(6 nodes) TSC1-TSC2 complex network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_04687	Uncharacterized protein. (122 aa)
	NECAME_04685	Uncharacterized protein. (178 aa)
	NECAME_11530	Uncharacterized protein. (303 aa)
	NECAME_10602	DUF3384 domain-containing protein. (568 aa)
	NECAME_10603	Rap/ran-GAP. (849 aa)
	NECAME_04686	Uncharacterized protein. (491 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_04685	NECAME_10602	W2SQZ5	W2T7V2	Uncharacterized protein.	DUF3384 domain-containing protein.	0.864
NECAME_04685	NECAME_10603	W2SQZ5	W2TA64	Uncharacterized protein.	Rap/ran-GAP.	0.864
NECAME_04685	NECAME_11530	W2SQZ5	W2T3Z4	Uncharacterized protein.	Uncharacterized protein.	0.926
NECAME_04686	NECAME_04687	W2SNK4	W2SN56	Uncharacterized protein.	Uncharacterized protein.	0.499
NECAME_04686	NECAME_10602	W2SNK4	W2T7V2	Uncharacterized protein.	DUF3384 domain-containing protein.	0.864
NECAME_04686	NECAME_10603	W2SNK4	W2TA64	Uncharacterized protein.	Rap/ran-GAP.	0.864
NECAME_04686	NECAME_11530	W2SNK4	W2T3Z4	Uncharacterized protein.	Uncharacterized protein.	0.926
NECAME_04687	NECAME_04686	W2SN56	W2SNK4	Uncharacterized protein.	Uncharacterized protein.	0.499
NECAME_04687	NECAME_10602	W2SN56	W2T7V2	Uncharacterized protein.	DUF3384 domain-containing protein.	0.864
NECAME_04687	NECAME_10603	W2SN56	W2TA64	Uncharacterized protein.	Rap/ran-GAP.	0.864
NECAME_04687	NECAME_11530	W2SN56	W2T3Z4	Uncharacterized protein.	Uncharacterized protein.	0.926
NECAME_10602	NECAME_04685	W2T7V2	W2SQZ5	DUF3384 domain-containing protein.	Uncharacterized protein.	0.864
NECAME_10602	NECAME_04686	W2T7V2	W2SNK4	DUF3384 domain-containing protein.	Uncharacterized protein.	0.864
NECAME_10602	NECAME_04687	W2T7V2	W2SN56	DUF3384 domain-containing protein.	Uncharacterized protein.	0.864
NECAME_10602	NECAME_10603	W2T7V2	W2TA64	DUF3384 domain-containing protein.	Rap/ran-GAP.	0.897
NECAME_10602	NECAME_11530	W2T7V2	W2T3Z4	DUF3384 domain-containing protein.	Uncharacterized protein.	0.994
NECAME_10603	NECAME_04685	W2TA64	W2SQZ5	Rap/ran-GAP.	Uncharacterized protein.	0.864
NECAME_10603	NECAME_04686	W2TA64	W2SNK4	Rap/ran-GAP.	Uncharacterized protein.	0.864
NECAME_10603	NECAME_04687	W2TA64	W2SN56	Rap/ran-GAP.	Uncharacterized protein.	0.864
NECAME_10603	NECAME_10602	W2TA64	W2T7V2	Rap/ran-GAP.	DUF3384 domain-containing protein.	0.897