STRINGSTRING
ETZ24743.1 ETZ24743.1 ETZ20577.1 ETZ20577.1 mdh mdh sucD sucD ETZ19689.1 ETZ19689.1 sdhA sdhA ETZ19691.1 ETZ19691.1 fumC fumC ETZ19370.1 ETZ19370.1 pckA pckA ETZ23273.1 ETZ23273.1 ETZ23289.1 ETZ23289.1 sdhA-2 sdhA-2 ETZ23291.1 ETZ23291.1 sucC sucC gltA gltA mqo mqo ETZ22225.1 ETZ22225.1 ETZ22226.1 ETZ22226.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ETZ24743.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (897 aa)
ETZ20577.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (203 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
sucDsuccinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
ETZ19689.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (256 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (659 aa)
ETZ19691.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (226 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
ETZ19370.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (862 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
ETZ23273.1Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (332 aa)
ETZ23289.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (227 aa)
sdhA-2Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (638 aa)
ETZ23291.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa)
sucCmalate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the citrate synthase family. (429 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (499 aa)
ETZ22225.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (148 aa)
ETZ22226.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (312 aa)
Your Current Organism:
Pedobacter sp. V48
NCBI taxonomy Id: 509635
Other names: P. sp. V48
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