(6 nodes) MCM domain network (Penicillium rubens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pc13g15480	DNA helicase; Belongs to the MCM family. (896 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (812 aa)
	Pc21g15650	DNA helicase; Belongs to the MCM family. (719 aa)
	Pc21g10710	DNA helicase; Belongs to the MCM family. (953 aa)
	Pc16g10450	DNA helicase; Belongs to the MCM family. (999 aa)
	Pc16g08300	DNA helicase; Belongs to the MCM family. (879 aa)

Your Current Organism:

Penicillium rubens

NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	Pc13g15480	B6HQS3	B6H2T4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Pc16g08300	B6HQS3	B6H830	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Pc16g10450	B6HQS3	B6H856	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Pc21g10710	B6HQS3	B6HJD4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	Pc21g15650	B6HQS3	B6HJW3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
Pc13g15480	MCM7	B6H2T4	B6HQS3	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
Pc13g15480	Pc16g08300	B6H2T4	B6H830	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc13g15480	Pc16g10450	B6H2T4	B6H856	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc13g15480	Pc21g10710	B6H2T4	B6HJD4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc13g15480	Pc21g15650	B6H2T4	B6HJW3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g08300	MCM7	B6H830	B6HQS3	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
Pc16g08300	Pc13g15480	B6H830	B6H2T4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g08300	Pc16g10450	B6H830	B6H856	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g08300	Pc21g10710	B6H830	B6HJD4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g08300	Pc21g15650	B6H830	B6HJW3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g10450	MCM7	B6H856	B6HQS3	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
Pc16g10450	Pc13g15480	B6H856	B6H2T4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g10450	Pc16g08300	B6H856	B6H830	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g10450	Pc21g10710	B6H856	B6HJD4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
Pc16g10450	Pc21g15650	B6H856	B6HJW3	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999