(57 nodes) Mismatch repair network (Penicillium griseofulvum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGRI_011450	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1128 aa)
	PGRI_011350	Uncharacterized protein. (395 aa)
	PGRI_037810	Uncharacterized protein. (146 aa)
	PGRI_037470	Uncharacterized protein. (638 aa)
	PGRI_036350	DNA mismatch repair protein MutS, core. (879 aa)
	PGRI_035450	Uncharacterized protein. (277 aa)
	PGRI_053340	Uncharacterized protein. (192 aa)
	PGRI_050160	Uncharacterized protein. (229 aa)
	PGRI_050280	Uncharacterized protein. (120 aa)
	PGRI_048570	XPG/RAD2 endonuclease. (669 aa)
	PGRI_046590	ATPase, AAA-type, core. (393 aa)
	PGRI_034110	RT_RNaseH domain-containing protein. (253 aa)
	PGRI_033650	Uncharacterized protein. (529 aa)
	PGRI_039710	DNA helicase, DEXX box type. (986 aa)
	PGRI_039730	Acetamidase/Formamidase. (317 aa)
	PGRI_005810	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
	PGRI_007770	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1222 aa)
	PGRI_008190	DNA polymerase alpha/epsilon, subunit B. (544 aa)
	PGRI_009700	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	PGRI_073780	DNA mismatch repair protein MutS, core. (855 aa)
	PGRI_012180	Uncharacterized protein. (453 aa)
	PGRI_073960	Reverse transcriptase, RNA-dependent DNA polymerase. (148 aa)
	PGRI_075190	Integrase, catalytic core. (309 aa)
	PGRI_077100	DNA ligase. (873 aa)
	PGRI_080490	Chromo domain/shadow. (267 aa)
	PGRI_080690	DNA polymerase delta, subunit 4. (181 aa)
	PGRI_080570	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (246 aa)
	PGRI_081430	Nucleic acid-binding, OB-fold. (273 aa)
	PGRI_001560	Tetratricopeptide-like helical. (490 aa)
	PGRI_004930	Uncharacterized protein. (836 aa)
	PGRI_005800	Vezatin domain-containing protein. (611 aa)
	PGRI_013140	Ribosomal protein S5 domain 2-type fold, subgroup. (761 aa)
	PGRI_018800	Nucleic acid-binding, OB-fold. (280 aa)
	PGRI_020740	Zds_C domain-containing protein. (837 aa)
	PGRI_021280	Uncharacterized protein. (500 aa)
	PGRI_022280	Ribosomal protein S5 domain 2-type fold, subgroup. (1007 aa)
	PGRI_025490	DNA mismatch repair protein, MSH2; Component of the post-replicative DNA mismatch repair system (MMR). (942 aa)
	PGRI_026970	Uncharacterized protein. (507 aa)
	PGRI_027320	DNA ligase. (813 aa)
	PGRI_058960	Uncharacterized protein. (829 aa)
	PGRI_059460	Primosome PriB/single-strand DNA-binding. (145 aa)
	PGRI_070070	Uncharacterized protein. (102 aa)
	PGRI_070490	ATPase, AAA-type, core. (1894 aa)
	PGRI_070520	AAA domain-containing protein. (352 aa)
	PGRI_066040	Exonuclease, RNase T/DNA polymerase III. (291 aa)
	PGRI_067470	ATPase, AAA-type, core. (350 aa)
	PGRI_093520	DNA mismatch repair protein MutS, core. (904 aa)
	PGRI_094100	CWC16 protein. (307 aa)
	PGRI_094880	ATPase, AAA-type, core. (876 aa)
	PGRI_094510	Uncharacterized protein. (389 aa)
	PGRI_090210	Reverse transcriptase. (103 aa)
	PGRI_083860	Ribosomal protein S5 domain 2-type fold, subgroup. (878 aa)
	PGRI_085440	MutL, C-terminal, dimerization. (807 aa)
	PGRI_088270	Nuclear envelope, Cut8; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins. (311 aa)
	PGRI_079410	DNA polymerase. (1104 aa)
	PGRI_080400	ATPase, AAA-type, core. (1176 aa)
	PGRI_011620	Replication factor A protein 3. (118 aa)

Your Current Organism:

Penicillium griseofulvum

NCBI taxonomy Id: 5078
Other names: CBS 185.27, P. griseofulvum, Penicillium patulum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGRI_001560	PGRI_009700	A0A135LVX2	A0A135LY88	Tetratricopeptide-like helical.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.680
PGRI_001560	PGRI_018800	A0A135LVX2	A0A135LGI2	Tetratricopeptide-like helical.	Nucleic acid-binding, OB-fold.	0.602
PGRI_001560	PGRI_081430	A0A135LVX2	A0A135LV85	Tetratricopeptide-like helical.	Nucleic acid-binding, OB-fold.	0.670
PGRI_004930	PGRI_009700	A0A135LWU9	A0A135LY88	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.680
PGRI_004930	PGRI_018800	A0A135LWU9	A0A135LGI2	Uncharacterized protein.	Nucleic acid-binding, OB-fold.	0.602
PGRI_004930	PGRI_081430	A0A135LWU9	A0A135LV85	Uncharacterized protein.	Nucleic acid-binding, OB-fold.	0.670
PGRI_005800	PGRI_005810	A0A135LX40	A0A135LX93	Vezatin domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.899
PGRI_005800	PGRI_007770	A0A135LX40	A0A135LXM6	Vezatin domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.982
PGRI_005800	PGRI_008190	A0A135LX40	A0A135LXR8	Vezatin domain-containing protein.	DNA polymerase alpha/epsilon, subunit B.	0.974
PGRI_005800	PGRI_009700	A0A135LX40	A0A135LY88	Vezatin domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.951
PGRI_005800	PGRI_011450	A0A135LX40	A0A135LE87	Vezatin domain-containing protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.938
PGRI_005800	PGRI_013140	A0A135LX40	A0A135LEP1	Vezatin domain-containing protein.	Ribosomal protein S5 domain 2-type fold, subgroup.	0.863
PGRI_005800	PGRI_018800	A0A135LX40	A0A135LGI2	Vezatin domain-containing protein.	Nucleic acid-binding, OB-fold.	0.863
PGRI_005800	PGRI_022280	A0A135LX40	A0A135LHD6	Vezatin domain-containing protein.	Ribosomal protein S5 domain 2-type fold, subgroup.	0.847
PGRI_005800	PGRI_025490	A0A135LX40	A0A135LIA8	Vezatin domain-containing protein.	DNA mismatch repair protein, MSH2; Component of the post-replicative DNA mismatch repair system (MMR).	0.961
PGRI_005800	PGRI_027320	A0A135LX40	A0A135LIR3	Vezatin domain-containing protein.	DNA ligase.	0.960
PGRI_005800	PGRI_036350	A0A135LX40	A0A135LD45	Vezatin domain-containing protein.	DNA mismatch repair protein MutS, core.	0.829
PGRI_005800	PGRI_039710	A0A135LX40	A0A135L8Y9	Vezatin domain-containing protein.	DNA helicase, DEXX box type.	0.932
PGRI_005800	PGRI_039730	A0A135LX40	A0A135L8Y6	Vezatin domain-containing protein.	Acetamidase/Formamidase.	0.779
PGRI_005800	PGRI_046590	A0A135LX40	A0A135LA32	Vezatin domain-containing protein.	ATPase, AAA-type, core.	0.993