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hypE hypE hypD hypD hypC hypC hypB hypB hypF hypF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hypEKEGG: rru:Rru_A0305 3.1e-82 hydrogenase expression/formation protein HypE K04655. (341 aa)
hypDHydrogenase expression/formation protein HypD; Psort location: Cytoplasmic, score: 8.96; Belongs to the HypD family. (370 aa)
hypCHydrogenase assembly chaperone HypC/HupF; Psort location: Cytoplasmic, score: 8.96. (98 aa)
hypBHydrogenase accessory protein HypB; KEGG: reh:H16_A1087 8.5e-16 ureG; UreA amidohydrolase (urease) regulatory and maturation protein UreG; Psort location: Cytoplasmic, score: 9.97. (291 aa)
hypFCarbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (759 aa)
Your Current Organism:
Providencia rustigianii
NCBI taxonomy Id: 500637
Other names: P. rustigianii DSM 4541, Providencia rustigianii DSM 4541, Providencia rustigianii str. DSM 4541, Providencia rustigianii strain DSM 4541
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