(19 nodes) rRNA catabolic process network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_06762	Uncharacterized protein. (207 aa)
	NECAME_06763	RNase_PH domain-containing protein. (95 aa)
	NECAME_04630	RNB-like protein; Belongs to the RNR ribonuclease family. (923 aa)
	NECAME_18584	PMC2NT domain protein. (119 aa)
	NECAME_04311	3' exoribonuclease family, domain 1. (324 aa)
	NECAME_04349	3' exoribonuclease family, domain 1. (304 aa)
	NECAME_04310	Uncharacterized protein. (222 aa)
	NECAME_12935	3' exoribonuclease family, domain 1. (431 aa)
	NECAME_12656	Uncharacterized protein. (110 aa)
	NECAME_12658	Uncharacterized protein. (169 aa)
	NECAME_12659	S1 motif domain-containing protein. (307 aa)
	NECAME_10615	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (417 aa)
	NECAME_18242	RNase_PH domain-containing protein. (209 aa)
	NECAME_08252	RNase_PH domain-containing protein. (131 aa)
	NECAME_07177	S1 domain-containing protein. (294 aa)
	NECAME_06654	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle. (686 aa)
	NECAME_06761	3'-5' exonuclease. (529 aa)
	NECAME_06655	SH3_12 domain-containing protein. (626 aa)
	NECAME_16261	Uncharacterized protein. (233 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_04310	NECAME_04349	W2SXE9	W2SX02	Uncharacterized protein.	3' exoribonuclease family, domain 1.	0.986
NECAME_04310	NECAME_04630	W2SXE9	W2SPZ0	Uncharacterized protein.	RNB-like protein; Belongs to the RNR ribonuclease family.	0.862
NECAME_04310	NECAME_06654	W2SXE9	W2TS22	Uncharacterized protein.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle.	0.661
NECAME_04310	NECAME_06655	W2SXE9	W2TUW0	Uncharacterized protein.	SH3_12 domain-containing protein.	0.661
NECAME_04310	NECAME_06761	W2SXE9	W2TUD3	Uncharacterized protein.	3'-5' exonuclease.	0.871
NECAME_04310	NECAME_06762	W2SXE9	W2TS62	Uncharacterized protein.	Uncharacterized protein.	0.871
NECAME_04310	NECAME_06763	W2SXE9	W2TSM3	Uncharacterized protein.	RNase_PH domain-containing protein.	0.982
NECAME_04310	NECAME_07177	W2SXE9	W2TQ79	Uncharacterized protein.	S1 domain-containing protein.	0.943
NECAME_04310	NECAME_08252	W2SXE9	W2TJK7	Uncharacterized protein.	RNase_PH domain-containing protein.	0.977
NECAME_04310	NECAME_12656	W2SXE9	W2T006	Uncharacterized protein.	Uncharacterized protein.	0.753
NECAME_04310	NECAME_12658	W2SXE9	W2T0Y2	Uncharacterized protein.	Uncharacterized protein.	0.753
NECAME_04310	NECAME_12659	W2SXE9	W2T1P3	Uncharacterized protein.	S1 motif domain-containing protein.	0.943
NECAME_04310	NECAME_12935	W2SXE9	W2SXX7	Uncharacterized protein.	3' exoribonuclease family, domain 1.	0.981
NECAME_04310	NECAME_16261	W2SXE9	W2TZQ8	Uncharacterized protein.	Uncharacterized protein.	0.881
NECAME_04310	NECAME_18242	W2SXE9	W2TAE4	Uncharacterized protein.	RNase_PH domain-containing protein.	0.881
NECAME_04310	NECAME_18584	W2SXE9	W2STL0	Uncharacterized protein.	PMC2NT domain protein.	0.871
NECAME_04311	NECAME_04349	W2SUY1	W2SX02	3' exoribonuclease family, domain 1.	3' exoribonuclease family, domain 1.	0.986
NECAME_04311	NECAME_04630	W2SUY1	W2SPZ0	3' exoribonuclease family, domain 1.	RNB-like protein; Belongs to the RNR ribonuclease family.	0.862
NECAME_04311	NECAME_06654	W2SUY1	W2TS22	3' exoribonuclease family, domain 1.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle.	0.661
NECAME_04311	NECAME_06655	W2SUY1	W2TUW0	3' exoribonuclease family, domain 1.	SH3_12 domain-containing protein.	0.661