(22 nodes) Negative regulation of macroautophagy network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_00398	Uncharacterized protein. (100 aa)
	NECAME_04687	Uncharacterized protein. (122 aa)
	NECAME_04686	Uncharacterized protein. (491 aa)
	NECAME_19284	FAT domain-containing protein. (159 aa)
	NECAME_04685	Uncharacterized protein. (178 aa)
	NECAME_18926	Uncharacterized protein. (169 aa)
	NECAME_18954	Uncharacterized protein. (160 aa)
	NECAME_18440	Serine/threonine-protein kinase TOR. (221 aa)
	NECAME_18872	Uncharacterized protein. (163 aa)
	NECAME_18346	Uncharacterized protein. (129 aa)
	NECAME_03442	Uncharacterized protein. (227 aa)
	NECAME_03440	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family. (927 aa)
	NECAME_03444	Uncharacterized protein. (188 aa)
	NECAME_10602	DUF3384 domain-containing protein. (568 aa)
	NECAME_17709	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family. (110 aa)
	NECAME_10603	Rap/ran-GAP. (849 aa)
	NECAME_17624	Uncharacterized protein. (195 aa)
	NECAME_17711	Uncharacterized protein. (226 aa)
	NECAME_00399	Uncharacterized protein. (159 aa)
	NECAME_02728	Uncharacterized protein. (397 aa)
	NECAME_17710	Rapamycin binding domain protein. (352 aa)
	NECAME_17708	Uncharacterized protein. (400 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_03440	NECAME_03442	W2T3M7	W2T3C5	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.751
NECAME_03440	NECAME_03444	W2T3M7	W2T6A5	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.659
NECAME_03440	NECAME_04685	W2T3M7	W2SQZ5	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.433
NECAME_03440	NECAME_04686	W2T3M7	W2SNK4	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.433
NECAME_03440	NECAME_04687	W2T3M7	W2SN56	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.433
NECAME_03440	NECAME_10602	W2T3M7	W2T7V2	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	DUF3384 domain-containing protein.	0.422
NECAME_03440	NECAME_10603	W2T3M7	W2TA64	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Rap/ran-GAP.	0.422
NECAME_03440	NECAME_17708	W2T3M7	W2TKY4	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.657
NECAME_03440	NECAME_19284	W2T3M7	W2SPA5	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	FAT domain-containing protein.	0.490
NECAME_03442	NECAME_03440	W2T3C5	W2T3M7	Uncharacterized protein.	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	0.751
NECAME_03442	NECAME_03444	W2T3C5	W2T6A5	Uncharacterized protein.	Uncharacterized protein.	0.642
NECAME_03442	NECAME_10602	W2T3C5	W2T7V2	Uncharacterized protein.	DUF3384 domain-containing protein.	0.422
NECAME_03442	NECAME_10603	W2T3C5	W2TA64	Uncharacterized protein.	Rap/ran-GAP.	0.422
NECAME_03444	NECAME_03440	W2T6A5	W2T3M7	Uncharacterized protein.	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	0.659
NECAME_03444	NECAME_03442	W2T6A5	W2T3C5	Uncharacterized protein.	Uncharacterized protein.	0.642
NECAME_03444	NECAME_04685	W2T6A5	W2SQZ5	Uncharacterized protein.	Uncharacterized protein.	0.433
NECAME_03444	NECAME_04686	W2T6A5	W2SNK4	Uncharacterized protein.	Uncharacterized protein.	0.433
NECAME_03444	NECAME_04687	W2T6A5	W2SN56	Uncharacterized protein.	Uncharacterized protein.	0.433
NECAME_03444	NECAME_10602	W2T6A5	W2T7V2	Uncharacterized protein.	DUF3384 domain-containing protein.	0.422
NECAME_03444	NECAME_10603	W2T6A5	W2TA64	Uncharacterized protein.	Rap/ran-GAP.	0.422