74 items (Penicillium griseofulvum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGRI_024440	Sodium/calcium exchanger membrane region; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (706 aa)
	PGRI_025220	Uncharacterized protein. (441 aa)
	PGRI_025370	Uncharacterized protein. (292 aa)
	PGRI_026190	Armadillo-like helical. (1437 aa)
	PGRI_026290	Uncharacterized protein. (398 aa)
	PGRI_026650	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1187 aa)
	PGRI_027410	Tetratricopeptide-like helical. (1280 aa)
	PGRI_028040	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (878 aa)
	PGRI_029720	Dehydrogenase, multihelical. (308 aa)
	PGRI_031160	Gtr1/RagA G protein. (303 aa)
	PGRI_071090	Patched. (1251 aa)
	PGRI_055450	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1101 aa)
	PGRI_057350	Zn(2)-C6 fungal-type domain-containing protein. (475 aa)
	PGRI_057260	Uncharacterized protein. (374 aa)
	PGRI_060760	Gtr1/RagA G protein. (337 aa)
	PGRI_060810	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (689 aa)
	PGRI_061360	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (699 aa)
	PGRI_044270	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2. (1247 aa)
	PGRI_063510	Ubiquitin-conjugating enzyme, E2. (139 aa)
	PGRI_063950	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (855 aa)
	PGRI_064500	Alkaline phosphatase-like, alpha/beta/alpha; Belongs to the alkaline phosphatase family. (664 aa)
	PGRI_064710	Snf7. (216 aa)
	PGRI_068000	Uncharacterized protein family UPF0220. (173 aa)
	PGRI_094370	V-type ATP synthase catalytic subunit A/alpha. (601 aa)
	PGRI_094380	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (694 aa)
	PGRI_089580	DUF202 domain-containing protein. (126 aa)
	PGRI_083580	Cation efflux protein. (526 aa)
	PGRI_083690	DUF202 domain-containing protein. (226 aa)
	PGRI_086550	Amino acid transporter, transmembrane. (626 aa)
	PGRI_087350	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1. (971 aa)
	PGRI_040690	Zinc finger, FYVE/PHD-type. (2503 aa)
	PGRI_041910	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (332 aa)
	PGRI_033380	Nitrogen permease regulator 3. (812 aa)
	PGRI_046320	Small GTPase superfamily, Rho type. (201 aa)
	PGRI_046610	Uncharacterized protein. (280 aa)
	PGRI_046840	Glycoside hydrolase/deacetylase, beta/alpha-barrel. (1092 aa)
	PGRI_046860	Ctr copper transporter. (194 aa)
	PGRI_088300	Uncharacterized protein. (925 aa)
	PGRI_079130	SPX domain-containing protein. (788 aa)
	PGRI_079480	SAC domain-containing protein. (1003 aa)
	PGRI_080220	E3 ubiquitin-protein ligase PEP5. (956 aa)
	PGRI_000420	Uncharacterized protein. (311 aa)
	PGRI_002480	Uncharacterized protein. (966 aa)
	PGRI_003410	Uncharacterized protein. (599 aa)
	PGRI_005480	Major facilitator superfamily domain, general substrate transporter. (436 aa)
	PGRI_005720	Leucine-rich repeat, typical subtype. (801 aa)
	PGRI_006240	Nitrogen permease regulator 2. (548 aa)
	PGRI_006490	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (449 aa)
	PGRI_007850	NAD_binding_2 domain-containing protein. (920 aa)
	PGRI_008390	Amino acid transporter, transmembrane. (747 aa)
	PGRI_008560	Major facilitator superfamily domain, general substrate transporter. (869 aa)
	PGRI_009540	Sodium/calcium exchanger membrane region; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1059 aa)
	PGRI_075120	Zinc finger, RING-type. (1412 aa)
	PGRI_075130	Ubiquitin-conjugating enzyme, E2; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	PGRI_075520	ATPase, V1/A1 complex, subunit E. (231 aa)
	PGRI_077340	Zinc/iron permease. (497 aa)
	PGRI_077760	DUF202 domain-containing protein. (235 aa)
	PGRI_078180	Vacuolar segregation subunit 7. (896 aa)
	PGRI_078570	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (461 aa)
	PGRI_051610	Dehydrogenase, multihelical. (315 aa)
	PGRI_052630	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1429 aa)
	PGRI_053970	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family. (365 aa)
	PGRI_054240	Uncharacterized protein. (628 aa)
	PGRI_035390	Armadillo-like helical. (922 aa)
	PGRI_039230	Alkaline phosphatase. (868 aa)
	PGRI_012720	Small GTPase superfamily, Rab type. (187 aa)
	PGRI_012930	V-type ATPase subunit D. (287 aa)
	PGRI_015430	Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB. (638 aa)
	PGRI_016360	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (438 aa)
	PGRI_015850	Armadillo. (578 aa)
	PGRI_016370	Sodium/calcium exchanger membrane region; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (253 aa)
	PGRI_016380	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (407 aa)
	PGRI_017920	Major facilitator superfamily domain, general substrate transporter. (392 aa)
	PGRI_022240	PI3K/PI4K domain-containing protein. (770 aa)

Your Current Organism:

Penicillium griseofulvum

NCBI taxonomy Id: 5078
Other names: CBS 185.27, P. griseofulvum, Penicillium patulum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGRI_002480	PGRI_040690	A0A135LW49	A0A135L870	Uncharacterized protein.	Zinc finger, FYVE/PHD-type.	0.984
PGRI_002480	PGRI_078180	A0A135LW49	A0A135M0D0	Uncharacterized protein.	Vacuolar segregation subunit 7.	0.596
PGRI_002480	PGRI_079480	A0A135LW49	A0A135LUP8	Uncharacterized protein.	SAC domain-containing protein.	0.981
PGRI_003410	PGRI_012930	A0A135LWK1	A0A135LEN2	Uncharacterized protein.	V-type ATPase subunit D.	0.703
PGRI_003410	PGRI_035390	A0A135LWK1	A0A135LCU9	Uncharacterized protein.	Armadillo-like helical.	0.686
PGRI_003410	PGRI_053970	A0A135LWK1	A0A135LC42	Uncharacterized protein.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family.	0.787
PGRI_003410	PGRI_063950	A0A135LWK1	A0A135LPE2	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.828
PGRI_003410	PGRI_075520	A0A135LWK1	A0A135LZK9	Uncharacterized protein.	ATPase, V1/A1 complex, subunit E.	0.703
PGRI_003410	PGRI_094370	A0A135LWK1	A0A135LR22	Uncharacterized protein.	V-type ATP synthase catalytic subunit A/alpha.	0.761
PGRI_005720	PGRI_026190	A0A135LX22	A0A135LII0	Leucine-rich repeat, typical subtype.	Armadillo-like helical.	0.472
PGRI_005720	PGRI_031160	A0A135LX22	A0A135LJT8	Leucine-rich repeat, typical subtype.	Gtr1/RagA G protein.	0.420
PGRI_005720	PGRI_046320	A0A135LX22	A0A135L9Y8	Leucine-rich repeat, typical subtype.	Small GTPase superfamily, Rho type.	0.590
PGRI_005720	PGRI_060760	A0A135LX22	A0A135LMC2	Leucine-rich repeat, typical subtype.	Gtr1/RagA G protein.	0.526
PGRI_005720	PGRI_063510	A0A135LX22	A0A135LPC2	Leucine-rich repeat, typical subtype.	Ubiquitin-conjugating enzyme, E2.	0.520
PGRI_005720	PGRI_064710	A0A135LX22	A0A135LPR5	Leucine-rich repeat, typical subtype.	Snf7.	0.539
PGRI_005720	PGRI_075130	A0A135LX22	A0A135LZI4	Leucine-rich repeat, typical subtype.	Ubiquitin-conjugating enzyme, E2; Belongs to the ubiquitin-conjugating enzyme family.	0.559
PGRI_006240	PGRI_026190	A0A135LX82	A0A135LII0	Nitrogen permease regulator 2.	Armadillo-like helical.	0.789
PGRI_006240	PGRI_031160	A0A135LX82	A0A135LJT8	Nitrogen permease regulator 2.	Gtr1/RagA G protein.	0.969
PGRI_006240	PGRI_033380	A0A135LX82	A0A135L9C6	Nitrogen permease regulator 2.	Nitrogen permease regulator 3.	0.997
PGRI_006240	PGRI_053970	A0A135LX82	A0A135LC42	Nitrogen permease regulator 2.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family.	0.629