(20 nodes) Programmed cell death involved in cell development network (Necator americanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	NECAME_02546	Ribosomal protein L32. (668 aa)
	NECAME_06456	Mov34/MPN/PAD-1 family protein. (313 aa)
	NECAME_01685	26S proteasome non-ATPase regulatory subunit 7 family protein. (360 aa)
	NECAME_07456	Ubiquitin-activating enzyme E1; Belongs to the ubiquitin-activating E1 family. (1065 aa)
	NECAME_00268	FZ domain-containing protein. (103 aa)
	NECAME_00267	Frizzled domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (231 aa)
	NECAME_02136	Uncharacterized protein. (367 aa)
	NECAME_00266	Frizzled/Smoothened family membrane region; Belongs to the G-protein coupled receptor Fz/Smo family. (283 aa)
	NECAME_02135	Uncharacterized protein. (160 aa)
	NECAME_18220	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (63 aa)
	NECAME_12182	Uncharacterized protein. (259 aa)
	NECAME_12243	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (228 aa)
	NECAME_12184	Uncharacterized protein. (208 aa)
	NECAME_12183	Protein kinase domain-containing protein. (142 aa)
	NECAME_00785	HSF-type DNA-binding domain protein. (256 aa)
	NECAME_14015	Cullin family protein; Belongs to the cullin family. (1063 aa)
	NECAME_18705	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (90 aa)
	NECAME_13931	Zinc finger, C2H2 type. (105 aa)
	NECAME_05434	Uncharacterized protein. (198 aa)
	NECAME_15775	DIX domain protein. (638 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00266	NECAME_00267	W2TIJ5	W2TL93	Frizzled/Smoothened family membrane region; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.938
NECAME_00266	NECAME_12243	W2TIJ5	W2T304	Frizzled/Smoothened family membrane region; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.975
NECAME_00266	NECAME_15775	W2TIJ5	W2SG65	Frizzled/Smoothened family membrane region; Belongs to the G-protein coupled receptor Fz/Smo family.	DIX domain protein.	0.951
NECAME_00266	NECAME_18220	W2TIJ5	W2TBK6	Frizzled/Smoothened family membrane region; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.606
NECAME_00266	NECAME_18705	W2TIJ5	W2SSU4	Frizzled/Smoothened family membrane region; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.768
NECAME_00267	NECAME_00266	W2TL93	W2TIJ5	Frizzled domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled/Smoothened family membrane region; Belongs to the G-protein coupled receptor Fz/Smo family.	0.938
NECAME_00267	NECAME_12243	W2TL93	W2T304	Frizzled domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.710
NECAME_00267	NECAME_15775	W2TL93	W2SG65	Frizzled domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	DIX domain protein.	0.536
NECAME_00267	NECAME_18220	W2TL93	W2TBK6	Frizzled domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.606
NECAME_00267	NECAME_18705	W2TL93	W2SSU4	Frizzled domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.768
NECAME_00268	NECAME_12243	W2TLL6	W2T304	FZ domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.606
NECAME_00268	NECAME_15775	W2TLL6	W2SG65	FZ domain-containing protein.	DIX domain protein.	0.536
NECAME_00268	NECAME_18220	W2TLL6	W2TBK6	FZ domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.606
NECAME_00268	NECAME_18705	W2TLL6	W2SSU4	FZ domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.712
NECAME_01685	NECAME_02546	W2TSA9	W2TD14	26S proteasome non-ATPase regulatory subunit 7 family protein.	Ribosomal protein L32.	0.999
NECAME_01685	NECAME_06456	W2TSA9	W2TW63	26S proteasome non-ATPase regulatory subunit 7 family protein.	Mov34/MPN/PAD-1 family protein.	0.999
NECAME_01685	NECAME_07456	W2TSA9	W2TNK2	26S proteasome non-ATPase regulatory subunit 7 family protein.	Ubiquitin-activating enzyme E1; Belongs to the ubiquitin-activating E1 family.	0.616
NECAME_01685	NECAME_14015	W2TSA9	W2STH3	26S proteasome non-ATPase regulatory subunit 7 family protein.	Cullin family protein; Belongs to the cullin family.	0.801
NECAME_02135	NECAME_02136	W2THC3	W2TJU8	Uncharacterized protein.	Uncharacterized protein.	0.918
NECAME_02135	NECAME_12243	W2THC3	W2T304	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.620