STRINGSTRING
Slin_0254 Slin_0254 Slin_0360 Slin_0360 pgi pgi Slin_0529 Slin_0529 gpmA gpmA Slin_0798 Slin_0798 Slin_1235 Slin_1235 fbp fbp Slin_1742 Slin_1742 Slin_1998 Slin_1998 Slin_2042 Slin_2042 Slin_2333 Slin_2333 Slin_2562 Slin_2562 Slin_2646 Slin_2646 Slin_2711 Slin_2711 acsA acsA Slin_2977 Slin_2977 Slin_2990 Slin_2990 Slin_3046 Slin_3046 Slin_3069 Slin_3069 pgk pgk Slin_3540 Slin_3540 Slin_3541 Slin_3541 Slin_3779 Slin_3779 Slin_4063 Slin_4063 Slin_4168 Slin_4168 Slin_4200 Slin_4200 pfkA pfkA gpmI gpmI eno eno Slin_5156 Slin_5156 Slin_5165 Slin_5165 pdhA pdhA tpiA tpiA Slin_5752 Slin_5752 Slin_6035 Slin_6035 Slin_6585 Slin_6585
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Slin_0254Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
Slin_0360PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: mxa:MXAN_7323 zinc-binding dehydrogenase family oxidoreductase. (347 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: dal:Dalk_1023 glucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
Slin_0529Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (586 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (204 aa)
Slin_0798PFAM: Aldehyde Dehydrogenase; KEGG: bur:Bcep18194_B2693 aldehyde dehydrogenase. (540 aa)
Slin_1235Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (387 aa)
fbpPFAM: Inositol phosphatase/fructose-16- bisphosphatase; KEGG: vsp:VS_2771 fructose-1,6-bisphosphatase. (333 aa)
Slin_1742PFAM: Aldehyde Dehydrogenase; KEGG: pol:Bpro_5303 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (476 aa)
Slin_1998KEGG: geo:Geob_2897 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
Slin_2042acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (636 aa)
Slin_2333PFAM: Aldehyde Dehydrogenase; KEGG: noc:Noc_2916 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (504 aa)
Slin_2562PFAM: ROK family protein; KEGG: ara:Arad_9637 transcriptional regulator protein. (314 aa)
Slin_2646PFAM: ROK family protein; KEGG: ank:AnaeK_0168 ROK family protein. (298 aa)
Slin_2711TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpd:RPD_2835 HAD family hydrolase. (217 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (631 aa)
Slin_2977Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (397 aa)
Slin_2990PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: scl:sce4837 putative phosphoglucomutase/phosphomannomutase. (585 aa)
Slin_3046PFAM: Aldose 1-epimerase; KEGG: vsp:VS_II1385 galactose mutarotase and related enzymes. (345 aa)
Slin_3069PFAM: Aldehyde Dehydrogenase; KEGG: dat:HRM2_38600 NAD-dependent aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (508 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: hypothetical protein; K00927 phosphoglycerate kinase. (395 aa)
Slin_3540PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: bam:Bamb_3870 alcohol dehydrogenase. (337 aa)
Slin_3541TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; hydroxyethylthiazole kinase; KEGG: gbm:Gbem_3234 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (332 aa)
Slin_3779PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: psa:PST_3017 oxidoreductase, zinc-binding. (348 aa)
Slin_4063KEGG: gbm:Gbem_1182 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (488 aa)
Slin_4168Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: esa:ESA_02983 hypothetical protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
Slin_4200PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: scl:sce0475 alcohol dehydrogenase. (385 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (525 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
Slin_5156PFAM: ROK family protein; KEGG: gme:Gmet_1639 glucokinase. (304 aa)
Slin_5165Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (352 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)
Slin_5752TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: ara:Arad_2251 dihydrolipoamide dehydrogenase. (466 aa)
Slin_6035TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: mch:Mchl_1930 dihydrolipoamide dehydrogenase. (466 aa)
Slin_6585PFAM: ROK family protein; KEGG: ftw:FTW_0827 ROK family protein. (278 aa)
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
Server load: low (12%) [HD]