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accD accD acsA acsA AEI04976.1 AEI04976.1 AEI05098.1 AEI05098.1 phbA phbA gloB gloB accA accA pckA pckA fadA1 fadA1 glcB glcB AEI05489.1 AEI05489.1 lldD lldD AEI05726.1 AEI05726.1 AEI05734.1 AEI05734.1 prpB prpB ppdK ppdK AEI05882.1 AEI05882.1 AEI05925.1 AEI05925.1 AEI05927.1 AEI05927.1 AEI05970.1 AEI05970.1 AEI06043.1 AEI06043.1 AEI06128.1 AEI06128.1 ttuE ttuE AEI06224.1 AEI06224.1 maeA maeA pdhA pdhA pdhB pdhB pdhC pdhC lpd1 lpd1 AEI06555.1 AEI06555.1 AEI06704.1 AEI06704.1 AEI06751.1 AEI06751.1 AEI06752.1 AEI06752.1 AEI06831.1 AEI06831.1 AEI06971.1 AEI06971.1 AEI07261.1 AEI07261.1 fumA fumA ppc ppc leuA leuA fumC fumC dld dld fadA2 fadA2 pyk pyk cobZ cobZ AEI07658.1 AEI07658.1 ackA ackA pta pta AEI07873.1 AEI07873.1 lpd2 lpd2 mdh mdh
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (318 aa)
acsAAcetate-coenzyme A ligase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
AEI04976.1Glyoxalase/bleomycin resistance. (136 aa)
AEI05098.1Putative hydrolase. (223 aa)
phbAacetyl-CoA acetyltransferase PhbA; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
gloBHydroxyacylglutathione hydrolase GloB; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (255 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (538 aa)
fadA13-ketoacyl-CoA thiolase FadA; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (720 aa)
AEI05489.1Putative acyl-CoA synthase. (457 aa)
lldDL-lactate dehydrogenase LldD. (383 aa)
AEI05726.1Transketolase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (803 aa)
AEI05734.1Hypothetical protein. (645 aa)
prpBMethylisocitrate lyase PrpB; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (303 aa)
ppdKPyruvate, phosphate dikinase PpdK. (981 aa)
AEI05882.1Putative beta-lactamase. (309 aa)
AEI05925.1Putative malonate decarboxylase, alpha. (556 aa)
AEI05927.1Putative malonate decarboxylase, beta subunit. (295 aa)
AEI05970.1acyl-CoA synthase. (898 aa)
AEI06043.1Phosphate acetyl/butaryl transferase family. (304 aa)
AEI06128.1Hypothetical protein. (612 aa)
ttuEPyruvate kinase TtuE; Belongs to the pyruvate kinase family. (469 aa)
AEI06224.1CoA-binding domain protein. (710 aa)
maeANAD-dependent malic enzyme MaeA. (771 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (339 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (467 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (457 aa)
lpd1Dihydrolipoyl dehydrogenase Lpd. (473 aa)
AEI06555.1Hypothetical protein. (287 aa)
AEI06704.1Glyoxalase/bleomycin resistance. (149 aa)
AEI06751.1Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (166 aa)
AEI06752.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
AEI06831.1Hypothetical protein. (269 aa)
AEI06971.1Acylphosphatase. (99 aa)
AEI07261.1Glyoxalase/bleomycin resistance. (137 aa)
fumAFumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)
ppcPhosphoenolpyruvate carboxylase Ppc; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (943 aa)
leuA2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (519 aa)
fumCFumarate hydratase class II 1; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa)
dldD-lactate dehydrogenase. (469 aa)
fadA2acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
pykPyruvate kinase Pyk; Belongs to the pyruvate kinase family. (478 aa)
cobZPrecorrin 3B synthase CobZ, cobalamin biosynthesis; Vitamin B12 biosynthesis. (463 aa)
AEI07658.1Thiolase domain protein. (389 aa)
ackAAcetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
ptaPhosphate acetyltransferase Pta. (475 aa)
AEI07873.1Putative 3-demethylubiquinone-9 3-methyltransferase. (140 aa)
lpd2Dihydrolipoyl dehydrogenase Lpd. (467 aa)
mdhMalate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (322 aa)
Your Current Organism:
Oligotropha carboxidovorans
NCBI taxonomy Id: 504832
Other names: O. carboxidovorans OM5, Oligotropha carboxidovorans OM5, Oligotropha carboxidovorans str. OM5, Oligotropha carboxidovorans strain OM5
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