(5 nodes) p38MAPK cascade, and Stress response network (Penicillium rubens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pc13g13500	MAP kinase kinase kinase. (1342 aa)
	Pc13g07760	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
	Pc16g13300	Pc16g13300 protein. (592 aa)
	Pc22g16340	Pc22g16340 protein. (773 aa)
	sho1	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (291 aa)

Your Current Organism:

Penicillium rubens

NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Pc13g07760	Pc13g13500	B6H467	B6H3M0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase kinase kinase.	0.437
Pc13g07760	Pc16g13300	B6H467	B6HAM1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Pc16g13300 protein.	0.981
Pc13g07760	Pc22g16340	B6H467	B6HR41	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Pc22g16340 protein.	0.614
Pc13g07760	sho1	B6H467	B6HR44	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.712
Pc13g13500	Pc13g07760	B6H3M0	B6H467	MAP kinase kinase kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.437
Pc13g13500	Pc16g13300	B6H3M0	B6HAM1	MAP kinase kinase kinase.	Pc16g13300 protein.	0.992
Pc13g13500	Pc22g16340	B6H3M0	B6HR41	MAP kinase kinase kinase.	Pc22g16340 protein.	0.993
Pc13g13500	sho1	B6H3M0	B6HR44	MAP kinase kinase kinase.	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.601
Pc16g13300	Pc13g07760	B6HAM1	B6H467	Pc16g13300 protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.981
Pc16g13300	Pc13g13500	B6HAM1	B6H3M0	Pc16g13300 protein.	MAP kinase kinase kinase.	0.992
Pc16g13300	Pc22g16340	B6HAM1	B6HR41	Pc16g13300 protein.	Pc22g16340 protein.	0.670
Pc16g13300	sho1	B6HAM1	B6HR44	Pc16g13300 protein.	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.995
Pc22g16340	Pc13g07760	B6HR41	B6H467	Pc22g16340 protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.614
Pc22g16340	Pc13g13500	B6HR41	B6H3M0	Pc22g16340 protein.	MAP kinase kinase kinase.	0.993
Pc22g16340	Pc16g13300	B6HR41	B6HAM1	Pc22g16340 protein.	Pc16g13300 protein.	0.670
Pc22g16340	sho1	B6HR41	B6HR44	Pc22g16340 protein.	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.789
sho1	Pc13g07760	B6HR44	B6H467	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.712
sho1	Pc13g13500	B6HR44	B6H3M0	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	MAP kinase kinase kinase.	0.601
sho1	Pc16g13300	B6HR44	B6HAM1	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	Pc16g13300 protein.	0.995
sho1	Pc22g16340	B6HR44	B6HR41	High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	Pc22g16340 protein.	0.789