(178 nodes) Acyltransferase activity, transferring groups other than amino-acyl groups network (Necator americanus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_05362	Aminotransferase, class I/II. (610 aa)
	NECAME_15885	O-acyltransferase. (626 aa)
	NECAME_19487	Uncharacterized protein. (131 aa)
	NECAME_15874	Choline/Carnitine O-acyltransferase; Belongs to the carnitine/choline acetyltransferase family. (561 aa)
	NECAME_15365	Elongation of very long chain fatty acids protein. (209 aa)
	NECAME_05221	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (641 aa)
	NECAME_15192	Hydrolase, alpha/beta domain protein. (357 aa)
	NECAME_15146	MBOAT family protein; Belongs to the membrane-bound acyltransferase family. (281 aa)
	NECAME_05138	Diacylglycerol acyltransferase. (356 aa)
	NECAME_05133	Uncharacterized protein. (388 aa)
	NECAME_01117	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (518 aa)
	NECAME_00987	Beta-ketoacyl synthase protein. (164 aa)
	NECAME_14975	Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex. (511 aa)
	NECAME_00986	Beta-ketoacyl synthase protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (248 aa)
	NECAME_14897	Uncharacterized protein. (150 aa)
	NECAME_14911	Uncharacterized protein. (215 aa)
	NECAME_14896	Lecithin:cholesterol acyltransferase. (338 aa)
	NECAME_05183	O-acyltransferase. (467 aa)
	NECAME_14858	Uncharacterized protein. (207 aa)
	NECAME_14648	Uncharacterized protein. (184 aa)
	NECAME_14649	Uncharacterized protein. (119 aa)
	NECAME_04848	Uncharacterized protein. (762 aa)
	NECAME_00831	Acetyltransferase, GNAT family. (221 aa)
	NECAME_00852	Hat1_N domain-containing protein. (353 aa)
	NECAME_04626	Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. (292 aa)
	NECAME_14130	Acetyltransferase, GNAT family. (182 aa)
	NECAME_19210	Uncharacterized protein. (345 aa)
	NECAME_19203	Uncharacterized protein. (95 aa)
	NECAME_19083	Uncharacterized protein. (86 aa)
	NECAME_19054	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (60 aa)
	NECAME_19213	DUF3591 domain-containing protein. (144 aa)
	NECAME_19208	Uncharacterized protein. (345 aa)
	NECAME_13873	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (317 aa)
	NECAME_19122	Uncharacterized protein. (64 aa)
	NECAME_18691	Uncharacterized protein. (76 aa)
	NECAME_18650	Uncharacterized protein. (123 aa)
	NECAME_04222	DHHC zinc finger domain protein. (361 aa)
	NECAME_13530	Uncharacterized protein. (60 aa)
	NECAME_04120	Acyl_transf_3 domain-containing protein. (675 aa)
	NECAME_04057	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (338 aa)
	NECAME_03991	MBOAT family protein; Belongs to the membrane-bound acyltransferase family. (524 aa)
	NECAME_04021	Elongation of very long chain fatty acids protein. (301 aa)
	NECAME_13474	Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (212 aa)
	NECAME_12919	Beta-ketoacyl synthase protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (582 aa)
	NECAME_13175	Acetyl-CoA C-acetyltransferase. (764 aa)
	NECAME_12638	Uncharacterized protein. (406 aa)
	NECAME_13337	Uncharacterized protein. (147 aa)
	NECAME_12631	Carn_acyltransf domain-containing protein. (143 aa)
	NECAME_12530	Uncharacterized protein. (117 aa)
	NECAME_04035	Uncharacterized protein. (66 aa)
	NECAME_12680	Choline/Carnitine O-acyltransferase. (683 aa)
	NECAME_12632	Carn_acyltransf domain-containing protein. (157 aa)
	NECAME_00679	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (292 aa)
	NECAME_12529	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (276 aa)
	NECAME_03755	Uncharacterized protein. (173 aa)
	NECAME_12918	Beta-ketoacyl synthase protein. (2757 aa)
	NECAME_03748	Acetyltransferase, GNAT family. (197 aa)
	NECAME_12639	SAC3/GANP family protein. (542 aa)
	NECAME_12147	Uncharacterized protein. (125 aa)
	NECAME_03714	Choline/Carnitine O-acyltransferase. (352 aa)
	NECAME_03754	Acetyltransferase, GNAT family. (230 aa)
	NECAME_00663	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (318 aa)
	NECAME_11831	Uncharacterized protein. (75 aa)
	NECAME_03756	Acetyltransferase, GNAT family. (243 aa)
	NECAME_11832	Aminotran_1_2 domain-containing protein. (114 aa)
	NECAME_03354	DUF3591 domain-containing protein. (483 aa)
	NECAME_11775	Uncharacterized protein. (99 aa)
	NECAME_03352	Bromodomain protein. (268 aa)
	NECAME_11410	Uncharacterized protein. (72 aa)
	NECAME_11834	Aminotran_1_2 domain-containing protein. (205 aa)
	NECAME_11356	Transcriptional regulator, Sir2 family. (249 aa)
	NECAME_03353	Uncharacterized protein. (144 aa)
	NECAME_11777	Uncharacterized protein. (105 aa)
	NECAME_11392	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (59 aa)
	NECAME_11773	Uncharacterized protein. (68 aa)
	NECAME_11272	Uncharacterized protein. (119 aa)
	NECAME_03401	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (166 aa)
	NECAME_10790	MYST-type HAT domain-containing protein. (167 aa)
	NECAME_11409	Acetyltransferase, GNAT family. (161 aa)
	NECAME_10887	Glycine C-acetyltransferase. (398 aa)
	NECAME_10789	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (267 aa)
	NECAME_02978	Acetyltransferase, GNAT family. (229 aa)
	NECAME_18254	Uncharacterized protein. (161 aa)
	NECAME_10225	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (498 aa)
	NECAME_10787	Uncharacterized protein. (327 aa)
	NECAME_10127	Mak10 subunit, NatC N(Alpha)-terminal acetyltransferase. (503 aa)
	NECAME_00402	Peptidase, M22 family. (447 aa)
	NECAME_10088	GCP_C_terminal domain-containing protein. (351 aa)
	NECAME_10489	Aminotransferase, class I/II. (531 aa)
	NECAME_09992	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (462 aa)
	NECAME_00372	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (661 aa)
	NECAME_10330	Acetyltransferase, GNAT family. (200 aa)
	NECAME_00363	Acetyltransferase, GNAT family. (184 aa)
	NECAME_09686	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
	NECAME_18076	Carn_acyltransf domain-containing protein. (143 aa)
	NECAME_09778	Uncharacterized protein. (97 aa)
	NECAME_09618	Longevity-assurance protein. (102 aa)
	NECAME_00370	Diacylglycerol acyltransferase. (325 aa)
	NECAME_09464	Diacylglycerol acyltransferase. (103 aa)
	NECAME_09462	Diacylglycerol acyltransferase. (255 aa)
	NECAME_09463	Uncharacterized protein. (111 aa)
	NECAME_18049	Longevity-assurance protein. (116 aa)
	NECAME_09777	Uncharacterized protein. (1133 aa)
	NECAME_09531	Elongation of very long chain fatty acids protein. (316 aa)
	NECAME_02575	Uncharacterized protein. (575 aa)
	NECAME_02500	Acetyltransferase, GNAT family. (195 aa)
	NECAME_08917	Uncharacterized protein. (78 aa)
	NECAME_09057	Elongation of very long chain fatty acids protein. (267 aa)
	NECAME_09016	N-acetyltransferase domain-containing protein. (83 aa)
	NECAME_09021	N-acetyltransferase domain-containing protein. (73 aa)
	NECAME_08564	Longevity-assurance protein. (304 aa)
	NECAME_08182	Choline/Carnitine O-acyltransferase; Belongs to the carnitine/choline acetyltransferase family. (711 aa)
	NECAME_02161	Acyltransferase; Belongs to the GPAT/DAPAT family. (667 aa)
	NECAME_08389	Uncharacterized protein. (120 aa)
	NECAME_08371	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (430 aa)
	NECAME_07859	Uncharacterized protein. (132 aa)
	NECAME_08023	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (273 aa)
	NECAME_07734	Uncharacterized protein. (242 aa)
	NECAME_00282	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1034 aa)
	NECAME_08238	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (278 aa)
	NECAME_07915	Elongation of very long chain fatty acids protein. (381 aa)
	NECAME_01958	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (279 aa)
	NECAME_01968	Uncharacterized protein. (361 aa)
	NECAME_07540	Uncharacterized protein. (580 aa)
	NECAME_17626	AMP-binding enzyme. (1797 aa)
	NECAME_07742	Uncharacterized protein. (187 aa)
	NECAME_17627	Condensation domain-containing protein. (407 aa)
	NECAME_07707	N-acetyltransferase domain-containing protein. (263 aa)
	NECAME_07611	Elongation of very long chain fatty acids protein. (281 aa)
	NECAME_07539	Uncharacterized protein. (159 aa)
	NECAME_17482	Diacylglycerol kinase catalytic domain protein. (105 aa)
	NECAME_07267	Uncharacterized protein. (136 aa)
	NECAME_07403	SCP-2 sterol transfer family protein; Belongs to the thiolase-like superfamily. Thiolase family. (500 aa)
	NECAME_07740	TAZ zinc finger. (495 aa)
	NECAME_07162	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (458 aa)
	NECAME_07741	Bromodomain protein. (919 aa)
	NECAME_07265	PHD-finger. (157 aa)
	NECAME_07291	Tafazzin family protein; Belongs to the taffazin family. (308 aa)
	NECAME_17333	Uncharacterized protein. (92 aa)
	NECAME_07266	Uncharacterized protein. (399 aa)
	NECAME_07541	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (203 aa)
	NECAME_07542	Tudor-knot domain-containing protein. (158 aa)
	NECAME_17529	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (515 aa)
	NECAME_17481	Uncharacterized protein. (157 aa)
	NECAME_17211	Elongation of very long chain fatty acids protein. (199 aa)
	NECAME_07228	Uncharacterized protein; Belongs to the synaptobrevin family. (147 aa)
	NECAME_17304	Acyl_transf_3 domain-containing protein. (457 aa)
	NECAME_17319	Elongation of very long chain fatty acids protein. (291 aa)
	NECAME_07008	NRF domain-containing protein. (336 aa)
	NECAME_16983	Uncharacterized protein. (122 aa)
	NECAME_17168	Uncharacterized protein. (117 aa)
	NECAME_16830	Uncharacterized protein. (106 aa)
	NECAME_06438	PlsC domain-containing protein. (462 aa)
	NECAME_01566	Alpha-tubulin N-acetyltransferase; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynam [...] (275 aa)
	NECAME_06398	Elongation of very long chain fatty acids protein. (198 aa)
	NECAME_06243	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (554 aa)
	NECAME_01460	Acetyltransferase, GNAT family. (219 aa)
	NECAME_06236	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (113 aa)
	NECAME_06562	Bromodomain protein. (91 aa)
	NECAME_16462	Uncharacterized protein. (245 aa)
	NECAME_06563	PCAF protein. (283 aa)
	NECAME_16831	Acyl_transf_3 domain-containing protein. (163 aa)
	NECAME_06439	Uncharacterized protein. (175 aa)
	NECAME_16771	Uncharacterized protein. (319 aa)
	NECAME_06368	MBOAT family protein; Belongs to the membrane-bound acyltransferase family. (435 aa)
	NECAME_16340	Glycine C-acetyltransferase. (361 aa)
	NECAME_16115	Uncharacterized protein. (212 aa)
	NECAME_16664	Uncharacterized protein. (158 aa)
	NECAME_06136	Uncharacterized protein. (181 aa)
	NECAME_16113	Uncharacterized protein. (206 aa)
	NECAME_16493	MBOAT family protein; Belongs to the membrane-bound acyltransferase family. (440 aa)
	NECAME_19533	Uncharacterized protein. (102 aa)
	NECAME_16114	Uncharacterized protein. (166 aa)
	NECAME_01267	Choline/Carnitine O-acyltransferase. (635 aa)
	NECAME_06001	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (457 aa)
	NECAME_16352	Longevity-assurance protein. (287 aa)
	NECAME_05900	Uncharacterized protein. (173 aa)
	NECAME_05901	Uncharacterized protein. (139 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00282	NECAME_02500	W2TLA8	W2TFP8	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Acetyltransferase, GNAT family.	0.476
NECAME_00282	NECAME_03748	W2TLA8	W2T0Y3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Acetyltransferase, GNAT family.	0.548
NECAME_00282	NECAME_06562	W2TLA8	W2TVK3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Bromodomain protein.	0.413
NECAME_00282	NECAME_06563	W2TLA8	W2TVL9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	PCAF protein.	0.413
NECAME_00282	NECAME_07162	W2TLA8	W2TP56	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.	0.581
NECAME_00282	NECAME_14130	W2TLA8	W2SPT1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Acetyltransferase, GNAT family.	0.476
NECAME_00282	NECAME_16462	W2TLA8	W2TVL1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.688
NECAME_00282	NECAME_19122	W2TLA8	W2SST2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.413
NECAME_00363	NECAME_00831	W2TBL7	W2SNM1	Acetyltransferase, GNAT family.	Acetyltransferase, GNAT family.	0.628
NECAME_00363	NECAME_03748	W2TBL7	W2T0Y3	Acetyltransferase, GNAT family.	Acetyltransferase, GNAT family.	0.672
NECAME_00363	NECAME_10127	W2TBL7	W2TAD6	Acetyltransferase, GNAT family.	Mak10 subunit, NatC N(Alpha)-terminal acetyltransferase.	0.595
NECAME_00363	NECAME_10330	W2TBL7	W2TBD6	Acetyltransferase, GNAT family.	Acetyltransferase, GNAT family.	0.666
NECAME_00363	NECAME_11409	W2TBL7	W2T769	Acetyltransferase, GNAT family.	Acetyltransferase, GNAT family.	0.540
NECAME_00363	NECAME_11410	W2TBL7	W2T4M9	Acetyltransferase, GNAT family.	Uncharacterized protein.	0.540
NECAME_00363	NECAME_14130	W2TBL7	W2SPT1	Acetyltransferase, GNAT family.	Acetyltransferase, GNAT family.	0.665
NECAME_00370	NECAME_05183	W2TCS3	W2SL49	Diacylglycerol acyltransferase.	O-acyltransferase.	0.627
NECAME_00370	NECAME_14896	W2TCS3	W2SL20	Diacylglycerol acyltransferase.	Lecithin:cholesterol acyltransferase.	0.528
NECAME_00370	NECAME_14897	W2TCS3	W2SKP6	Diacylglycerol acyltransferase.	Uncharacterized protein.	0.528
NECAME_00370	NECAME_15885	W2TCS3	W2SFF0	Diacylglycerol acyltransferase.	O-acyltransferase.	0.657
NECAME_00372	NECAME_01267	W2TAW4	W2TZ11	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family.	Choline/Carnitine O-acyltransferase.	0.921