STRINGSTRING
PADG_12018 PADG_12018 PADG_05907 PADG_05907 PADG_05676 PADG_05676 PADG_11211 PADG_11211 PADG_01112 PADG_01112 PADG_05400 PADG_05400 PADG_05078 PADG_05078 PADG_00718 PADG_00718 PADG_01588 PADG_01588 PADG_01848 PADG_01848 PADG_04285 PADG_04285
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PADG_12018HUN domain-containing protein. (290 aa)
PADG_05907Histone H2B; Belongs to the histone H2B family. (141 aa)
PADG_05676Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2935 aa)
PADG_11211Telo_bind domain-containing protein. (336 aa)
PADG_01112Uncharacterized protein. (316 aa)
PADG_05400Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (517 aa)
PADG_05078Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (791 aa)
PADG_00718Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (299 aa)
PADG_01588AAA_23 domain-containing protein. (1335 aa)
PADG_01848Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1110 aa)
PADG_04285Uncharacterized protein. (1679 aa)
Your Current Organism:
Paracoccidioides brasiliensis
NCBI taxonomy Id: 502780
Other names: P. brasiliensis Pb18, Paracoccidioides brasiliensis Pb18
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.