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pyrB pyrB argH argH Slin_0407 Slin_0407 Slin_0568 Slin_0568 purA purA Slin_1914 Slin_1914 Slin_2233 Slin_2233 Slin_2319 Slin_2319 Slin_2320 Slin_2320 Slin_2431 Slin_2431 Slin_2432 Slin_2432 glmS glmS Slin_2902 Slin_2902 Slin_2994 Slin_2994 Slin_4155 Slin_4155 Slin_4403 Slin_4403 Slin_4408 Slin_4408 glmS-2 glmS-2 Slin_5132 Slin_5132 Slin_5139 Slin_5139 Slin_5432 Slin_5432 Slin_5523 Slin_5523 Slin_5648 Slin_5648 carA carA Slin_5955 Slin_5955 Slin_5971 Slin_5971 Slin_6239 Slin_6239 purQ purQ
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pyrBTIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: hypothetical protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa)
argHTIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mxa:MXAN_5107 argininosuccinate lyase. (445 aa)
Slin_0407PFAM: argininosuccinate synthase; Queuosine synthesis-like; KEGG: mxa:MXAN_5108 argininosuccinate synthase. (400 aa)
Slin_0568PFAM: asparagine synthase; KEGG: mlo:mll5256 asparagine synthetase. (647 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)
Slin_1914PFAM: aminotransferase class I and II; KEGG: pfs:PFLU1731 putative aminotransferase. (403 aa)
Slin_2233L-asparaginase, type I; KEGG: hypothetical protein; K01424 L-asparaginase; TIGRFAM: L-asparaginase, type I; PFAM: Asparaginase/glutaminase. (379 aa)
Slin_2319PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: vvu:VV1_0553 glutamate synthase, large subunit. (1524 aa)
Slin_2320TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vcj:VCD_001976 glutamate synthase [NADPH] small chain. (496 aa)
Slin_2431PFAM: glutamine synthetase catalytic region; KEGG: ppd:Ppro_1682 glutamine synthetase, catalytic region. (729 aa)
Slin_2432Glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: mrd:Mrad2831_5128 glutamate--ammonia ligase. (344 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (612 aa)
Slin_2902KEGG: dvl:Dvul_2381 alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; Belongs to the AlaDH/PNT family. (376 aa)
Slin_2994PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rsp:RSP_0723 L-alanine dehydrogenase. (403 aa)
Slin_4155Beta-aspartyl-peptidase; PFAM: peptidase T2 asparaginase 2; KEGG: ent:Ent638_1322 L-asparaginase. (306 aa)
Slin_4403PFAM: aminotransferase class I and II; KEGG: mno:Mnod_1959 aminotransferase class I and II. (405 aa)
Slin_4408PFAM: Aldehyde Dehydrogenase; KEGG: tgr:Tgr7_0333 aldehyde dehydrogenase. (457 aa)
glmS-2Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (612 aa)
Slin_5132L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (528 aa)
Slin_5139Glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; KEGG: mxa:MXAN_5630 glutamine synthetase family protein. (457 aa)
Slin_5432PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: similar to Nitrilase homolog 1. (273 aa)
Slin_5523TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: dat:HRM2_16880 PutA2; Belongs to the aldehyde dehydrogenase family. (543 aa)
Slin_5648PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: ppd:Ppro_1713 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (424 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: vpa:VP0470 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (367 aa)
Slin_5955KEGG: purB; adenylosuccinate lyase; K01756 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (446 aa)
Slin_5971Amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; KEGG: aci:ACIAD1323 amidophosphoribosyltransferase. (630 aa)
Slin_6239TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: tcx:Tcr_0879 carbamoyl-phosphate synthase, large subunit. (958 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (228 aa)
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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