STRINGSTRING
uppP uppP Slin_1108 Slin_1108 Slin_2266 Slin_2266 Slin_2717 Slin_2717 mtgA mtgA Slin_2918 Slin_2918 Slin_3074 Slin_3074 Slin_3202 Slin_3202 Slin_3220 Slin_3220 murF murF Slin_4433 Slin_4433 Slin_4738 Slin_4738 murE murE mraY mraY murD murD murG murG murC murC Slin_5076 Slin_5076 murB murB Slin_5444 Slin_5444 murA murA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
uppPUndecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (281 aa)
Slin_1108D-alanine--D-alanine ligase domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (551 aa)
Slin_2266Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (835 aa)
Slin_2717D-alanyl-D-alaninecarboxypeptidase/ D-alanyl-D-alanine-endopeptidase; KEGG: pfs:PFLU1023 putative penicillin-binding exported protein; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D- alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C. (514 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (222 aa)
Slin_2918PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: bba:Bd2432 hypothetical protein. (191 aa)
Slin_3074PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: dia:Dtpsy_1674 peptidoglycan glycosyltransferase. (854 aa)
Slin_3202Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: gur:Gura_2858 peptidoglycan glycosyltransferase. (654 aa)
Slin_3220PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase; KEGG: cti:RALTA_B1852 peptidoglycan glycosyltransferase. (785 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/ D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (449 aa)
Slin_4433Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (245 aa)
Slin_4738KEGG: pca:Pcar_2208 peptidoglycan synthetase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. (709 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (498 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (402 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (449 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (370 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (461 aa)
Slin_5076TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; Penicillin- binding domain protein; penicillin-binding protein transpeptidase; KEGG: mxa:MXAN_2419 penicillin-binding protein 1C. (816 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (341 aa)
Slin_5444PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; KEGG: son:SO_2394 penicillin-binding protein 4. (400 aa)
murAUDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (435 aa)
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale DSM 74, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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