STRINGSTRING
N301_06320 N301_06320 N301_05323 N301_05323 N301_15010 N301_15010 N301_09246 N301_09246 N301_08681 N301_08681 N301_10055 N301_10055 N301_05919 N301_05919 N301_03164 N301_03164 N301_07013 N301_07013 N301_07934 N301_07934 N301_15288 N301_15288 N301_12368 N301_12368 N301_03398 N301_03398 N301_10436 N301_10436 N301_12366 N301_12366 N301_11068 N301_11068 N301_09588 N301_09588 N301_13109 N301_13109 N301_02757 N301_02757 N301_04481 N301_04481 N301_06014 N301_06014 N301_02330 N301_02330
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
N301_06320CST complex subunit TEN1. (119 aa)
N301_05323Protein SMG7. (1131 aa)
N301_15010Tumor suppressor p53-binding protein 1. (1827 aa)
N301_09246DNA repair protein RAD50. (1312 aa)
N301_08681Telomeric repeat-binding factor 2-interacting protein 1. (173 aa)
N301_10055Homeobox-containing protein 1. (391 aa)
N301_05919X-ray repair cross-complementing protein 5. (598 aa)
N301_03164CST complex subunit CTC1. (116 aa)
N301_07013CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (375 aa)
N301_07934Regulator of nonsense transcripts 2. (1268 aa)
N301_15288Zinc finger and BTB domain-containing protein 48. (378 aa)
N301_12368Telomerase-binding protein EST1A. (1377 aa)
N301_03398ATP-dependent DNA helicase; Belongs to the helicase family. (362 aa)
N301_10436Protection of telomeres protein 1. (786 aa)
N301_12366Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
N301_11068Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family. (3633 aa)
N301_09588X-ray repair cross-complementing protein 5. (697 aa)
N301_13109Telomere length regulation protein TEL2. (686 aa)
N301_02757Regulator of nonsense transcripts 1. (1054 aa)
N301_04481DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (160 aa)
N301_06014Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1251 aa)
N301_02330Adrenocortical dysplasia protein. (343 aa)
Your Current Organism:
Charadrius vociferus
NCBI taxonomy Id: 50402
Other names: Aegialitis vocifera, C. vociferus, Charadrius vociferous, Oxyechus vociferus, killdeer
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