STRINGSTRING
AEI07911.1 AEI07911.1 coaBC coaBC ilvD1 ilvD1 coaA coaA coaE coaE AEI05271.1 AEI05271.1 ilvE ilvE AEI05733.1 AEI05733.1 cutA cutA AEI06093.1 AEI06093.1 AEI06218.1 AEI06218.1 AEI06300.1 AEI06300.1 panB panB ilvD2 ilvD2 coaD coaD AEI06569.1 AEI06569.1 AEI06590.1 AEI06590.1 mazG mazG ilvD3 ilvD3 acpS acpS panC panC AEI07158.1 AEI07158.1 AEI07366.1 AEI07366.1 ilvC ilvC ilvH ilvH AEI07444.1 AEI07444.1 panE panE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEI07911.1Hypothetical protein. (360 aa)
coaBCCoenzyme A biosynthesis bifunctional protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (474 aa)
ilvD1Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (613 aa)
coaAPantothenate kinase CoaA. (318 aa)
coaEdephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (199 aa)
AEI05271.1Putative integrase; Belongs to the 'phage' integrase family. (417 aa)
ilvEBranched-chain-amino-acid aminotransferase IlvE. (370 aa)
AEI05733.1Putative 2-dehydropantoate 2-reductase. (337 aa)
cutAPutative divalent ion tolerance protein CutA. (105 aa)
AEI06093.1Hypothetical protein. (356 aa)
AEI06218.1Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (339 aa)
AEI06300.1Integrase; Belongs to the 'phage' integrase family. (419 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (276 aa)
ilvD2Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (574 aa)
coaDPhosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa)
AEI06569.1Phage integrase; Belongs to the 'phage' integrase family. (390 aa)
AEI06590.1Phage integrase; Belongs to the 'phage' integrase family. (405 aa)
mazGNTP pyrophosphohydrolase MazG. (276 aa)
ilvD3Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (558 aa)
acpSHolo-[acyl-carrier-protein] synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (137 aa)
panCPantoate-beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
AEI07158.1Putative integrase; Belongs to the 'phage' integrase family. (404 aa)
AEI07366.1Hypothetical protein. (355 aa)
ilvCKetol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
ilvHAcetolactate synthase small subunit IlvH. (185 aa)
AEI07444.1Branched-chain-amino-acid aminotransferase. (268 aa)
panE2-dehydropantoate 2-reductase PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (302 aa)
Your Current Organism:
Oligotropha carboxidovorans
NCBI taxonomy Id: 504832
Other names: O. carboxidovorans OM5, Oligotropha carboxidovorans OM5, Oligotropha carboxidovorans str. OM5, Oligotropha carboxidovorans strain OM5
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