node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
N301_01014 | N301_13580 | A0A0A0A535 | A0A0A0ABU6 | Calcineurin B homologous protein 1. | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.973 |
N301_02012 | N301_10285 | A0A0A0AWP7 | A0A0A0A9W6 | Stromal interaction molecule 1. | Stromal interaction molecule 2. | 0.969 |
N301_03936 | N301_10764 | A0A0A0AXN5 | A0A0A0AGQ2 | Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. | Endothelin-1. | 0.994 |
N301_04019 | N301_07159 | A0A0A0AY53 | A0A0A0ATR5 | ATP-binding cassette sub-family C member 8. | Na(+)/H(+) exchange regulatory cofactor NHE-RF3. | 0.430 |
N301_04019 | N301_16022 | A0A0A0AY53 | A0A0A0AVV7 | ATP-binding cassette sub-family C member 8. | Huntingtin. | 0.459 |
N301_07159 | N301_04019 | A0A0A0ATR5 | A0A0A0AY53 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3. | ATP-binding cassette sub-family C member 8. | 0.430 |
N301_07159 | N301_10467 | A0A0A0ATR5 | A0A0A0AGP5 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | 0.725 |
N301_08044 | N301_14825 | A0A0A0ANE8 | A0A099ZVJ3 | Serine/threonine-protein kinase WNK3. | Cyclin N-terminal domain-containing protein 1. | 0.520 |
N301_08068 | N301_10218 | A0A0A0A2W7 | A0A0A0A9W8 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.882 |
N301_08068 | N301_10585 | A0A0A0A2W7 | A0A0A0AF09 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent L-type calcium channel subunit beta-4. | 0.864 |
N301_10218 | N301_08068 | A0A0A0A9W8 | A0A0A0A2W7 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.882 |
N301_10218 | N301_10585 | A0A0A0A9W8 | A0A0A0AF09 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent L-type calcium channel subunit beta-4. | 0.934 |
N301_10285 | N301_02012 | A0A0A0A9W6 | A0A0A0AWP7 | Stromal interaction molecule 2. | Stromal interaction molecule 1. | 0.969 |
N301_10467 | N301_07159 | A0A0A0AGP5 | A0A0A0ATR5 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | Na(+)/H(+) exchange regulatory cofactor NHE-RF3. | 0.725 |
N301_10467 | N301_16022 | A0A0A0AGP5 | A0A0A0AVV7 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | Huntingtin. | 0.450 |
N301_10585 | N301_08068 | A0A0A0AF09 | A0A0A0A2W7 | Voltage-dependent L-type calcium channel subunit beta-4. | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.864 |
N301_10585 | N301_10218 | A0A0A0AF09 | A0A0A0A9W8 | Voltage-dependent L-type calcium channel subunit beta-4. | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.934 |
N301_10764 | N301_03936 | A0A0A0AGQ2 | A0A0A0AXN5 | Endothelin-1. | Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. | 0.994 |
N301_13580 | N301_01014 | A0A0A0ABU6 | A0A0A0A535 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | Calcineurin B homologous protein 1. | 0.973 |
N301_13580 | N301_15182 | A0A0A0ABU6 | A0A0A0AKY2 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | Calcineurin B homologous protein 3. | 0.898 |