(14 nodes) Receptor clustering network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_16668	Carboxylesterase. (359 aa)
	NECAME_14884	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (593 aa)
	NECAME_19388	Uncharacterized protein. (82 aa)
	NECAME_19030	Uncharacterized protein. (74 aa)
	NECAME_18919	DUF3694 domain-containing protein. (71 aa)
	NECAME_12673	Arfaptin-like domain protein. (320 aa)
	NECAME_00320	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (771 aa)
	NECAME_09940	PDZ/DHR/GLGF domain protein. (269 aa)
	NECAME_08487	Leucine Rich repeat-containing domain protein. (426 aa)
	NECAME_08351	Guanylate kinase-like domain-containing protein. (94 aa)
	NECAME_08500	FERM protein. (1073 aa)
	NECAME_08367	PDZ/DHR/GLGF domain protein; Belongs to the MAGUK family. (972 aa)
	NECAME_08350	Variant SH3 domain protein. (278 aa)
	NECAME_00155	Uncharacterized protein. (894 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00155	NECAME_08350	W2U1Q5	W2TKU2	Uncharacterized protein.	Variant SH3 domain protein.	0.972
NECAME_00155	NECAME_08351	W2U1Q5	W2TIL2	Uncharacterized protein.	Guanylate kinase-like domain-containing protein.	0.972
NECAME_08350	NECAME_00155	W2TKU2	W2U1Q5	Variant SH3 domain protein.	Uncharacterized protein.	0.972
NECAME_08350	NECAME_08351	W2TKU2	W2TIL2	Variant SH3 domain protein.	Guanylate kinase-like domain-containing protein.	0.985
NECAME_08350	NECAME_08367	W2TKU2	W2TKS2	Variant SH3 domain protein.	PDZ/DHR/GLGF domain protein; Belongs to the MAGUK family.	0.886
NECAME_08350	NECAME_08487	W2TKU2	W2THX2	Variant SH3 domain protein.	Leucine Rich repeat-containing domain protein.	0.990
NECAME_08350	NECAME_09940	W2TKU2	W2TAW0	Variant SH3 domain protein.	PDZ/DHR/GLGF domain protein.	0.506
NECAME_08350	NECAME_16668	W2TKU2	W2TVU8	Variant SH3 domain protein.	Carboxylesterase.	0.462
NECAME_08350	NECAME_19388	W2TKU2	W2SP96	Variant SH3 domain protein.	Uncharacterized protein.	0.972
NECAME_08351	NECAME_00155	W2TIL2	W2U1Q5	Guanylate kinase-like domain-containing protein.	Uncharacterized protein.	0.972
NECAME_08351	NECAME_08350	W2TIL2	W2TKU2	Guanylate kinase-like domain-containing protein.	Variant SH3 domain protein.	0.985
NECAME_08351	NECAME_08367	W2TIL2	W2TKS2	Guanylate kinase-like domain-containing protein.	PDZ/DHR/GLGF domain protein; Belongs to the MAGUK family.	0.886
NECAME_08351	NECAME_08487	W2TIL2	W2THX2	Guanylate kinase-like domain-containing protein.	Leucine Rich repeat-containing domain protein.	0.990
NECAME_08351	NECAME_09940	W2TIL2	W2TAW0	Guanylate kinase-like domain-containing protein.	PDZ/DHR/GLGF domain protein.	0.506
NECAME_08351	NECAME_16668	W2TIL2	W2TVU8	Guanylate kinase-like domain-containing protein.	Carboxylesterase.	0.462
NECAME_08351	NECAME_19388	W2TIL2	W2SP96	Guanylate kinase-like domain-containing protein.	Uncharacterized protein.	0.972
NECAME_08367	NECAME_08350	W2TKS2	W2TKU2	PDZ/DHR/GLGF domain protein; Belongs to the MAGUK family.	Variant SH3 domain protein.	0.886
NECAME_08367	NECAME_08351	W2TKS2	W2TIL2	PDZ/DHR/GLGF domain protein; Belongs to the MAGUK family.	Guanylate kinase-like domain-containing protein.	0.886
NECAME_08367	NECAME_08487	W2TKS2	W2THX2	PDZ/DHR/GLGF domain protein; Belongs to the MAGUK family.	Leucine Rich repeat-containing domain protein.	0.792
NECAME_08487	NECAME_08350	W2THX2	W2TKU2	Leucine Rich repeat-containing domain protein.	Variant SH3 domain protein.	0.990