(10 nodes) Mixed, incl. Octopamine or tyramine signaling pathway, and Phospholipase C-activating G protein-coupled receptor signaling pathway network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_01070	Zinc finger, C4 type. (327 aa)
	NECAME_00872	Ligand-binding domain of nuclear hormone receptor. (431 aa)
	NECAME_13509	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (415 aa)
	NECAME_12033	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (575 aa)
	NECAME_09922	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family. (487 aa)
	NECAME_02375	Zinc finger, C4 type. (546 aa)
	NECAME_07588	7 transmembrane receptor. (311 aa)
	NECAME_01766	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	NECAME_07320	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	NECAME_00032	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family. (429 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00032	NECAME_01766	W2TZ93	W2TP43	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	0.503
NECAME_00872	NECAME_12033	W2SNR6	W2T2Z1	Ligand-binding domain of nuclear hormone receptor.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.440
NECAME_01070	NECAME_07588	W2SN34	W2TMW7	Zinc finger, C4 type.	7 transmembrane receptor.	0.432
NECAME_01070	NECAME_12033	W2SN34	W2T2Z1	Zinc finger, C4 type.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.425
NECAME_01766	NECAME_00032	W2TP43	W2TZ93	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	0.503
NECAME_01766	NECAME_12033	W2TP43	W2T2Z1	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.423
NECAME_02375	NECAME_09922	W2THX1	W2TC78	Zinc finger, C4 type.	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	0.417
NECAME_02375	NECAME_12033	W2THX1	W2T2Z1	Zinc finger, C4 type.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.508
NECAME_02375	NECAME_13509	W2THX1	W2SXB5	Zinc finger, C4 type.	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.499
NECAME_07588	NECAME_01070	W2TMW7	W2SN34	7 transmembrane receptor.	Zinc finger, C4 type.	0.432
NECAME_09922	NECAME_02375	W2TC78	W2THX1	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	Zinc finger, C4 type.	0.417
NECAME_09922	NECAME_13509	W2TC78	W2SXB5	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.441
NECAME_12033	NECAME_00872	W2T2Z1	W2SNR6	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Ligand-binding domain of nuclear hormone receptor.	0.440
NECAME_12033	NECAME_01070	W2T2Z1	W2SN34	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Zinc finger, C4 type.	0.425
NECAME_12033	NECAME_01766	W2T2Z1	W2TP43	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	0.423
NECAME_12033	NECAME_02375	W2T2Z1	W2THX1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Zinc finger, C4 type.	0.508
NECAME_12033	NECAME_13509	W2T2Z1	W2SXB5	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.518
NECAME_13509	NECAME_02375	W2SXB5	W2THX1	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Zinc finger, C4 type.	0.499
NECAME_13509	NECAME_09922	W2SXB5	W2TC78	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.	0.441
NECAME_13509	NECAME_12033	W2SXB5	W2T2Z1	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.518