STRINGSTRING
dapB dapB argG argG asd asd AEI05140.1 AEI05140.1 argJ argJ AEI05182.1 AEI05182.1 AEI05327.1 AEI05327.1 dapE dapE dapD dapD AEI05330.1 AEI05330.1 argB argB AEI05394.1 AEI05394.1 metH metH metF metF AEI05484.1 AEI05484.1 AEI05485.1 AEI05485.1 thrB thrB proC proC gdh gdh AEI05776.1 AEI05776.1 putA putA metE metE patA patA cysS cysS cysK1 cysK1 cysK2 cysK2 metC metC hom hom AEI06718.1 AEI06718.1 argC argC glnA glnA AEI06829.1 AEI06829.1 AEI06830.1 AEI06830.1 dapA2 dapA2 cysE cysE ahcY ahcY metK metK gltB gltB gltD gltD AEI07854.1 AEI07854.1 metX metX lysA lysA argH argH thrC thrC metZ metZ argF argF argD argD proB proB proA proA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dapBDihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (272 aa)
argGArgininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (445 aa)
asdAspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
AEI05140.1Aspartate kinase; Belongs to the aspartokinase family. (418 aa)
argJArginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (417 aa)
AEI05182.1Glutamate synthase domain protein; Belongs to the glutamate synthase family. (539 aa)
AEI05327.1Putative nucleoside phosphorylase. (186 aa)
dapESuccinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (384 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD. (281 aa)
AEI05330.1Pyrimidine 5'-nucleotidase. (245 aa)
argBAcetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa)
AEI05394.1Methyltransferase. (505 aa)
metHMethionine synthase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1286 aa)
metF5,10-methylenetetrahydrofolate reductase MetF; Belongs to the methylenetetrahydrofolate reductase family. (301 aa)
AEI05484.1Diaminopropionate ammonia-lyase. (406 aa)
AEI05485.1Peptidase M20 family protein. (406 aa)
thrBHomoserine kinase ThrB; Belongs to the pseudomonas-type ThrB family. (326 aa)
proCPyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (277 aa)
gdhNADP-specific glutamate dehydrogenase Gdh; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
AEI05776.1Putative hydrolase/acyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (352 aa)
putABifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1234 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase MetE; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (787 aa)
patAPutrescine aminotransferase PatA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (466 aa)
cysScysteine-tRNA ligase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (464 aa)
cysK1Cysteine synthase CysK; Belongs to the cysteine synthase/cystathionine beta- synthase family. (326 aa)
cysK2Cysteine synthase CysK. (345 aa)
metCCystathionine beta-lyase MetC. (399 aa)
homHomoserine dehydrogenase Hom. (438 aa)
AEI06718.1Aminotransferase. (405 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (352 aa)
glnAGlutamate-ammonia ligase GlnA. (469 aa)
AEI06829.1Putative CoA-binding protein. (204 aa)
AEI06830.1O-acetylhomoserine/O-acetylserine sulfhydrylase. (426 aa)
dapA2Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (378 aa)
cysESerine acetyltransferase CysE. (274 aa)
ahcYAdenosylhomocysteinase AhcY; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (472 aa)
metKS-adenosylmethionine synthase MetK; Belongs to the AdoMet synthase family. (397 aa)
gltBGlutamate synthase large subunit. (1588 aa)
gltDGlutamate synthase NADH/NADPH, small subunit GltD. (485 aa)
AEI07854.1Methionine biosynthesis MetW. (217 aa)
metXHomoserine O-acetyltransferase MetX; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (402 aa)
lysADiaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa)
argHArgininosuccinate lyase ArgH. (465 aa)
thrCThreonine synthase ThrC. (471 aa)
metZO-succinylhomoserine sulfhydrylase MetZ; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (403 aa)
argFOrnithine carbamoyltransferase ArgF; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (311 aa)
argDAcetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (407 aa)
proBGlutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (397 aa)
proAGamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (428 aa)
Your Current Organism:
Oligotropha carboxidovorans
NCBI taxonomy Id: 504832
Other names: O. carboxidovorans OM5, Oligotropha carboxidovorans OM5, Oligotropha carboxidovorans str. OM5, Oligotropha carboxidovorans strain OM5
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