(12 nodes) Ketone body metabolism, and Thiolase network (Penicillium rubens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pc13g10810	Pc13g10810 protein. (693 aa)
	Pc13g09810	Pc13g09810 protein. (363 aa)
	Pc14g00590	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (538 aa)
	Pc18g01450	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (458 aa)
	Pc19g00460	Pc19g00460 protein. (314 aa)
	Pc20g14670	Pc20g14670 protein. (359 aa)
	Pc21g09480	Pc21g09480 protein. (601 aa)
	Pc22g00420	Pc22g00420 protein; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	Pc22g00960	Pc22g00960 protein. (698 aa)
	Pc22g06820	Pc22g06820 protein; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)
	Pc22g03940	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	Pc22g10140	Pc22g10140 protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)

Your Current Organism:

Penicillium rubens

NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Pc13g09810	Pc13g10810	B6H4N2	B6H417	Pc13g09810 protein.	Pc13g10810 protein.	0.448
Pc13g09810	Pc14g00590	B6H4N2	B6H5M0	Pc13g09810 protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.504
Pc13g09810	Pc18g01450	B6H4N2	B6HCE6	Pc13g09810 protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.939
Pc13g09810	Pc19g00460	B6H4N2	B6HD35	Pc13g09810 protein.	Pc19g00460 protein.	0.402
Pc13g09810	Pc20g14670	B6H4N2	B6HHF0	Pc13g09810 protein.	Pc20g14670 protein.	0.976
Pc13g09810	Pc21g09480	B6H4N2	B6HNN3	Pc13g09810 protein.	Pc21g09480 protein.	0.976
Pc13g09810	Pc22g00420	B6H4N2	B6HPF6	Pc13g09810 protein.	Pc22g00420 protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.656
Pc13g09810	Pc22g00960	B6H4N2	B6HPQ3	Pc13g09810 protein.	Pc22g00960 protein.	0.448
Pc13g09810	Pc22g03940	B6H4N2	B6HS79	Pc13g09810 protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.504
Pc13g09810	Pc22g06820	B6H4N2	B6HQ68	Pc13g09810 protein.	Pc22g06820 protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.692
Pc13g09810	Pc22g10140	B6H4N2	B6HV94	Pc13g09810 protein.	Pc22g10140 protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.656
Pc13g10810	Pc13g09810	B6H417	B6H4N2	Pc13g10810 protein.	Pc13g09810 protein.	0.448
Pc13g10810	Pc14g00590	B6H417	B6H5M0	Pc13g10810 protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.914
Pc13g10810	Pc18g01450	B6H417	B6HCE6	Pc13g10810 protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.920
Pc13g10810	Pc19g00460	B6H417	B6HD35	Pc13g10810 protein.	Pc19g00460 protein.	0.942
Pc13g10810	Pc20g14670	B6H417	B6HHF0	Pc13g10810 protein.	Pc20g14670 protein.	0.932
Pc13g10810	Pc21g09480	B6H417	B6HNN3	Pc13g10810 protein.	Pc21g09480 protein.	0.932
Pc13g10810	Pc22g00420	B6H417	B6HPF6	Pc13g10810 protein.	Pc22g00420 protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.950
Pc13g10810	Pc22g00960	B6H417	B6HPQ3	Pc13g10810 protein.	Pc22g00960 protein.	0.907
Pc13g10810	Pc22g03940	B6H417	B6HS79	Pc13g10810 protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.914