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NECAME_15184 NECAME_15184 NECAME_05305 NECAME_05305 NECAME_18415 NECAME_18415 NECAME_00797 NECAME_00797 NECAME_18684 NECAME_18684 NECAME_06099 NECAME_06099 NECAME_06655 NECAME_06655 NECAME_06761 NECAME_06761 NECAME_16781 NECAME_16781 NECAME_06762 NECAME_06762 NECAME_06654 NECAME_06654 NECAME_17109 NECAME_17109 NECAME_17380 NECAME_17380 NECAME_17676 NECAME_17676 NECAME_17677 NECAME_17677 NECAME_17803 NECAME_17803 NECAME_08628 NECAME_08628 NECAME_17999 NECAME_17999 NECAME_09619 NECAME_09619 NECAME_13634 NECAME_13634 NECAME_14808 NECAME_14808 NECAME_18584 NECAME_18584 NECAME_19202 NECAME_19202 NECAME_19337 NECAME_19337 NECAME_04630 NECAME_04630 NECAME_14974 NECAME_14974 NECAME_14523 NECAME_14523 NECAME_14973 NECAME_14973 NECAME_09486 NECAME_09486 NECAME_09621 NECAME_09621 NECAME_09828 NECAME_09828 NECAME_10285 NECAME_10285 NECAME_10694 NECAME_10694 NECAME_18203 NECAME_18203 NECAME_10696 NECAME_10696 NECAME_10695 NECAME_10695 NECAME_12022 NECAME_12022 NECAME_12742 NECAME_12742 NECAME_05543 NECAME_05543 NECAME_15881 NECAME_15881 NECAME_05304 NECAME_05304 NECAME_05276 NECAME_05276
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NECAME_15184DNA polymerase. (1051 aa)
NECAME_05305Exonuclease. (196 aa)
NECAME_18415DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (305 aa)
NECAME_00797DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (313 aa)
NECAME_18684DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (257 aa)
NECAME_06099CAF1 family ribonuclease. (312 aa)
NECAME_06655SH3_12 domain-containing protein. (626 aa)
NECAME_067613'-5' exonuclease. (529 aa)
NECAME_16781Exonuclease. (212 aa)
NECAME_06762Uncharacterized protein. (207 aa)
NECAME_066545'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle. (686 aa)
NECAME_17109Uncharacterized protein. (99 aa)
NECAME_17380Hydrolase, TatD family. (254 aa)
NECAME_17676DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (753 aa)
NECAME_17677DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (662 aa)
NECAME_17803XPG I-region. (389 aa)
NECAME_08628Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (597 aa)
NECAME_17999Uncharacterized protein. (99 aa)
NECAME_09619Putative polyribonucleotide nucleotidyltransferase. (443 aa)
NECAME_13634Leucine Rich repeat-containing domain protein. (728 aa)
NECAME_14808RNB-like protein; Belongs to the RNR ribonuclease family. (1185 aa)
NECAME_18584PMC2NT domain protein. (119 aa)
NECAME_19202Uncharacterized protein. (72 aa)
NECAME_19337Uncharacterized protein. (85 aa)
NECAME_04630RNB-like protein; Belongs to the RNR ribonuclease family. (923 aa)
NECAME_14974Uncharacterized protein. (534 aa)
NECAME_14523Uncharacterized protein. (126 aa)
NECAME_14973Uncharacterized protein. (413 aa)
NECAME_09486Apurinic endonuclease. (404 aa)
NECAME_09621RNase_PH_C domain-containing protein. (235 aa)
NECAME_09828Uncharacterized protein. (98 aa)
NECAME_10285Oligoribonuclease. (200 aa)
NECAME_10694Endo/exonuclease/phosphatase domain-containing protein. (360 aa)
NECAME_18203CAF1 family ribonuclease. (312 aa)
NECAME_10696Uncharacterized protein. (121 aa)
NECAME_10695Uncharacterized protein. (85 aa)
NECAME_12022DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (1038 aa)
NECAME_12742CAF1 family ribonuclease. (311 aa)
NECAME_05543Uncharacterized protein. (108 aa)
NECAME_15881Endonuclease/exonuclease/phosphatase family protein. (560 aa)
NECAME_05304Uncharacterized protein. (105 aa)
NECAME_052765'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle. (974 aa)
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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