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PGRI_063020 PGRI_063020 PGRI_032780 PGRI_032780 PGRI_071220 PGRI_071220 PGRI_070710 PGRI_070710 PGRI_055560 PGRI_055560 PGRI_057760 PGRI_057760 PGRI_057580 PGRI_057580 PGRI_058790 PGRI_058790 PGRI_058990 PGRI_058990 PGRI_059290 PGRI_059290 PGRI_059260 PGRI_059260 PGRI_060100 PGRI_060100 PGRI_061170 PGRI_061170 PGRI_061720 PGRI_061720 PGRI_061860 PGRI_061860 ADI1 ADI1 PGRI_043390 PGRI_043390 PGRI_043880 PGRI_043880 PGRI_044450 PGRI_044450 PGRI_044830 PGRI_044830 PGRI_063440 PGRI_063440 PGRI_063890 PGRI_063890 PGRI_064000 PGRI_064000 PGRI_064320 PGRI_064320 PGRI_064310 PGRI_064310 PGRI_064610 PGRI_064610 PGRI_066430 PGRI_066430 PGRI_067570 PGRI_067570 PGRI_068070 PGRI_068070 PGRI_067930 PGRI_067930 PGRI_095190 PGRI_095190 PGRI_095440 PGRI_095440 PGRI_095420 PGRI_095420 PGRI_094260 PGRI_094260 PGRI_094490 PGRI_094490 PGRI_089670 PGRI_089670 PGRI_082840 PGRI_082840 PGRI_083220 PGRI_083220 PGRI_083660 PGRI_083660 PGRI_083550 PGRI_083550 PGRI_083650 PGRI_083650 PGRI_084630 PGRI_084630 PGRI_085910 PGRI_085910 PGRI_085640 PGRI_085640 PGRI_085400 PGRI_085400 PGRI_085550 PGRI_085550 PGRI_086570 PGRI_086570 PGRI_086710 PGRI_086710 PGRI_086490 PGRI_086490 PGRI_087970 PGRI_087970 PGRI_088310 PGRI_088310 PGRI_088290 PGRI_088290 PGRI_088510 PGRI_088510 PGRI_079030 PGRI_079030 PGRI_079210 PGRI_079210 PGRI_080730 PGRI_080730 PGRI_081640 PGRI_081640 PGRI_081940 PGRI_081940 PGRI_000650 PGRI_000650 MDE1 MDE1 PGRI_001610 PGRI_001610 PGRI_002430 PGRI_002430 PGRI_003230 PGRI_003230 PGRI_003280 PGRI_003280 PGRI_004080 PGRI_004080 PGRI_004030 PGRI_004030 PGRI_004040 PGRI_004040 PGRI_006610 PGRI_006610 PGRI_007930 PGRI_007930 PGRI_009240 PGRI_009240 PGRI_009340 PGRI_009340 PGRI_009360 PGRI_009360 PGRI_009760 PGRI_009760 PGRI_071690 PGRI_071690 PGRI_072520 PGRI_072520 PGRI_072150 PGRI_072150 PGRI_072550 PGRI_072550 PGRI_073700 PGRI_073700 PGRI_073890 PGRI_073890 PGRI_074260 PGRI_074260 PGRI_074600 PGRI_074600 PGRI_075180 PGRI_075180 PGRI_075090 PGRI_075090 PGRI_076610 PGRI_076610 PGRI_077200 PGRI_077200 PGRI_077520 PGRI_077520 PGRI_078580 PGRI_078580 PGRI_078610 PGRI_078610 PGRI_078390 PGRI_078390 PGRI_078790 PGRI_078790 PGRI_095820 PGRI_095820 PGRI_041660 PGRI_041660 PGRI_042230 PGRI_042230 MRI1 MRI1 PGRI_040570 PGRI_040570 PGRI_045590 PGRI_045590 MET3 MET3 PGRI_047380 PGRI_047380 PGRI_048540 PGRI_048540 PGRI_048980 PGRI_048980 PGRI_048620 PGRI_048620 PGRI_049270 PGRI_049270 PGRI_049600 PGRI_049600 PGRI_049260 PGRI_049260 PGRI_051120 PGRI_051120 PGRI_051690 PGRI_051690 PGRI_051770 PGRI_051770 PGRI_051650 PGRI_051650 PGRI_051160 PGRI_051160 PGRI_053570 PGRI_053570 PGRI_054630 PGRI_054630 PGRI_054620 PGRI_054620 PGRI_039280 PGRI_039280 PGRI_034720 PGRI_034720 PGRI_035110 PGRI_035110 PGRI_035620 PGRI_035620 PGRI_035810 PGRI_035810 PGRI_036520 PGRI_036520 PGRI_036750 PGRI_036750 PGRI_037830 PGRI_037830 PGRI_038150 PGRI_038150 PGRI_038080 PGRI_038080 PGRI_038760 PGRI_038760 PGRI_011470 PGRI_011470 PGRI_011940 PGRI_011940 PGRI_014350 PGRI_014350 PGRI_014910 PGRI_014910 PGRI_014850 PGRI_014850 PGRI_015300 PGRI_015300 PGRI_015970 PGRI_015970 PGRI_016530 PGRI_016530 PGRI_017240 PGRI_017240 PGRI_018030 PGRI_018030 PGRI_018580 PGRI_018580 PGRI_018750 PGRI_018750 PGRI_018960 PGRI_018960 PGRI_020160 PGRI_020160 PGRI_021770 PGRI_021770 PGRI_021900 PGRI_021900 PGRI_022430 PGRI_022430 PGRI_023890 PGRI_023890 PGRI_024170 PGRI_024170 PGRI_025790 PGRI_025790 PGRI_026430 PGRI_026430 PGRI_028070 PGRI_028070 PGRI_030040 PGRI_030040 PGRI_030760 PGRI_030760 PGRI_030590 PGRI_030590 PGRI_030980 PGRI_030980
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGRI_063020Pyridoxal phosphate-dependent transferase, major region, subdomain 2. (764 aa)
PGRI_032780FtsJ domain-containing protein. (374 aa)
PGRI_071220D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
PGRI_070710Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (478 aa)
PGRI_055560Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (691 aa)
PGRI_057760Homoserine acetyltransferase. (499 aa)
PGRI_057580Glutamine amidotransferase type 1. (453 aa)
PGRI_058790Homoserine acetyltransferase. (527 aa)
PGRI_058990Pyridoxal phosphate-dependent transferase, major region, subdomain 2. (517 aa)
PGRI_059290Vitamin B6 biosynthesis protein; Belongs to the PdxS/SNZ family. (305 aa)
PGRI_059260Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (459 aa)
PGRI_060100Homocysteine S-methyltransferase. (345 aa)
PGRI_061170Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
PGRI_0617201-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (256 aa)
PGRI_061860Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (314 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (177 aa)
PGRI_043390Aminoglycoside phosphotransferase. (353 aa)
PGRI_043880Histidine biosynthesis trifunctional protein. (868 aa)
PGRI_044450Aminotransferase, class I/classII. (557 aa)
PGRI_0448303-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1578 aa)
PGRI_063440Glycosyl transferase, family 3. (440 aa)
PGRI_063890Asparagine synthase. (602 aa)
PGRI_064000Saccharopine dehydrogenase / Homospermidine synthase. (449 aa)
PGRI_064320Uncharacterized protein. (627 aa)
PGRI_064310Aromatic amino acid beta-eliminating lyase/threonine aldolase. (361 aa)
PGRI_064610Peptidase M20. (754 aa)
PGRI_066430Major facilitator superfamily domain, general substrate transporter. (781 aa)
PGRI_067570Phosphoserine aminotransferase. (444 aa)
PGRI_068070Imidazoleglycerol-phosphate dehydratase. (244 aa)
PGRI_067930Glutamine amidotransferase type 1. (804 aa)
PGRI_095190Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (812 aa)
PGRI_095440Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (377 aa)
PGRI_095420Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (575 aa)
PGRI_094260Heterokaryon incompatibility. (993 aa)
PGRI_094490Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (372 aa)
PGRI_089670Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase. (385 aa)
PGRI_082840Aromatic amino acid beta-eliminating lyase/threonine aldolase. (389 aa)
PGRI_083220Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (274 aa)
PGRI_083660Homocysteine S-methyltransferase. (316 aa)
PGRI_083550Uncharacterized protein. (938 aa)
PGRI_083650Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (365 aa)
PGRI_084630Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (428 aa)
PGRI_085910Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (398 aa)
PGRI_085640Amidohydrolase. (420 aa)
PGRI_085400Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (461 aa)
PGRI_085550Aldolase-type TIM barrel. (707 aa)
PGRI_086570Prephenate dehydratase. (317 aa)
PGRI_086710Homoserine kinase. (336 aa)
PGRI_086490Aspartokinase. (518 aa)
PGRI_087970Asparagine synthase, glutamine-hydrolyzing. (573 aa)
PGRI_088310Acetolactate synthase, small subunit. (362 aa)
PGRI_088290Aspartate/ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (380 aa)
PGRI_088510Cobalamin-independent methionine synthase. (768 aa)
PGRI_079030Glutamate synthase, central-N. (2121 aa)
PGRI_079210ADC synthase. (101 aa)
PGRI_080730Tryptophan synthase. (403 aa)
PGRI_081640ATP-grasp fold, subdomain 1. (2218 aa)
PGRI_081940Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha. (481 aa)
PGRI_000650ADC synthase. (1077 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (709 aa)
PGRI_001610Glutamine synthetase. (359 aa)
PGRI_002430Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
PGRI_003230Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (520 aa)
PGRI_0032803-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (588 aa)
PGRI_004080Aminotransferase, class IV. (319 aa)
PGRI_004030Aldolase-type TIM barrel; Belongs to the DapA family. (325 aa)
PGRI_004040Aspartate aminotransferase. (414 aa)
PGRI_006610NADP oxidoreductase, coenzyme F420-dependent. (292 aa)
PGRI_007930Threonine dehydratase. (568 aa)
PGRI_009240Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (303 aa)
PGRI_009340Pyridoxal phosphate-dependent transferase, major region, subdomain 2. (766 aa)
PGRI_009360Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (520 aa)
PGRI_009760Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (551 aa)
PGRI_071690Aspartate/other aminotransferase. (418 aa)
PGRI_072520Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (396 aa)
PGRI_072150Carbamoyl-phosphate synthase, large subunit. (1166 aa)
PGRI_072550Prephenate dehydrogenase. (392 aa)
PGRI_073700DAHP synthetase I/KDSA. (1176 aa)
PGRI_073890Aspartate/glutamate/uridylate kinase. (468 aa)
PGRI_074260Aconitase/3-isopropylmalate dehydratase, swivel. (607 aa)
PGRI_074600N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family. (893 aa)
PGRI_075180Aspartate aminotransferase. (416 aa)
PGRI_075090NADP oxidoreductase, coenzyme F420-dependent. (301 aa)
PGRI_076610Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (337 aa)
PGRI_077200Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (276 aa)
PGRI_0775204'-phosphopantetheinyl transferase. (392 aa)
PGRI_078580Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (521 aa)
PGRI_078610Aspartate/glutamate/uridylate kinase. (428 aa)
PGRI_078390Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (917 aa)
PGRI_078790Gamma-glutamyl phosphate reductase GPR. (457 aa)
PGRI_095820Uncharacterized protein. (423 aa)
PGRI_041660Aconitase/3-isopropylmalate dehydratase, swivel. (1195 aa)
PGRI_042230Chorismate synthase. (407 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (383 aa)
PGRI_040570Iso_dh domain-containing protein. (360 aa)
PGRI_045590Pyridoxal phosphate-dependent transferase, major region, subdomain 2. (611 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
PGRI_047380Delta crystallin. (469 aa)
PGRI_048540Uncharacterized protein. (346 aa)
PGRI_048980Homocysteine S-methyltransferase. (313 aa)
PGRI_048620Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (537 aa)
PGRI_049270Phosphoserine phosphatase, domain 2. (453 aa)
PGRI_049600Aspartate-semialdehyde dehydrogenase. (364 aa)
PGRI_049260Phosphoadenosine phosphosulfate reductase CysH. (310 aa)
PGRI_0511203-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (774 aa)
PGRI_0516903-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
PGRI_051770Methionine synthase, vitamin-B12 independent. (404 aa)
PGRI_051650Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (715 aa)
PGRI_051160Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (612 aa)
PGRI_053570Amidohydrolase. (430 aa)
PGRI_054630Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily. (367 aa)
PGRI_054620Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (397 aa)
PGRI_039280Uncharacterized protein. (210 aa)
PGRI_034720Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (787 aa)
PGRI_035110Uncharacterized protein. (226 aa)
PGRI_035620Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (211 aa)
PGRI_035810Acetolactate synthase. (663 aa)
PGRI_036520Homoserine dehydrogenase. (370 aa)
PGRI_036750Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (375 aa)
PGRI_037830Dihydroxy-acid/6-phosphogluconate dehydratase. (608 aa)
PGRI_038150Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (458 aa)
PGRI_038080Uncharacterized protein. (210 aa)
PGRI_038760Ornithine aminotransferase. (450 aa)
PGRI_011470Nitrogen regulatory PII-like, alpha/beta. (312 aa)
PGRI_011940Chorismate mutase. (267 aa)
PGRI_014350Pyridoxal phosphate-dependent transferase, major region, subdomain 2. (398 aa)
PGRI_014910Phospho-2-dehydro-3-deoxyheptonate aldolase. (364 aa)
PGRI_014850Uncharacterized protein. (638 aa)
PGRI_015300FtsJ domain-containing protein. (367 aa)
PGRI_015970D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa)
PGRI_016530Transcription factor. (430 aa)
PGRI_017240Dihydroxy-acid/6-phosphogluconate dehydratase. (585 aa)
PGRI_018030Riboflavin synthase-like beta-barrel. (641 aa)
PGRI_018580Pyridoxal phosphate-dependent decarboxylase. (1027 aa)
PGRI_018750Tryptophan synthase. (723 aa)
PGRI_018960NADP oxidoreductase, coenzyme F420-dependent. (290 aa)
PGRI_020160S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (310 aa)
PGRI_021770D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (771 aa)
PGRI_021900Argininosuccinate synthetase, catalytic/multimerization domain body. (416 aa)
PGRI_022430Pyridoxal phosphate-dependent transferase, major region, subdomain 2. (536 aa)
PGRI_023890Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (284 aa)
PGRI_024170Uncharacterized protein. (191 aa)
PGRI_025790Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
PGRI_026430Methionine synthase, vitamin-B12 independent. (402 aa)
PGRI_028070Acetolactate synthase. (693 aa)
PGRI_030040Anthranilate synthase/para-aminobenzoate synthase, glutamine amidotransferase. (751 aa)
PGRI_030760Uncharacterized protein. (436 aa)
PGRI_030590D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (347 aa)
PGRI_030980Aldolase-type TIM barrel. (638 aa)
Your Current Organism:
Penicillium griseofulvum
NCBI taxonomy Id: 5078
Other names: CBS 185.27, P. griseofulvum, Penicillium patulum
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