STRINGSTRING
thiO2 thiO2 nsrR nsrR AEI07469.1 AEI07469.1 thiD thiD adk adk thiL thiL nifS nifS AEI06611.1 AEI06611.1 AEI06450.1 AEI06450.1 AEI06320.1 AEI06320.1 dxs2 dxs2 dxs1 dxs1 thiO1 thiO1 thiG thiG thiE2 thiE2 thiC thiC thiE1 thiE1 AEI07872.1 AEI07872.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thiO2Thiamine biosynthesis oxidoreductase ThiO. (367 aa)
nsrRHTH-type transcriptional regulator. (149 aa)
AEI07469.1TenA/Thi-4 family protein. (223 aa)
thiDHydroxymethylpyrimidine/phosphomethylpyrimidine kinase ThiD. (266 aa)
adkAdenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (350 aa)
thiLThiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (323 aa)
nifSCysteine desulfurase NifS. (385 aa)
AEI06611.1Hypothetical protein. (175 aa)
AEI06450.1Hypothetical protein. (110 aa)
AEI06320.1TenA/Thi-4 family protein. (220 aa)
dxs21-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
dxs11-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (636 aa)
thiO1Putative thiamine biosynthesis oxidoreductase ThiO. (349 aa)
thiGThiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (262 aa)
thiE2Thiamine-phosphate pyrophosphorylase ThiE. (202 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (632 aa)
thiE1Thiamine-phosphate pyrophosphorylase ThiE. (229 aa)
AEI07872.1Hypothetical protein, DUF1428 family. (119 aa)
Your Current Organism:
Oligotropha carboxidovorans
NCBI taxonomy Id: 504832
Other names: O. carboxidovorans OM5, Oligotropha carboxidovorans OM5, Oligotropha carboxidovorans str. OM5, Oligotropha carboxidovorans strain OM5
Server load: medium (44%) [HD]