STRINGSTRING
N301_04556 N301_04556 N301_15010 N301_15010 N301_03028 N301_03028 N301_06333 N301_06333 N301_09246 N301_09246 N301_14067 N301_14067 N301_13559 N301_13559 N301_11940 N301_11940 N301_00246 N301_00246 N301_12809 N301_12809 N301_10902 N301_10902 N301_04864 N301_04864 N301_06759 N301_06759 N301_07702 N301_07702 N301_16152 N301_16152 N301_08445 N301_08445 N301_13824 N301_13824 N301_00100 N301_00100 N301_10170 N301_10170 N301_15388 N301_15388 N301_15371 N301_15371 N301_08609 N301_08609 N301_07990 N301_07990 N301_01089 N301_01089 N301_08602 N301_08602 N301_14941 N301_14941 N301_08605 N301_08605 N301_03335 N301_03335 N301_03398 N301_03398 N301_14942 N301_14942 N301_12366 N301_12366 N301_05205 N301_05205 N301_07135 N301_07135 N301_01983 N301_01983 N301_10817 N301_10817 N301_01348 N301_01348 N301_05971 N301_05971 N301_05978 N301_05978 N301_06708 N301_06708 N301_08301 N301_08301 N301_03695 N301_03695 N301_05481 N301_05481 N301_10272 N301_10272 N301_00451 N301_00451 N301_00449 N301_00449 N301_11018 N301_11018 N301_06111 N301_06111 FEN1 FEN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
N301_04556Cell cycle checkpoint control protein RAD9A. (160 aa)
N301_15010Tumor suppressor p53-binding protein 1. (1827 aa)
N301_03028RAD51-associated protein 1. (89 aa)
N301_06333ATP-dependent DNA helicase Q5. (1007 aa)
N301_09246DNA repair protein RAD50. (1312 aa)
N301_14067Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2667 aa)
N301_13559DNA replication ATP-dependent helicase/nuclease DNA2. (1004 aa)
N301_11940DNA topoisomerase 2-binding protein 1. (504 aa)
N301_00246Checkpoint protein HUS1. (266 aa)
N301_12809RAD9, HUS1, RAD1-interacting nuclear orphan protein 1. (243 aa)
N301_10902Cell cycle checkpoint protein RAD1. (219 aa)
N301_04864Ankyrin repeat domain-containing protein 12. (1916 aa)
N301_06759RNA-directed DNA polymerase from mobile element jockey. (110 aa)
N301_07702Replication protein A 14 kDa subunit. (82 aa)
N301_16152DNA repair protein RAD52. (420 aa)
N301_08445Cell cycle checkpoint control protein RAD9B. (401 aa)
N301_13824Uncharacterized protein. (1287 aa)
N301_00100Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family. (700 aa)
N301_10170Meiotic recombination protein DMC1/LIM15; Belongs to the RecA family. (346 aa)
N301_15388DNA repair protein RAD51 3. (327 aa)
N301_15371Fanconi anemia group J protein. (1261 aa)
N301_08609Exonuclease 3'-5' domain-containing protein 2. (621 aa)
N301_07990F-box only protein 18. (1021 aa)
N301_01089Microcephalin. (493 aa)
N301_08602DNA repair protein RAD51 2. (253 aa)
N301_14941Ankyrin repeat domain-containing protein 32. (422 aa)
N301_08605Uncharacterized protein. (41 aa)
N301_03335Uncharacterized protein. (710 aa)
N301_03398ATP-dependent DNA helicase; Belongs to the helicase family. (362 aa)
N301_14942Ankyrin repeat domain-containing protein 32. (215 aa)
N301_12366Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
N301_05205Werner syndrome ATP-dependent helicase. (1364 aa)
N301_07135Tudor domain-containing protein 3. (726 aa)
N301_01983BRCA1-associated RING domain protein 1. (722 aa)
N301_10817DNA endonuclease RBBP8. (908 aa)
N301_01348RecQ-mediated genome instability protein 2. (49 aa)
N301_05971DNA repair protein XRCC2. (266 aa)
N301_05978PAX-interacting protein 1. (1036 aa)
N301_06708DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (998 aa)
N301_08301DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (839 aa)
N301_03695Serine/threonine-protein kinase Chk2. (464 aa)
N301_05481DNA repair protein XRCC3. (347 aa)
N301_10272RecQ-mediated genome instability protein 1. (627 aa)
N301_00451Uncharacterized protein. (48 aa)
N301_00449DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
N301_11018Replication protein A 32 kDa subunit. (232 aa)
N301_06111Meiotic recombination protein SPO11. (353 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
Your Current Organism:
Charadrius vociferus
NCBI taxonomy Id: 50402
Other names: Aegialitis vocifera, C. vociferus, Charadrius vociferous, Oxyechus vociferus, killdeer
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