 aa) | ||||
VDAG_02867 | Calcium/calmodulin-dependent protein kinase. (495 aa) | ||||
VDAG_02779 | COP9 signalosome complex subunit 2. (491 aa) | ||||
VDAG_02701 | FHA domain-containing protein. (758 aa) | ||||
VDAG_01966 | UmuC domain-containing protein. (570 aa) | ||||
VDAG_03357 | Fe2OG dioxygenase domain-containing protein. (239 aa) | ||||
VDAG_03443 | Ran1-like protein kinase. (523 aa) | ||||
VDAG_03453 | NAD-dependent deacetylase sirtuin-7. (382 aa) | ||||
VDAG_03516 | Uncharacterized protein. (338 aa) | ||||
VDAG_03540 | Uncharacterized protein. (105 aa) | ||||
VDAG_03060 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (843 aa) | ||||
VDAG_03070 | Uncharacterized protein. (448 aa) | ||||
VDAG_03689 | PHO85 cyclin-7. (226 aa) | ||||
VDAG_03725 | COP9 signalosome complex subunit 1. (466 aa) | ||||
VDAG_03749 | Zinc finger protein. (122 aa) | ||||
VDAG_03750 | DNA repair helicase RAD25. (792 aa) | ||||
VDAG_03864 | Bifunctional polynucleotide phosphatase/kinase. (422 aa) | ||||
VDAG_03915 | UDP-galactopyranose mutase. (329 aa) | ||||
VDAG_03923 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (461 aa) | ||||
VDAG_03929 | RING finger and CHY zinc finger domain-containing protein. (715 aa) | ||||
VDAG_03983 | DNA ligase. (813 aa) | ||||
VDAG_04066 | Uncharacterized protein. (828 aa) | ||||
VDAG_04229 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1144 aa) | ||||
VDAG_04259 | DNA cross-link repair protein pso2/snm1. (922 aa) | ||||
VDAG_04265 | N-glycosylase/DNA lyase. (414 aa) | ||||
VDAG_04281 | Polymerase. (916 aa) | ||||
VDAG_04282 | BTB domain-containing protein. (477 aa) | ||||
VDAG_04295 | DNA mismatch repair protein mutS. (1018 aa) | ||||
VDAG_04304 | ATP-dependent helicase SGS1. (1518 aa) | ||||
VDAG_04315 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) | ||||
VDAG_04316 | Vezatin domain-containing protein. (622 aa) | ||||
VDAG_04347 | COP9 signalosome complex subunit 4. (425 aa) | ||||
VDAG_04392 | DNA-directed RNA polymerase II subunit RPB7. (171 aa) | ||||
VDAG_04505 | Ubiquitin carboxyl-terminal hydrolase; Belongs to the peptidase C19 family. (771 aa) | ||||
VDAG_04135 | Ovarian-specific serine/threonine-protein kinase Lok. (593 aa) | ||||
VDAG_04167 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1181 aa) | ||||
VDAG_04192 | Replication factor C subunit 2. (380 aa) | ||||
VDAG_04206 | zf-GRF domain-containing protein. (370 aa) | ||||
VDAG_04932 | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (283 aa) | ||||
VDAG_04936 | CMP/dCMP-type deaminase domain-containing protein. (408 aa) | ||||
VDAG_04573 | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (381 aa) | ||||
VDAG_04648 | Uncharacterized protein. (332 aa) | ||||
VDAG_04677 | Uncharacterized protein. (285 aa) | ||||
VDAG_04707 | Helicase SWR1. (1812 aa) | ||||
VDAG_05037 | Poly [ADP-ribose] polymerase. (728 aa) | ||||
VDAG_05146 | BRCT domain-containing protein. (491 aa) | ||||
VDAG_05368 | SEC63 domain-containing protein. (460 aa) | ||||
VDAG_05395 | Artemis protein. (657 aa) | ||||
VDAG_05478 | Zds1. (964 aa) | ||||
VDAG_05492 | PHO85 cyclin-1. (354 aa) | ||||
VDAG_05511 | CHY zinc finger domain-containing protein. (694 aa) | ||||
VDAG_05522 | Ubiquitin carboxyl-terminal hydrolase. (953 aa) | ||||
VDAG_05625 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1260 aa) | ||||
VDAG_05292 | Zn(2)-C6 fungal-type domain-containing protein. (506 aa) | ||||
VDAG_05306 | C2H2-type domain-containing protein. (359 aa) | ||||
VDAG_05308 | Uncharacterized protein. (826 aa) | ||||
VDAG_05342 | Acriflavine sensitivity control protein acr-2. (562 aa) | ||||
VDAG_05720 | DNA ligase. (1012 aa) | ||||
VDAG_05739 | Uncharacterized protein. (611 aa) | ||||
VDAG_05761 | Ubiquitin carboxyl-terminal hydrolase; Belongs to the peptidase C19 family. (1451 aa) | ||||
VDAG_05895 | Cullin-4A; Belongs to the cullin family. (794 aa) | ||||
VDAG_05896 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2917 aa) | ||||
VDAG_05949 | Serine/threonine-protein kinase hal4; Belongs to the protein kinase superfamily. (452 aa) | ||||
VDAG_06299 | Tyrosyl-DNA phosphodiesterase domain-containing protein. (609 aa) | ||||
VDAG_06301 | RING-box protein. (119 aa) | ||||
VDAG_06357 | DNA ligase. (893 aa) | ||||
VDAG_06363 | Asparaginyl-tRNA synthetase. (588 aa) | ||||
VDAG_06395 | Uncharacterized protein. (1216 aa) | ||||
VDAG_06451 | DNA-directed RNA polymerases I. (149 aa) | ||||
VDAG_06463 | Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (750 aa) |