(42 nodes) Mixed, incl. RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known, and PcG protein complex network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_15919	Uncharacterized protein. (137 aa)
	NECAME_15922	SAM domain-containing protein. (258 aa)
	NECAME_15920	Uncharacterized protein. (55 aa)
	NECAME_01180	BRD4_CDT domain-containing protein. (552 aa)
	NECAME_15921	Uncharacterized protein. (366 aa)
	NECAME_01181	Bromodomain protein. (752 aa)
	NECAME_05289	Trypsin. (218 aa)
	NECAME_14448	HTH_48 domain-containing protein. (79 aa)
	NECAME_14772	Protein kinase domain-containing protein. (181 aa)
	NECAME_18317	Protein kinase domain-containing protein. (147 aa)
	NECAME_13079	Uncharacterized protein. (213 aa)
	NECAME_13098	JmjC domain protein. (343 aa)
	NECAME_12928	HYLS1_C domain-containing protein. (313 aa)
	NECAME_12566	Mbt repeat protein. (441 aa)
	NECAME_12380	JmjC domain protein. (519 aa)
	NECAME_03457	Uncharacterized protein. (239 aa)
	NECAME_11560	Protein, SNF2 family. (1520 aa)
	NECAME_03456	Uncharacterized protein. (245 aa)
	NECAME_11368	Zn-finger in Ran binding protein. (85 aa)
	NECAME_11584	Mbt repeat protein. (697 aa)
	NECAME_00459	Peptidase S1 domain-containing protein. (158 aa)
	NECAME_03458	Uncharacterized protein. (433 aa)
	NECAME_11166	Zinc finger, C3HC4 type. (696 aa)
	NECAME_11167	Uncharacterized protein. (266 aa)
	NECAME_10429	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (256 aa)
	NECAME_09830	Uncharacterized protein. (359 aa)
	NECAME_01910	Alpha-2-macroglobulin family protein. (271 aa)
	NECAME_01908	A2M_N_2 domain-containing protein. (208 aa)
	NECAME_01824	Kinase domain protein. (704 aa)
	NECAME_07858	Uncharacterized protein. (699 aa)
	NECAME_07810	Alpha-2-macroglobulin family protein. (776 aa)
	NECAME_07811	A-macroglobulin complement component. (996 aa)
	NECAME_08034	Cyclin protein; Belongs to the cyclin family. (540 aa)
	NECAME_01906	Uncharacterized protein. (545 aa)
	NECAME_01907	Uncharacterized protein. (256 aa)
	NECAME_06896	Zinc finger, C2H2 type. (232 aa)
	NECAME_01579	Zinc finger, C3HC4 type. (589 aa)
	NECAME_17045	Zinc finger, C3HC4 type. (392 aa)
	NECAME_06263	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (227 aa)
	NECAME_05939	Ankyrin repeat protein. (184 aa)
	NECAME_06275	CXC domain-containing protein. (427 aa)
	NECAME_05938	Chromo' (CHRromatin Organization MOdifier) domain protein. (280 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_01180	NECAME_01181	W2SHI5	W2SJK5	BRD4_CDT domain-containing protein.	Bromodomain protein.	0.629
NECAME_01180	NECAME_06263	W2SHI5	W2TUJ3	BRD4_CDT domain-containing protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.424
NECAME_01180	NECAME_10429	W2SHI5	W2T9S1	BRD4_CDT domain-containing protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.424
NECAME_01180	NECAME_12380	W2SHI5	W2T1K8	BRD4_CDT domain-containing protein.	JmjC domain protein.	0.488
NECAME_01180	NECAME_13079	W2SHI5	W2SXF2	BRD4_CDT domain-containing protein.	Uncharacterized protein.	0.504
NECAME_01180	NECAME_13098	W2SHI5	W2SXK6	BRD4_CDT domain-containing protein.	JmjC domain protein.	0.488
NECAME_01180	NECAME_14772	W2SHI5	W2SNJ7	BRD4_CDT domain-containing protein.	Protein kinase domain-containing protein.	0.422
NECAME_01180	NECAME_18317	W2SHI5	W2SUP5	BRD4_CDT domain-containing protein.	Protein kinase domain-containing protein.	0.422
NECAME_01181	NECAME_01180	W2SJK5	W2SHI5	Bromodomain protein.	BRD4_CDT domain-containing protein.	0.629
NECAME_01181	NECAME_06263	W2SJK5	W2TUJ3	Bromodomain protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.424
NECAME_01181	NECAME_10429	W2SJK5	W2T9S1	Bromodomain protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.424
NECAME_01181	NECAME_12380	W2SJK5	W2T1K8	Bromodomain protein.	JmjC domain protein.	0.488
NECAME_01181	NECAME_13079	W2SJK5	W2SXF2	Bromodomain protein.	Uncharacterized protein.	0.504
NECAME_01181	NECAME_13098	W2SJK5	W2SXK6	Bromodomain protein.	JmjC domain protein.	0.488
NECAME_01181	NECAME_14772	W2SJK5	W2SNJ7	Bromodomain protein.	Protein kinase domain-containing protein.	0.422
NECAME_01181	NECAME_18317	W2SJK5	W2SUP5	Bromodomain protein.	Protein kinase domain-containing protein.	0.422
NECAME_01579	NECAME_01906	W2TRR7	W2TNB2	Zinc finger, C3HC4 type.	Uncharacterized protein.	0.529
NECAME_01579	NECAME_01907	W2TRR7	W2TNN2	Zinc finger, C3HC4 type.	Uncharacterized protein.	0.529
NECAME_01579	NECAME_01908	W2TRR7	W2TLG8	Zinc finger, C3HC4 type.	A2M_N_2 domain-containing protein.	0.529
NECAME_01579	NECAME_01910	W2TRR7	W2TKK0	Zinc finger, C3HC4 type.	Alpha-2-macroglobulin family protein.	0.529