74 items (Penicillium griseofulvum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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	PGRI_087400	Malate dehydrogenase. (340 aa)
	PGRI_079030	Glutamate synthase, central-N. (2121 aa)
	PGRI_080300	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (542 aa)
	PGRI_080430	Bicupin, oxalate decarboxylase/oxidase. (407 aa)
	PGRI_080310	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (463 aa)
	PGRI_080650	Malic enzyme. (573 aa)
	PGRI_000330	Dehydrogenase, E1 component. (1059 aa)
	PGRI_002780	Carbon-nitrogen hydrolase. (412 aa)
	PGRI_003190	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (512 aa)
	PGRI_004040	Aspartate aminotransferase. (414 aa)
	PGRI_004580	Dehydrogenase, E1 component. (405 aa)
	PGRI_004590	Transket_pyr domain-containing protein. (403 aa)
	PGRI_005770	Uncharacterized protein. (88 aa)
	PGRI_007890	Succinate-semialdehyde dehydrogenase. (532 aa)
	PGRI_075770	Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase. (327 aa)
	PGRI_075160	Fumarate lyase. (536 aa)
	PGRI_075180	Aspartate aminotransferase. (416 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (484 aa)
	PGRI_071690	Aspartate/other aminotransferase. (418 aa)
	PGRI_078390	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (917 aa)
	PGRI_077990	Malic enzyme. (602 aa)
	PGRI_077200	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (276 aa)
	PGRI_076260	Transcription factor. (616 aa)
	PGRI_071830	Dihydropteroate synthase. (412 aa)
	PGRI_041000	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (578 aa)
	PGRI_041030	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (347 aa)
	PGRI_042230	Chorismate synthase. (407 aa)
	PGRI_042380	Ribosomal protein S36, mitochondrial. (119 aa)
	PGRI_040210	Alcohol dehydrogenase, iron-type. (357 aa)
	PGRI_040460	Monooxygenase, FAD-binding. (446 aa)
	PGRI_047770	Aminotransferase, class IV. (256 aa)
	PGRI_049940	Aldehyde/histidinol dehydrogenase. (499 aa)
	PGRI_049600	Aspartate-semialdehyde dehydrogenase. (364 aa)
	PGRI_053570	Amidohydrolase. (430 aa)
	PGRI_035730	Shikimate kinase. (889 aa)
	PGRI_035710	Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase. (351 aa)
	PGRI_038150	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (458 aa)
	PGRI_038080	Uncharacterized protein. (210 aa)
	PGRI_038760	Ornithine aminotransferase. (450 aa)
	PGRI_011940	Chorismate mutase. (267 aa)
	PGRI_015300	FtsJ domain-containing protein. (367 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (464 aa)
	PGRI_018540	Aspartate aminotransferase. (429 aa)
	PGRI_018970	Aldehyde/histidinol dehydrogenase. (534 aa)
	PGRI_018950	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (547 aa)
	PGRI_020110	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (479 aa)
	PGRI_020160	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (310 aa)
	PGRI_020130	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (574 aa)
	PGRI_021310	Complex 1 LYR protein. (128 aa)
	PGRI_025790	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
	PGRI_028570	FolB domain-containing protein. (313 aa)
	PGRI_045520	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (313 aa)
	PGRI_032780	FtsJ domain-containing protein. (374 aa)
	PGRI_056010	GTP cyclohydrolase I/Nitrile oxidoreductase. (342 aa)
	PGRI_056280	3-hydroxyanthranilic acid dioxygenase. (238 aa)
	PGRI_057190	Aldehyde/histidinol dehydrogenase; Belongs to the aldehyde dehydrogenase family. (860 aa)
	PGRI_057490	Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (498 aa)
	PGRI_061490	Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (339 aa)
	PGRI_061500	Succinate-semialdehyde dehydrogenase. (493 aa)
	PGRI_070230	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
	PGRI_044830	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1578 aa)
	PGRI_065810	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1091 aa)
	PGRI_067220	Malate dehydrogenase, type 1; Belongs to the LDH/MDH superfamily. (330 aa)
	PGRI_067930	Glutamine amidotransferase type 1. (804 aa)
	PGRI_095300	Pyridoxal phosphate-dependent transferase, major region, subdomain 2. (346 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (192 aa)
	PGRI_090790	Shikimate kinase. (832 aa)
	PGRI_090940	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (492 aa)
	PGRI_083480	Bicupin, oxalate decarboxylase/oxidase. (797 aa)
	PGRI_085640	Amidohydrolase. (420 aa)
	PGRI_085400	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (461 aa)
	PGRI_085550	Aldolase-type TIM barrel. (707 aa)
	PGRI_086350	Wings apart-like protein. (816 aa)
	PGRI_087770	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (413 aa)

Your Current Organism:

Penicillium griseofulvum

NCBI taxonomy Id: 5078
Other names: CBS 185.27, P. griseofulvum, Penicillium patulum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA1	BNA5	A0A135LR09	A0A135LG22	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.972
BNA1	BNA5-2	A0A135LR09	A0A135LYQ4	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.973
BNA1	PGRI_040460	A0A135LR09	A0A135L953	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Monooxygenase, FAD-binding.	0.838
BNA1	PGRI_045520	A0A135LR09	A0A135LKB6	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.528
BNA1	PGRI_056280	A0A135LR09	A0A135LL78	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	3-hydroxyanthranilic acid dioxygenase.	0.892
BNA5	BNA1	A0A135LG22	A0A135LR09	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.972
BNA5	BNA5-2	A0A135LG22	A0A135LYQ4	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.887
BNA5	PGRI_040460	A0A135LG22	A0A135L953	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Monooxygenase, FAD-binding.	0.983
BNA5	PGRI_045520	A0A135LG22	A0A135LKB6	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.484
BNA5	PGRI_056280	A0A135LG22	A0A135LL78	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	3-hydroxyanthranilic acid dioxygenase.	0.957
BNA5-2	BNA1	A0A135LYQ4	A0A135LR09	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.973
BNA5-2	BNA5	A0A135LYQ4	A0A135LG22	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.887
BNA5-2	PGRI_040460	A0A135LYQ4	A0A135L953	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Monooxygenase, FAD-binding.	0.979
BNA5-2	PGRI_045520	A0A135LYQ4	A0A135LKB6	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.484
BNA5-2	PGRI_056280	A0A135LYQ4	A0A135LL78	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	3-hydroxyanthranilic acid dioxygenase.	0.957
PGRI_000330	PGRI_004040	A0A135LVI6	A0A135LWL2	Dehydrogenase, E1 component.	Aspartate aminotransferase.	0.892
PGRI_000330	PGRI_007890	A0A135LVI6	A0A135LXP7	Dehydrogenase, E1 component.	Succinate-semialdehyde dehydrogenase.	0.894
PGRI_000330	PGRI_018540	A0A135LVI6	A0A135LGA4	Dehydrogenase, E1 component.	Aspartate aminotransferase.	0.907
PGRI_000330	PGRI_018970	A0A135LVI6	A0A135LGB5	Dehydrogenase, E1 component.	Aldehyde/histidinol dehydrogenase.	0.495
PGRI_000330	PGRI_020130	A0A135LVI6	A0A135LGS8	Dehydrogenase, E1 component.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.495