STRINGSTRING
AEI06141.1 AEI06141.1 gyrB gyrB addA addA AEI04858.1 AEI04858.1 AEI04931.1 AEI04931.1 AEI05082.1 AEI05082.1 AEI05088.1 AEI05088.1 AEI05091.1 AEI05091.1 AEI05093.1 AEI05093.1 AEI05199.1 AEI05199.1 ruvA ruvA ruvB ruvB AEI05700.1 AEI05700.1 smc smc AEI06277.1 AEI06277.1 dnaB dnaB gyrA gyrA recG recG mfd mfd AEI06572.1 AEI06572.1 AEI06593.1 AEI06593.1 parE parE AEI06808.1 AEI06808.1 parC parC topA topA AEI07131.1 AEI07131.1 AEI07134.1 AEI07134.1 uvrD uvrD AEI07594.1 AEI07594.1 AEI07633.1 AEI07633.1 priA priA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEI06141.1Putative ATPase. (550 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (812 aa)
addADouble-strand break repair helicase AddA; Belongs to the helicase family. UvrD subfamily. (1161 aa)
AEI04858.1Mg chelatase-like protein. (512 aa)
AEI04931.1Hypothetical protein. (427 aa)
AEI05082.1DNA helicase, UvrD/Rep family protein. (567 aa)
AEI05088.1Hypothetical protein. (535 aa)
AEI05091.1Putative DNA helicase. (1030 aa)
AEI05093.1Hypothetical protein. (651 aa)
AEI05199.1Hypothetical protein. (669 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
ruvBHolliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (346 aa)
AEI05700.1Hypothetical protein. (416 aa)
smcChromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1154 aa)
AEI06277.1Hypothetical protein. (592 aa)
dnaBReplicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (498 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (905 aa)
recGATP-dependent DNA helicase RecG. (704 aa)
mfdTranscription-repair-coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1171 aa)
AEI06572.1Putative ATPase, RecA family protein. (621 aa)
AEI06593.1Hypothetical protein. (411 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (689 aa)
AEI06808.1Histone-like DNA-binding protein; Belongs to the bacterial histone-like protein family. (99 aa)
parCDNA topoisomerase 4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (751 aa)
topADNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (913 aa)
AEI07131.1Hypothetical protein. (567 aa)
AEI07134.1Putative helicase. (577 aa)
uvrDDNA helicase II. (857 aa)
AEI07594.1Hypothetical protein. (255 aa)
AEI07633.1Histone-like DNA-binding protein; Belongs to the bacterial histone-like protein family. (99 aa)
priAPrimosomal assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (743 aa)
Your Current Organism:
Oligotropha carboxidovorans
NCBI taxonomy Id: 504832
Other names: O. carboxidovorans OM5, Oligotropha carboxidovorans OM5, Oligotropha carboxidovorans str. OM5, Oligotropha carboxidovorans strain OM5
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