STRINGSTRING
Cseg_0072 Cseg_0072 Cseg_0226 Cseg_0226 ispH ispH Cseg_0389 Cseg_0389 Cseg_0392 Cseg_0392 Cseg_0849 Cseg_0849 ispG ispG Cseg_1307 Cseg_1307 Cseg_1361 Cseg_1361 dxs dxs ispE ispE Cseg_1914 Cseg_1914 ispDF ispDF dxr dxr Cseg_2206 Cseg_2206 Cseg_2255 Cseg_2255 Cseg_2368 Cseg_2368 Cseg_2529 Cseg_2529 Cseg_3393 Cseg_3393 Cseg_3584 Cseg_3584
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cseg_0072acetyl-CoA acetyltransferase; KEGG: ccs:CCNA_00075 3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
Cseg_0226KEGG: cak:Caul_4752 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (319 aa)
Cseg_0389KEGG: cak:Caul_4519 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
Cseg_0392KEGG: ccs:CCNA_00544 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Cseg_0849KEGG: ccs:CCNA_03209 acetyl-coenzyme A synthetase; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (379 aa)
Cseg_1307Trans-hexaprenyltranstransferase; KEGG: ccr:CC_2113 polyprenyl synthetase family protein; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (341 aa)
Cseg_1361PFAM: Polyprenyl synthetase; KEGG: ccs:CCNA_02150 dimethylallyltransferase/geranyltranstransferase; Belongs to the FPP/GGPP synthase family. (299 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (640 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (290 aa)
Cseg_1914Propanoyl-CoA C-acyltransferase; KEGG: ccs:CCNA_01499 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
ispDF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (382 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (398 aa)
Cseg_2206Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa)
Cseg_2255KEGG: ccs:CCNA_02045 acetyl-coenzyme A synthetase. (512 aa)
Cseg_2368KEGG: cak:Caul_4010 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
Cseg_2529KEGG: cak:Caul_4010 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
Cseg_3393KEGG: ccs:CCNA_00938 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Cseg_3584acetyl-CoA acetyltransferase; KEGG: ccs:CCNA_00820 3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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