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| | EFB71856.1 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. (111 aa) |
| | EFB74033.1 | Hypothetical protein; KEGG: ecc:c2832 0.0094 yfbR; hypothetical protein YfbR K08722. (238 aa) |
| | rumB | 23S rRNA (uracil-5-)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (331 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (438 aa) |
| | HtpX_1 | Peptidase, M48 family; KEGG: cbu:CBU_0546 2.7e-58 htpX; heat shock protein HtpX K03799; Psort location: CytoplasmicMembrane, score: 9.46. (318 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (298 aa) |
| | folE | GTP cyclohydrolase I; KEGG: ypm:YP_1395 1.0e-97 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. (219 aa) |
| | Dps | Ferritin-like protein; KEGG: eci:UTI89_C0816 2.4e-59 dps; stationary phase nucleoid protein Dps K04047; Psort location: Cytoplasmic, score: 8.96; Belongs to the Dps family. (167 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (345 aa) |
| | ModE_1 | TOBE domain protein. (276 aa) |
| | ybeY | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (155 aa) |
| | msrB | methionine-R-sulfoxide reductase; KEGG: plu:plu2557 1.6e-53 msrB; peptide methionine sulfoxide reductase MsrB K07305; Psort location: Cytoplasmic, score: 8.96. (137 aa) |
| | tdk | Thymidine kinase; KEGG: plu:plu2497 5.2e-80 tdk; thymidine kinase K00857. (223 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. (202 aa) |
| | lapB | Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (390 aa) |
| | add | Adenosine deaminase; KEGG: aha:AHA_0273 5.3e-126 add-1; adenosine deaminase K01488; Psort location: Cytoplasmic, score: 8.96; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (333 aa) |
| | manA | KEGG: plu:plu2360 2.4e-137 manA; mannose-6-phosphate isomerase (phosphomannose isomerase) (phosphohexomutase) (PMI) K01809. (416 aa) |
| | CueR_1 | Transcriptional regulator, MerR family; KEGG: syn:sll0794 8.3e-09 corR, merR, cobH, cbiC; cobalt-dependent transcriptional regulator (MerR (mercuric resistance operon regulatory protein)-like domain in N-terminal half), precorrin isomerase, Precorrin-8X methylmutase (in C-terminal half) K01833; Psort location: Cytoplasmic, score: 8.96. (140 aa) |
| | EFB73624.1 | SWIM zinc finger domain protein; Psort location: Cytoplasmic, score: 8.96. (684 aa) |
| | XecA1 | Methionine synthase, vitamin-B12 independent; KEGG: eca:ECA3126 1.3e-170 metE; 5-methyltetrahydropteroyltriglutamate- homocystein e methyltransferase K00549; Psort location: Cytoplasmic, score: 8.96. (343 aa) |
| | EFB73701.1 | Hypothetical protein. (886 aa) |
| | EFB73702.1 | Phage/conjugal plasmid C-4 type zinc finger protein, TraR family. (73 aa) |
| | cutC | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (253 aa) |
| | NdhM | Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain protein; KEGG: bur:Bcep18194_B1541 0. aldehyde oxidase K00087. (931 aa) |
| | AdhB | Cytochrome C; KEGG: bpm:BURPS1710b_0915 2.4e-66 cytochrome c K00120. (411 aa) |
| | sufA | FeS assembly scaffold SufA; Psort location: Cytoplasmic, score: 8.96; Belongs to the HesB/IscA family. (153 aa) |
| | pepT | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (410 aa) |
| | CutA | Divalent cation tolerance protein, CutA1 family; Psort location: Cytoplasmic, score: 8.96. (130 aa) |
| | flhC | Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (196 aa) |
| | pyrC | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (349 aa) |
| | ModE_2 | TOBE domain protein; KEGG: mma:MM1578 0.0096 molybdate ABC transporter, ATP-binding protein K02017. (142 aa) |
| | Sxy | TfoX C-terminal domain protein. (200 aa) |
| | YcbX | MOSC domain protein; KEGG: spt:SPA1863 1.4e-05 hcr; NADH oxidoreductase Hcr. (360 aa) |
| | pepN | Membrane alanyl aminopeptidase; KEGG: plu:plu1755 0. pepN; aminopeptidase N K01256; Psort location: Cytoplasmic, score: 9.12. (872 aa) |
| | nudC | Hydrolase, NUDIX family; KEGG: plu:plu0488 1.5e-105 nudC; NADH pyrophosphatase K03659; Psort location: Cytoplasmic, score: 8.96; Belongs to the Nudix hydrolase family. NudC subfamily. (262 aa) |
| | galT | KEGG: vvy:VV2638 3.2e-151 galactose-1-phosphate uridylyltransferase K00964. (352 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (662 aa) |
| | thiH | Thiazole biosynthesis protein ThiH; KEGG: tte:TTE1073 1.1e-10 bioB; Biotin synthase and related enzymes K01012. (373 aa) |
| | pepT-2 | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (420 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa) |
| | EFB72878.1 | Metallo-beta-lactamase domain protein; KEGG: afu:AF0939 2.7e-10 ribonuclease Z K00784. (251 aa) |
| | feoA | Ferrous iron transport protein A. (76 aa) |
| | feoC | Hypothetical protein; May function as a transcriptional regulator that controls feoABC expression. (77 aa) |
| | yhgI | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (192 aa) |
| | EFB73062.1 | Amidase, hydantoinase/carbamoylase family; KEGG: lmo:lmo0537 1.3e-69 N-carbamoyl-L-amino acid amidohydrolase; Psort location: Cytoplasmic, score: 8.96. (413 aa) |
| | dmsA | KEGG: ecj:JW5118 0. dmsA; dimethyl sulfoxide reductase, anaerobic, subunit A K07306; Psort location: Periplasmic, score: 9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa) |
| | FdhF_1 | Oxidoreductase alpha (molybdopterin) subunit; KEGG: eci:UTI89_C1715 7.2e-296 ydeP; hypothetical protein YdeP K00122; Psort location: Periplasmic, score: 9.44; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (764 aa) |
| | YiiM | MOSC domain protein; Psort location: Cytoplasmic, score: 8.96. (226 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (196 aa) |
| | map | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (265 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (331 aa) |
| | FtsP | Multicopper oxidase; KEGG: eci:UTI89_C3443 9.4e-152 sufI; FtsI suppressor K04753; Psort location: Periplasmic, score: 9.44. (447 aa) |
| | YgiD | Aromatic ring-opening dioxygenase, catalytic subunit LigB; KEGG: azo:azo2868 1.7e-40 ygiD; protocatechuate 4,5-dioxygenase K04099. (256 aa) |
| | ribB | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (217 aa) |
| | tsaD | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (339 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (581 aa) |
| | hypC | Hydrogenase assembly chaperone HypC/HupF; Psort location: Cytoplasmic, score: 8.96. (98 aa) |
| | hypB | Hydrogenase accessory protein HypB; KEGG: reh:H16_A1087 8.5e-16 ureG; UreA amidohydrolase (urease) regulatory and maturation protein UreG; Psort location: Cytoplasmic, score: 9.97. (291 aa) |
| | hypA | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa) |
| | hybE | Hydrogenase-2 assembly chaperone HybE; Psort location: Cytoplasmic, score: 8.96. (166 aa) |
| | hybC | Hydrogenase-2 large chain; KEGG: ecj:JW2962 9.1e-257 hybC; hydrogenase 2, large subunit K06281; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa) |
| | hypF | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (759 aa) |
| | EFB72226.1 | Fatty acid hydroxylase superfamily; KEGG: mtu:Rv1814 3.8e-29 erg3; C-5 sterol desaturase K00258; Psort location: CytoplasmicMembrane, score: 10.00; overlaps another CDS with the same product name. (375 aa) |
| | araD | KEGG: ypm:YP_0360 5.7e-97 araD1; L-ribulose-5-phosphate 4-epimerase K01786; Psort location: Cytoplasmic, score: 8.96. (232 aa) |
| | hypA-2 | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa) |
| | hypC-2 | Hydrogenase assembly chaperone HypC/HupF; Psort location: Cytoplasmic, score: 8.96. (90 aa) |
| | cah | Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (227 aa) |
| | NdhI | 4Fe-4S binding domain protein; KEGG: eco:b2488 1.0e-51 hyfH; hydrogenase 4 Fe-S subunit. (183 aa) |
| | HyfG | Respiratory-chain NADH dehydrogenase, 30 Kd subunit; KEGG: eca:ECA1241 2.3e-267 hyfG; hydrogenase-4 component G; Psort location: Periplasmic, score: 9.44. (577 aa) |
| | pepA | Cytosol aminopeptidase family, catalytic domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa) |
| | hflB | Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (655 aa) |
| | nsrR | HTH-type transcriptional repressor NsrR; KEGG: ama:AM656 0.00045 aminotransferase, class V K04487; Psort location: Cytoplasmic, score: 8.96. (142 aa) |
| | EFB72471.1 | Oxidoreductase, 2OG-Fe(II) oxygenase family protein; KEGG: dre:406602 7.9e-13 egln3; egl nine homolog 3 (C. elegans). (194 aa) |
| | cyaY | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (105 aa) |
| | wecA | Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (361 aa) |
| | hutI | Imidazolonepropionase; KEGG: plu:plu3197 1.9e-114 hutI; imidazolonepropionase (imidazolone-5-propionate hydrolase) K01468. (325 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (473 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (373 aa) |
| | PepB | Cytosol aminopeptidase family, catalytic domain protein; Probably plays an important role in intracellular peptide degradation. (438 aa) |
| | iscX | FeS assembly protein IscX; Psort location: Cytoplasmic, score: 8.96. (66 aa) |
| | iscA | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. (135 aa) |
| | iscU | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa) |
| | iscR | Iron-sulfur cluster assembly transcription factor IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (165 aa) |
| | GuaD | Cytidine and deoxycytidylate deaminase zinc-binding region; KEGG: reh:H16_B0797 6.3e-27 cytosine deaminase-related enzyme K01493. (154 aa) |
| | tadA | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (176 aa) |
| | hutG | Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (305 aa) |
| | EFB72050.1 | Hypothetical protein. (511 aa) |
| | EFB72066.1 | Terminase small subunit; Psort location: Cytoplasmic, score: 8.96. (130 aa) |
| | EFB72093.1 | GroES-like protein; KEGG: xac:XAC2896 3.6e-111 alcohol dehydrogenase K00001. (337 aa) |
| | FrmA_2 | KEGG: eci:UTI89_C0376 4.4e-193 adhC; alcohol dehydrogenase class III; formaldehyde dehydrogenase, glutathione-dependent K00001:K00121; Psort location: Cytoplasmic, score: 9.97; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa) |
| | ZinT | YodA. (214 aa) |
| | yacG | Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (65 aa) |
| | speB | Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (306 aa) |
| | sprT | Metallopeptidase, SprT family; Belongs to the SprT family. (175 aa) |
| | napA | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa) |
| | nrfA | Formate-dependent cytochrome c nitrite reductase, c552 subunit; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (477 aa) |
| | cysS | cysteine--tRNA ligase; KEGG: ypn:YPN_1017 2.1e-216 cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. (462 aa) |
| | lpxH | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa) |
| | rumA | 23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (427 aa) |
| | erpA | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (114 aa) |
| | dksA | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. (184 aa) |
| | cah-2 | Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (217 aa) |
| | CueO | Tat pathway signal sequence domain protein; KEGG: eci:UTI89_C0136 2.9e-180 cueO; blue copper oxidase CueO precursor; Psort location: Periplasmic, score: 9.44. (548 aa) |
| | EFB71514.1 | Phage/conjugal plasmid C-4 type zinc finger protein, TraR family; Psort location: Cytoplasmic, score: 8.96. (73 aa) |
| | htpX | Peptidase, M48 family; KEGG: eca:ECA2427 4.8e-132 htpX; heat shock protein K03799; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the peptidase M48B family. (294 aa) |
| | YebZ | Copper resistance protein D; Psort location: CytoplasmicMembrane, score: 10.00. (298 aa) |
| | YobA | Copper resistance protein CopC; Psort location: Periplasmic, score: 9.44. (128 aa) |
| | FtnA | Ferritin-like protein; Iron-storage protein. (167 aa) |
| | EFB71541.1 | Hydrolase, NUDIX family; KEGG: vfi:VF1178 9.3e-26 CoA pyrophosphatase K01529; Belongs to the Nudix hydrolase family. PCD1 subfamily. (186 aa) |
| | YcdX | Putative hydrolase; KEGG: eci:UTI89_C1155 1.0e-83 ycdX; hypothetical protein K04477; Psort location: Cytoplasmic, score: 8.96; Belongs to the PHP family. (248 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (376 aa) |
| | bepA | Tetratricopeptide repeat protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (487 aa) |
| | pepT-3 | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (414 aa) |
| | cobB | KEGG: yps:YPTB2438 6.2e-100 cobB; putative Sir2 family protein K01463; Belongs to the sirtuin family. Class III subfamily. (240 aa) |
| | rne | S1 RNA binding domain protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1069 aa) |
| | nfo | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (281 aa) |
| | EFB71295.1 | Hypothetical protein. (170 aa) |
| | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (557 aa) |
| | nuoI | NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa) |
| | nuoB | NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (323 aa) |
| | EFB71396.1 | Hypothetical protein; KEGG: plu:plu3197 4.3e-28 hutI; imidazolonepropionase (imidazolone-5-propionate hydrolase) K01468. (85 aa) |
| | luxS | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (875 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (192 aa) |
| | YggX | Putative Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. (89 aa) |
| | hpaD | KEGG: plu:plu0987 1.1e-141 hpcB; 3,4-dihydroxyphenylacetate 2,3-dioxygenase K00455; Psort location: Cytoplasmic, score: 8.96. (293 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa) |
| | queC | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (231 aa) |
| | clpX | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (425 aa) |
| | cyoA | Ubiquinol oxidase, subunit II; KEGG: plu:plu3875 5.4e-124 cyoA; ubiquinol oxidase polypeptide II precursor (cytochrome O subunit 2) (oxidase BO(3) subunit 2) (cytochrome O ubiquinol oxidase subunit 2) (ubiquinol oxidase chain B) K02297; Psort location: CytoplasmicMembrane, score: 10.00. (347 aa) |
| | ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa) |
| | nrdR | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (107 aa) |
| | kduI | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (295 aa) |
| | GatY | Class II aldolase, tagatose bisphosphate family; KEGG: ppr:PBPRB0157 3.4e-115 putative aldolase K08302; Psort location: Cytoplasmic, score: 8.96. (276 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (936 aa) |
| | MtaD | Amidohydrolase family protein; KEGG: mma:MM2279 1.9e-73 N-ethylammeline chlorohydrolase K01564; Psort location: Cytoplasmic, score: 8.96. (430 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (380 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (407 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (759 aa) |
| | QorA | GroES-like protein; KEGG: eca:ECA3663 3.6e-127 qor, hcz; quinone oxidoreductase K00344. (327 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities. (306 aa) |
| | metH | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa) |
| | EFB70919.1 | Hypothetical protein. (264 aa) |
| | UlaG | Hypothetical protein; KEGG: spi:MGAS10750_Spy0162 1.4e-107 metal-dependent hydrolase. (355 aa) |
| | fdhE | Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (339 aa) |
| | mutM | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (269 aa) |
| | tdh | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa) |
| | EFB70753.1 | Phage/conjugal plasmid C-4 type zinc finger protein, TraR family; Psort location: Cytoplasmic, score: 8.96. (73 aa) |
| | argE | KEGG: yps:YPTB0109 1.6e-172 argE; acetylornithine deacetylase K01438. (384 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa) |
| | zntR | KEGG: eci:UTI89_C3737 2.9e-47 yhdM; Zn(II)-responsive regulator of ZntA; Psort location: Cytoplasmic, score: 8.96. (140 aa) |
| | bfr | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (157 aa) |
| | EFB70458.1 | DnaJ domain protein; Psort location: Cytoplasmic, score: 8.96. (171 aa) |
