(7 nodes) C-terminal protein lipidation, and Xenophagy network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_13711	Gamma-aminobutyric acid receptor-associated protein. (118 aa)
	NECAME_12622	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (96 aa)
	NECAME_12737	Autophagy-related protein 3. (310 aa)
	NECAME_03712	WD domain, G-beta repeat protein. (461 aa)
	NECAME_11138	WD domain, G-beta repeat protein. (295 aa)
	NECAME_10568	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (786 aa)
	NECAME_00223	Autophagy protein 5; Involved in autophagic vesicle formation. (513 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00223	NECAME_03712	W2TJA7	W2T3G4	Autophagy protein 5; Involved in autophagic vesicle formation.	WD domain, G-beta repeat protein.	0.999
NECAME_00223	NECAME_10568	W2TJA7	W2T929	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.909
NECAME_00223	NECAME_11138	W2TJA7	W2T6V2	Autophagy protein 5; Involved in autophagic vesicle formation.	WD domain, G-beta repeat protein.	0.965
NECAME_00223	NECAME_12622	W2TJA7	W2SZ01	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
NECAME_00223	NECAME_12737	W2TJA7	W2T0K1	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 3.	0.998
NECAME_00223	NECAME_13711	W2TJA7	W2STQ2	Autophagy protein 5; Involved in autophagic vesicle formation.	Gamma-aminobutyric acid receptor-associated protein.	0.932
NECAME_03712	NECAME_00223	W2T3G4	W2TJA7	WD domain, G-beta repeat protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
NECAME_03712	NECAME_10568	W2T3G4	W2T929	WD domain, G-beta repeat protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.886
NECAME_03712	NECAME_11138	W2T3G4	W2T6V2	WD domain, G-beta repeat protein.	WD domain, G-beta repeat protein.	0.998
NECAME_03712	NECAME_12622	W2T3G4	W2SZ01	WD domain, G-beta repeat protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
NECAME_03712	NECAME_12737	W2T3G4	W2T0K1	WD domain, G-beta repeat protein.	Autophagy-related protein 3.	0.998
NECAME_03712	NECAME_13711	W2T3G4	W2STQ2	WD domain, G-beta repeat protein.	Gamma-aminobutyric acid receptor-associated protein.	0.879
NECAME_10568	NECAME_00223	W2T929	W2TJA7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.909
NECAME_10568	NECAME_03712	W2T929	W2T3G4	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	WD domain, G-beta repeat protein.	0.886
NECAME_10568	NECAME_11138	W2T929	W2T6V2	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	WD domain, G-beta repeat protein.	0.910
NECAME_10568	NECAME_12622	W2T929	W2SZ01	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
NECAME_10568	NECAME_12737	W2T929	W2T0K1	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	Autophagy-related protein 3.	0.997
NECAME_10568	NECAME_13711	W2T929	W2STQ2	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	Gamma-aminobutyric acid receptor-associated protein.	0.999
NECAME_11138	NECAME_00223	W2T6V2	W2TJA7	WD domain, G-beta repeat protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.965
NECAME_11138	NECAME_03712	W2T6V2	W2T3G4	WD domain, G-beta repeat protein.	WD domain, G-beta repeat protein.	0.998