(37 nodes) TOR complex, and TSC1-TSC2 complex network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_14955	Uncharacterized protein. (131 aa)
	NECAME_14956	Uncharacterized protein. (174 aa)
	NECAME_04827	Protein kinase domain-containing protein. (522 aa)
	NECAME_04687	Uncharacterized protein. (122 aa)
	NECAME_04686	Uncharacterized protein. (491 aa)
	NECAME_19284	FAT domain-containing protein. (159 aa)
	NECAME_18926	Uncharacterized protein. (169 aa)
	NECAME_18954	Uncharacterized protein. (160 aa)
	NECAME_18455	Uncharacterized protein. (141 aa)
	NECAME_18440	Serine/threonine-protein kinase TOR. (221 aa)
	NECAME_18872	Uncharacterized protein. (163 aa)
	NECAME_13418	Uncharacterized protein. (83 aa)
	NECAME_03863	Ras family protein. (172 aa)
	NECAME_00664	Protein kinase domain-containing protein. (580 aa)
	NECAME_12313	WD domain, G-beta repeat protein. (256 aa)
	NECAME_03442	Uncharacterized protein. (227 aa)
	NECAME_11530	Uncharacterized protein. (303 aa)
	NECAME_03441	Uncharacterized protein. (392 aa)
	NECAME_11475	Uncharacterized protein. (213 aa)
	NECAME_11627	Kinase domain protein; Belongs to the protein kinase superfamily. (484 aa)
	NECAME_03444	Uncharacterized protein. (188 aa)
	NECAME_11472	Raptor_N domain-containing protein. (305 aa)
	NECAME_11473	Uncharacterized protein. (250 aa)
	NECAME_10602	DUF3384 domain-containing protein. (568 aa)
	NECAME_10603	Rap/ran-GAP. (849 aa)
	NECAME_09910	Uncharacterized protein. (99 aa)
	NECAME_09911	Uncharacterized protein. (108 aa)
	NECAME_17710	Rapamycin binding domain protein. (352 aa)
	NECAME_17708	Uncharacterized protein. (400 aa)
	NECAME_17709	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family. (110 aa)
	NECAME_17711	Uncharacterized protein. (226 aa)
	NECAME_06644	RICTOR_V domain-containing protein. (517 aa)
	NECAME_06642	RICTOR_N domain-containing protein. (690 aa)
	NECAME_06436	Non-specific serine/threonine protein kinase. (677 aa)
	NECAME_00087	Kinase domain protein; Belongs to the protein kinase superfamily. (343 aa)
	NECAME_00088	Kinase domain protein; Belongs to the protein kinase superfamily. (429 aa)
	NECAME_00085	Uncharacterized protein. (90 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00085	NECAME_03441	W2U1H6	W2T4K5	Uncharacterized protein.	Uncharacterized protein.	0.468
NECAME_00085	NECAME_03442	W2U1H6	W2T3C5	Uncharacterized protein.	Uncharacterized protein.	0.468
NECAME_00085	NECAME_03444	W2U1H6	W2T6A5	Uncharacterized protein.	Uncharacterized protein.	0.468
NECAME_00085	NECAME_03863	W2U1H6	W2SZA6	Uncharacterized protein.	Ras family protein.	0.590
NECAME_00085	NECAME_04827	W2U1H6	W2SLW8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.725
NECAME_00085	NECAME_06436	W2U1H6	W2TU86	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.687
NECAME_00085	NECAME_06642	W2U1H6	W2TSW0	Uncharacterized protein.	RICTOR_N domain-containing protein.	0.890
NECAME_00085	NECAME_06644	W2U1H6	W2TS13	Uncharacterized protein.	RICTOR_V domain-containing protein.	0.890
NECAME_00085	NECAME_10602	W2U1H6	W2T7V2	Uncharacterized protein.	DUF3384 domain-containing protein.	0.542
NECAME_00085	NECAME_10603	W2U1H6	W2TA64	Uncharacterized protein.	Rap/ran-GAP.	0.542
NECAME_00085	NECAME_11472	W2U1H6	W2T6I9	Uncharacterized protein.	Raptor_N domain-containing protein.	0.555
NECAME_00085	NECAME_11473	W2U1H6	W2T704	Uncharacterized protein.	Uncharacterized protein.	0.555
NECAME_00085	NECAME_11475	W2U1H6	W2T5A7	Uncharacterized protein.	Uncharacterized protein.	0.555
NECAME_00085	NECAME_11627	W2U1H6	W2T5J1	Uncharacterized protein.	Kinase domain protein; Belongs to the protein kinase superfamily.	0.725
NECAME_00085	NECAME_12313	W2U1H6	W2T2P2	Uncharacterized protein.	WD domain, G-beta repeat protein.	0.653
NECAME_00085	NECAME_14955	W2U1H6	W2SKE6	Uncharacterized protein.	Uncharacterized protein.	0.607
NECAME_00085	NECAME_14956	W2U1H6	W2SKK3	Uncharacterized protein.	Uncharacterized protein.	0.796
NECAME_00085	NECAME_17708	W2U1H6	W2TKY4	Uncharacterized protein.	Uncharacterized protein.	0.549
NECAME_00085	NECAME_17709	W2U1H6	W2TLE6	Uncharacterized protein.	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	0.549
NECAME_00085	NECAME_17710	W2U1H6	W2TK51	Uncharacterized protein.	Rapamycin binding domain protein.	0.549