(16 nodes) Sphingolipid metabolism network (Paracoccidioides brasiliensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PADG_02979	CCHC-type domain-containing protein. (327 aa)
	PADG_01514	Uncharacterized protein. (180 aa)
	PADG_01622	Uncharacterized protein. (573 aa)
	PADG_01990	Aminotran_1_2 domain-containing protein. (684 aa)
	PADG_02876	DAGKc domain-containing protein. (515 aa)
	PADG_02892	Uncharacterized protein. (385 aa)
	PADG_03378	acidPPc domain-containing protein. (547 aa)
	PADG_03707	Endo/exonuclease/phosphatase domain-containing protein. (521 aa)
	PADG_04921	Aminotran_1_2 domain-containing protein. (507 aa)
	PADG_04552	TLC domain-containing protein. (408 aa)
	PADG_05702	TLC domain-containing protein. (465 aa)
	PADG_05719	NAAA-beta domain-containing protein. (475 aa)
	PADG_06550	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (423 aa)
	PADG_07478	Uncharacterized protein. (513 aa)
	PADG_08266	Sphingolipid delta(4)-desaturase; Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides. (411 aa)
	PADG_08198	Neutral ceramidase. (763 aa)

Your Current Organism:

Paracoccidioides brasiliensis

NCBI taxonomy Id: 502780
Other names: P. brasiliensis Pb18, Paracoccidioides brasiliensis Pb18

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PADG_01514	PADG_01990	C1G3J8	C1G4X4	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.914
PADG_01514	PADG_04921	C1G3J8	C1GBC0	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.934
PADG_01622	PADG_01990	C1G3V6	C1G4X4	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.573
PADG_01622	PADG_02876	C1G3V6	C1G6S1	Uncharacterized protein.	DAGKc domain-containing protein.	0.969
PADG_01622	PADG_03378	C1G3V6	C1G873	Uncharacterized protein.	acidPPc domain-containing protein.	0.974
PADG_01622	PADG_04921	C1G3V6	C1GBC0	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.526
PADG_01990	PADG_01514	C1G4X4	C1G3J8	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.914
PADG_01990	PADG_01622	C1G4X4	C1G3V6	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.573
PADG_01990	PADG_02876	C1G4X4	C1G6S1	Aminotran_1_2 domain-containing protein.	DAGKc domain-containing protein.	0.634
PADG_01990	PADG_02892	C1G4X4	C1G6T7	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.986
PADG_01990	PADG_02979	C1G4X4	A0A0A0HWA6	Aminotran_1_2 domain-containing protein.	CCHC-type domain-containing protein.	0.611
PADG_01990	PADG_03378	C1G4X4	C1G873	Aminotran_1_2 domain-containing protein.	acidPPc domain-containing protein.	0.475
PADG_01990	PADG_03707	C1G4X4	C1G8X1	Aminotran_1_2 domain-containing protein.	Endo/exonuclease/phosphatase domain-containing protein.	0.621
PADG_01990	PADG_04921	C1G4X4	C1GBC0	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.999
PADG_01990	PADG_06550	C1G4X4	C1GH14	Aminotran_1_2 domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.499
PADG_01990	PADG_07478	C1G4X4	C1GJP2	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.609
PADG_01990	PADG_08198	C1G4X4	C1GMB2	Aminotran_1_2 domain-containing protein.	Neutral ceramidase.	0.604
PADG_01990	PADG_08266	C1G4X4	C1GLM5	Aminotran_1_2 domain-containing protein.	Sphingolipid delta(4)-desaturase; Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.	0.746
PADG_02876	PADG_01622	C1G6S1	C1G3V6	DAGKc domain-containing protein.	Uncharacterized protein.	0.969
PADG_02876	PADG_01990	C1G6S1	C1G4X4	DAGKc domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.634