(11 nodes) Pre-replicative complex assembly, and Mitotic DNA replication preinitiation complex assembly network (Penicillium griseofulvum)

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second shell of interactors

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Your Input:
	PGRI_045710	Protein kinase domain-containing protein. (472 aa)
	PGRI_052390	CDC45 family. (849 aa)
	PGRI_054920	DNA helicase; Belongs to the MCM family. (896 aa)
	PGRI_015290	Cell division control protein; Belongs to the CDC6/cdc18 family. (640 aa)
	PGRI_019450	Regulatory subunit Dfp1/Him1, central region. (649 aa)
	PGRI_028110	Zinc finger, Mcm10/DnaG-type. (800 aa)
	PGRI_055330	DNA helicase; Belongs to the MCM family. (719 aa)
	PGRI_005380	DNA helicase; Belongs to the MCM family. (956 aa)
	PGRI_006980	DNA helicase; Belongs to the MCM family. (953 aa)
	PGRI_010150	DNA helicase; Belongs to the MCM family. (953 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (811 aa)

Your Current Organism:

Penicillium griseofulvum

NCBI taxonomy Id: 5078
Other names: CBS 185.27, P. griseofulvum, Penicillium patulum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	PGRI_005380	A0A135LYN8	A0A135LWZ7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PGRI_006980	A0A135LYN8	A0A135LXG0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PGRI_010150	A0A135LYN8	A0A135LYF0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PGRI_015290	A0A135LYN8	A0A135LFB2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.999
MCM7	PGRI_019450	A0A135LYN8	A0A135LGK0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Regulatory subunit Dfp1/Him1, central region.	0.990
MCM7	PGRI_028110	A0A135LYN8	A0A135LIY5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Zinc finger, Mcm10/DnaG-type.	0.996
MCM7	PGRI_045710	A0A135LYN8	A0A135L9P9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Protein kinase domain-containing protein.	0.993
MCM7	PGRI_052390	A0A135LYN8	A0A135LBP6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	CDC45 family.	0.999
MCM7	PGRI_054920	A0A135LYN8	A0A135LCE9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PGRI_055330	A0A135LYN8	A0A135LKQ5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
PGRI_005380	MCM7	A0A135LWZ7	A0A135LYN8	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
PGRI_005380	PGRI_006980	A0A135LWZ7	A0A135LXG0	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGRI_005380	PGRI_010150	A0A135LWZ7	A0A135LYF0	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGRI_005380	PGRI_015290	A0A135LWZ7	A0A135LFB2	DNA helicase; Belongs to the MCM family.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.999
PGRI_005380	PGRI_019450	A0A135LWZ7	A0A135LGK0	DNA helicase; Belongs to the MCM family.	Regulatory subunit Dfp1/Him1, central region.	0.994
PGRI_005380	PGRI_028110	A0A135LWZ7	A0A135LIY5	DNA helicase; Belongs to the MCM family.	Zinc finger, Mcm10/DnaG-type.	0.996
PGRI_005380	PGRI_045710	A0A135LWZ7	A0A135L9P9	DNA helicase; Belongs to the MCM family.	Protein kinase domain-containing protein.	0.998
PGRI_005380	PGRI_052390	A0A135LWZ7	A0A135LBP6	DNA helicase; Belongs to the MCM family.	CDC45 family.	0.999
PGRI_005380	PGRI_054920	A0A135LWZ7	A0A135LCE9	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
PGRI_005380	PGRI_055330	A0A135LWZ7	A0A135LKQ5	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999