(14 nodes) HDACs deacetylate histones, and Histone deacetylase network (Necator americanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_14453	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (500 aa)
	NECAME_01050	HMG box. (348 aa)
	NECAME_00813	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (464 aa)
	NECAME_13442	CHDCT2 domain protein. (2054 aa)
	NECAME_11463	BAH domain protein. (403 aa)
	NECAME_11462	MTA_R1 domain-containing protein. (168 aa)
	NECAME_00326	Myb-like DNA-binding domain protein. (547 aa)
	NECAME_09291	Uncharacterized protein. (150 aa)
	NECAME_09289	P66_CC domain-containing protein. (352 aa)
	NECAME_09290	Uncharacterized protein. (167 aa)
	NECAME_00254	Amino_oxidase domain-containing protein. (189 aa)
	NECAME_00255	SWIRM domain protein. (315 aa)
	NECAME_00253	Amino_oxidase domain-containing protein. (145 aa)
	NECAME_06271	Uncharacterized protein. (212 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00253	NECAME_00254	W2TLK2	W2TJC8	Amino_oxidase domain-containing protein.	Amino_oxidase domain-containing protein.	0.821
NECAME_00253	NECAME_00255	W2TLK2	W2TJV0	Amino_oxidase domain-containing protein.	SWIRM domain protein.	0.893
NECAME_00253	NECAME_00326	W2TLK2	W2TAS1	Amino_oxidase domain-containing protein.	Myb-like DNA-binding domain protein.	0.736
NECAME_00253	NECAME_00813	W2TLK2	W2SVE7	Amino_oxidase domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.665
NECAME_00253	NECAME_01050	W2TLK2	W2SN17	Amino_oxidase domain-containing protein.	HMG box.	0.841
NECAME_00253	NECAME_06271	W2TLK2	W2TXL7	Amino_oxidase domain-containing protein.	Uncharacterized protein.	0.559
NECAME_00253	NECAME_11462	W2TLK2	W2T720	Amino_oxidase domain-containing protein.	MTA_R1 domain-containing protein.	0.502
NECAME_00253	NECAME_11463	W2TLK2	W2T4H7	Amino_oxidase domain-containing protein.	BAH domain protein.	0.502
NECAME_00253	NECAME_13442	W2TLK2	W2SVX7	Amino_oxidase domain-containing protein.	CHDCT2 domain protein.	0.752
NECAME_00253	NECAME_14453	W2TLK2	W2SMH3	Amino_oxidase domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.665
NECAME_00254	NECAME_00253	W2TJC8	W2TLK2	Amino_oxidase domain-containing protein.	Amino_oxidase domain-containing protein.	0.821
NECAME_00254	NECAME_00255	W2TJC8	W2TJV0	Amino_oxidase domain-containing protein.	SWIRM domain protein.	0.902
NECAME_00254	NECAME_00326	W2TJC8	W2TAS1	Amino_oxidase domain-containing protein.	Myb-like DNA-binding domain protein.	0.736
NECAME_00254	NECAME_00813	W2TJC8	W2SVE7	Amino_oxidase domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.665
NECAME_00254	NECAME_01050	W2TJC8	W2SN17	Amino_oxidase domain-containing protein.	HMG box.	0.841
NECAME_00254	NECAME_06271	W2TJC8	W2TXL7	Amino_oxidase domain-containing protein.	Uncharacterized protein.	0.559
NECAME_00254	NECAME_11462	W2TJC8	W2T720	Amino_oxidase domain-containing protein.	MTA_R1 domain-containing protein.	0.502
NECAME_00254	NECAME_11463	W2TJC8	W2T4H7	Amino_oxidase domain-containing protein.	BAH domain protein.	0.502
NECAME_00254	NECAME_13442	W2TJC8	W2SVX7	Amino_oxidase domain-containing protein.	CHDCT2 domain protein.	0.752
NECAME_00254	NECAME_14453	W2TJC8	W2SMH3	Amino_oxidase domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.665