STRINGSTRING
N301_03164 N301_03164 N301_10436 N301_10436 N301_12366 N301_12366 N301_09246 N301_09246 N301_07013 N301_07013
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
N301_03164CST complex subunit CTC1. (116 aa)
N301_10436Protection of telomeres protein 1. (786 aa)
N301_12366Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
N301_09246DNA repair protein RAD50. (1312 aa)
N301_07013CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (375 aa)
Your Current Organism:
Charadrius vociferus
NCBI taxonomy Id: 50402
Other names: Aegialitis vocifera, C. vociferus, Charadrius vociferous, Oxyechus vociferus, killdeer
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.