(25 nodes) siRNA processing network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_11507	Uncharacterized protein. (278 aa)
	NECAME_19397	Uncharacterized protein. (166 aa)
	NECAME_14273	Double stranded RNA binding domain protein; Belongs to the helicase family. Dicer subfamily. (830 aa)
	NECAME_13832	DEAD/DEAH box helicase. (1028 aa)
	NECAME_12816	DRBM domain-containing protein. (95 aa)
	NECAME_12817	DRBM domain-containing protein. (151 aa)
	NECAME_06467	RNA-dependent RNA polymerase. (270 aa)
	NECAME_11509	Uncharacterized protein. (86 aa)
	NECAME_06466	RNA-dependent RNA polymerase. (108 aa)
	NECAME_06464	Uncharacterized protein. (198 aa)
	NECAME_11508	RNA-dependent RNA polymerase. (354 aa)
	NECAME_11503	RNA-dependent RNA polymerase. (186 aa)
	NECAME_11506	Uncharacterized protein. (456 aa)
	NECAME_11510	RNA-dependent RNA polymerase. (672 aa)
	NECAME_11505	RNA-dependent RNA polymerase. (200 aa)
	NECAME_14275	RNase3 domain protein. (405 aa)
	NECAME_14274	Uncharacterized protein. (374 aa)
	NECAME_06468	RNA-dependent RNA polymerase. (120 aa)
	NECAME_06465	RNA-dependent RNA polymerase. (202 aa)
	NECAME_18093	Uncharacterized protein. (67 aa)
	NECAME_05906	RNase_Zc3h12a domain-containing protein. (115 aa)
	NECAME_06405	Helicase protein. (348 aa)
	NECAME_00876	Uncharacterized protein. (69 aa)
	NECAME_00875	Uncharacterized protein. (156 aa)
	NECAME_11504	RNA-dependent RNA polymerase. (168 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_06405	NECAME_12816	W2TWJ6	W2SY38	Helicase protein.	DRBM domain-containing protein.	0.459
NECAME_06405	NECAME_12817	W2TWJ6	W2SYH0	Helicase protein.	DRBM domain-containing protein.	0.459
NECAME_06464	NECAME_06465	W2TUK0	W2TTB3	Uncharacterized protein.	RNA-dependent RNA polymerase.	0.626
NECAME_06465	NECAME_06464	W2TTB3	W2TUK0	RNA-dependent RNA polymerase.	Uncharacterized protein.	0.626
NECAME_06465	NECAME_06466	W2TTB3	W2TW73	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.880
NECAME_06465	NECAME_06467	W2TTB3	W2TWC7	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.939
NECAME_06465	NECAME_11505	W2TTB3	W2T415	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.731
NECAME_06465	NECAME_11508	W2TTB3	W2T652	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.519
NECAME_06466	NECAME_06465	W2TW73	W2TTB3	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.880
NECAME_06466	NECAME_06467	W2TW73	W2TWC7	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.924
NECAME_06466	NECAME_11503	W2TW73	W2T647	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.484
NECAME_06466	NECAME_11508	W2TW73	W2T652	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.856
NECAME_06467	NECAME_06465	W2TWC7	W2TTB3	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.939
NECAME_06467	NECAME_06466	W2TWC7	W2TW73	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.924
NECAME_06467	NECAME_06468	W2TWC7	W2TU56	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.700
NECAME_06467	NECAME_11503	W2TWC7	W2T647	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.485
NECAME_06467	NECAME_11505	W2TWC7	W2T415	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.950
NECAME_06467	NECAME_11506	W2TWC7	W2T4Y6	RNA-dependent RNA polymerase.	Uncharacterized protein.	0.575
NECAME_06467	NECAME_11510	W2TWC7	W2T421	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.878
NECAME_06468	NECAME_06467	W2TU56	W2TWC7	RNA-dependent RNA polymerase.	RNA-dependent RNA polymerase.	0.700