(13 nodes) NuRD complex network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_16723	Helicase ATP-binding domain-containing protein. (473 aa)
	NECAME_11462	MTA_R1 domain-containing protein. (168 aa)
	NECAME_16721	Uncharacterized protein. (210 aa)
	NECAME_11463	BAH domain protein. (403 aa)
	NECAME_04125	GATA zinc finger. (578 aa)
	NECAME_04127	Uncharacterized protein. (151 aa)
	NECAME_04124	Uncharacterized protein. (178 aa)
	NECAME_00807	WD domain, G-beta repeat protein. (416 aa)
	NECAME_14453	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (500 aa)
	NECAME_09291	Uncharacterized protein. (150 aa)
	NECAME_09289	P66_CC domain-containing protein. (352 aa)
	NECAME_09290	Uncharacterized protein. (167 aa)
	NECAME_16722	Uncharacterized protein. (128 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00807	NECAME_09289	W2SVZ9	W2TGC6	WD domain, G-beta repeat protein.	P66_CC domain-containing protein.	0.826
NECAME_00807	NECAME_09290	W2SVZ9	W2TGS7	WD domain, G-beta repeat protein.	Uncharacterized protein.	0.826
NECAME_00807	NECAME_09291	W2SVZ9	W2TEI2	WD domain, G-beta repeat protein.	Uncharacterized protein.	0.826
NECAME_00807	NECAME_11462	W2SVZ9	W2T720	WD domain, G-beta repeat protein.	MTA_R1 domain-containing protein.	0.967
NECAME_00807	NECAME_11463	W2SVZ9	W2T4H7	WD domain, G-beta repeat protein.	BAH domain protein.	0.967
NECAME_00807	NECAME_14453	W2SVZ9	W2SMH3	WD domain, G-beta repeat protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.939
NECAME_00807	NECAME_16721	W2SVZ9	W2TX52	WD domain, G-beta repeat protein.	Uncharacterized protein.	0.533
NECAME_00807	NECAME_16722	W2SVZ9	W2TUU5	WD domain, G-beta repeat protein.	Uncharacterized protein.	0.533
NECAME_00807	NECAME_16723	W2SVZ9	W2TVC3	WD domain, G-beta repeat protein.	Helicase ATP-binding domain-containing protein.	0.533
NECAME_04124	NECAME_04125	W2SWT2	W2SYS4	Uncharacterized protein.	GATA zinc finger.	0.664
NECAME_04124	NECAME_04127	W2SWT2	W2SX46	Uncharacterized protein.	Uncharacterized protein.	0.628
NECAME_04125	NECAME_04124	W2SYS4	W2SWT2	GATA zinc finger.	Uncharacterized protein.	0.664
NECAME_04125	NECAME_04127	W2SYS4	W2SX46	GATA zinc finger.	Uncharacterized protein.	0.739
NECAME_04127	NECAME_04124	W2SX46	W2SWT2	Uncharacterized protein.	Uncharacterized protein.	0.628
NECAME_04127	NECAME_04125	W2SX46	W2SYS4	Uncharacterized protein.	GATA zinc finger.	0.739
NECAME_09289	NECAME_00807	W2TGC6	W2SVZ9	P66_CC domain-containing protein.	WD domain, G-beta repeat protein.	0.826
NECAME_09289	NECAME_09290	W2TGC6	W2TGS7	P66_CC domain-containing protein.	Uncharacterized protein.	0.899
NECAME_09289	NECAME_09291	W2TGC6	W2TEI2	P66_CC domain-containing protein.	Uncharacterized protein.	0.887
NECAME_09289	NECAME_11462	W2TGC6	W2T720	P66_CC domain-containing protein.	MTA_R1 domain-containing protein.	0.674
NECAME_09289	NECAME_11463	W2TGC6	W2T4H7	P66_CC domain-containing protein.	BAH domain protein.	0.674