STRINGSTRING
EFC56148.1 EFC56148.1 EFC53537.1 EFC53537.1 purU purU EFC55296.1 EFC55296.1 ilvN-2 ilvN-2 spoT spoT PheA PheA EFC54483.1 EFC54483.1 EFC54596.1 EFC54596.1 EFC56837.1 EFC56837.1 EFC57765.1 EFC57765.1 ilvN ilvN glnD glnD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFC56148.1ACT domain protein; KEGG: eci:UTI89_C2806 4.4e-61 gcvR; glycine cleavage system transcriptional repressor K03567; Psort location: Cytoplasmic, score: 9.97. (147 aa)
EFC53537.1KEGG: ent:Ent638_4014 1.0e-38 ilvM; acetolactate synthase 2 regulatory subunit K11258. (87 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (280 aa)
EFC55296.1Aspartate kinase, monofunctional class; KEGG: ent:Ent638_0229 3.7e-215 aspartate kinase III K00928; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family. (449 aa)
ilvN-2KEGG: ent:Ent638_0026 2.1e-45 acetolactate synthase 1 regulatory subunit K01653; Psort location: Cytoplasmic, score: 8.96. (95 aa)
spoTGuanosine 3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (705 aa)
PheAChorismate mutase; KEGG: ent:Ent638_3077 1.4e-192 pheA; bifunctional chorismate mutase/prephenate dehydratase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97. (386 aa)
EFC54483.1RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (743 aa)
EFC54596.1KEGG: ent:Ent638_3332 4.7e-206 D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa)
EFC56837.1Sigma-54 interaction domain protein; KEGG: eci:UTI89_C2502 8.9e-54 atoC; acetoacetate metabolism regulatory protein AtoC K07714; Psort location: Cytoplasmic, score: 8.96. (513 aa)
EFC57765.1Homoserine dehydrogenase; KEGG: ent:Ent638_0564 0. thrA; bifunctional aspartokinase I/homeserine dehydrogenase I; K00003 homoserine dehydrogenase K00928; Psort location: Cytoplasmic, score: 8.96; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa)
ilvNAcetolactate synthase, small subunit; KEGG: ent:Ent638_0625 1.0e-77 ilvH; acetolactate synthase 3 regulatory subunit K01653; Psort location: Cytoplasmic, score: 8.96. (163 aa)
glnDprotein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (902 aa)
Your Current Organism:
Enterobacter cancerogenus
NCBI taxonomy Id: 500639
Other names: E. cancerogenus ATCC 35316, Enterobacter cancerogenus ATCC 35316, Enterobacter cancerogenus str. ATCC 35316, Enterobacter cancerogenus strain ATCC 35316
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