STRINGSTRING
ETZ24686.1 ETZ24686.1 ETZ20912.1 ETZ20912.1 mdh mdh ETZ19919.1 ETZ19919.1 ETZ19920.1 ETZ19920.1 sucD sucD ETZ19689.1 ETZ19689.1 sdhA sdhA ETZ19691.1 ETZ19691.1 ETZ19733.1 ETZ19733.1 ETZ19734.1 ETZ19734.1 ETZ19735.1 ETZ19735.1 fumC fumC ETZ19467.1 ETZ19467.1 pckA pckA ETZ23289.1 ETZ23289.1 sdhA-2 sdhA-2 ETZ23291.1 ETZ23291.1 sucC sucC ETZ23553.1 ETZ23553.1 ETZ22891.1 ETZ22891.1 gltA gltA ETZ22138.1 ETZ22138.1 mqo mqo ETZ21259.1 ETZ21259.1 ETZ21260.1 ETZ21260.1 ETZ21264.1 ETZ21264.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ETZ24686.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (125 aa)
ETZ20912.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (460 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
ETZ19919.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (410 aa)
ETZ19920.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (356 aa)
sucDsuccinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
ETZ19689.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (256 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (659 aa)
ETZ19691.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (226 aa)
ETZ19733.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (549 aa)
ETZ19734.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (207 aa)
ETZ19735.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (132 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
ETZ19467.1Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
ETZ23289.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (227 aa)
sdhA-2Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (638 aa)
ETZ23291.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa)
sucCmalate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
ETZ23553.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (462 aa)
ETZ22891.1Diapophytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (443 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the citrate synthase family. (429 aa)
ETZ22138.1Import component protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (110 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (499 aa)
ETZ21259.12-oxoglutarate dehydrogenase E1; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (931 aa)
ETZ21260.12-oxoglutarate dehydrogenase E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (409 aa)
ETZ21264.1Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (468 aa)
Your Current Organism:
Pedobacter sp. V48
NCBI taxonomy Id: 509635
Other names: P. sp. V48
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