(67 nodes) Meiotic chromosome segregation network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_01324	Uncharacterized protein. (164 aa)
	NECAME_05409	Protein kinase domain-containing protein. (214 aa)
	NECAME_15270	Uncharacterized protein. (173 aa)
	NECAME_15269	Peptidase family C50. (175 aa)
	NECAME_15152	Uncharacterized protein. (159 aa)
	NECAME_14593	Uncharacterized protein. (175 aa)
	NECAME_00878	Uncharacterized protein. (149 aa)
	NECAME_14594	Uncharacterized protein. (61 aa)
	NECAME_04636	Uncharacterized protein. (82 aa)
	NECAME_13857	Uncharacterized protein. (146 aa)
	NECAME_13858	Protein kinase domain-containing protein. (315 aa)
	NECAME_13795	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (284 aa)
	NECAME_18918	Uncharacterized protein. (83 aa)
	NECAME_13460	HEAT repeat protein. (595 aa)
	NECAME_18593	Peptidase family C50. (162 aa)
	NECAME_13415	Uncharacterized protein. (804 aa)
	NECAME_13463	Uncharacterized protein. (617 aa)
	NECAME_13461	Uncharacterized protein. (83 aa)
	NECAME_12669	SAP domain-containing protein. (267 aa)
	NECAME_13230	SprT-like domain-containing protein. (229 aa)
	NECAME_04080	Uncharacterized protein. (163 aa)
	NECAME_12397	Uncharacterized protein. (71 aa)
	NECAME_04081	Uncharacterized protein. (659 aa)
	NECAME_12524	Uncharacterized protein. (754 aa)
	NECAME_11538	Cullin family protein; Belongs to the cullin family. (498 aa)
	NECAME_11109	Timeless protein. (580 aa)
	NECAME_03141	Uncharacterized protein. (224 aa)
	NECAME_11276	Uncharacterized protein. (144 aa)
	NECAME_03139	Uncharacterized protein. (568 aa)
	NECAME_11108	TIMELESS_C domain-containing protein. (400 aa)
	NECAME_03086	STAG domain protein. (1033 aa)
	NECAME_03140	Uncharacterized protein. (218 aa)
	NECAME_03087	Uncharacterized protein. (64 aa)
	NECAME_10714	DNA gyrase/topoisomerase IV, A subunit. (1495 aa)
	NECAME_10365	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1395 aa)
	NECAME_00379	Uncharacterized protein. (207 aa)
	NECAME_00412	Uncharacterized protein. (131 aa)
	NECAME_02674	Uncharacterized protein. (364 aa)
	NECAME_10130	Kinase domain protein. (273 aa)
	NECAME_02675	Cnd1 domain-containing protein. (859 aa)
	NECAME_00380	Uncharacterized protein. (716 aa)
	NECAME_00409	PAP/25A associated domain protein. (168 aa)
	NECAME_05772	Nipped-B protein. (1911 aa)
	NECAME_09204	RING-type domain-containing protein. (172 aa)
	NECAME_02319	Cyclin domain protein; Belongs to the cyclin family. (268 aa)
	NECAME_08758	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (211 aa)
	NECAME_08040	RMI1_C domain-containing protein. (277 aa)
	NECAME_07971	MutS domain V protein. (806 aa)
	NECAME_07714	Uncharacterized protein. (424 aa)
	NECAME_07530	Cnd1 domain-containing protein. (238 aa)
	NECAME_07713	Uncharacterized protein. (423 aa)
	NECAME_17578	Uncharacterized protein. (116 aa)
	NECAME_08039	DUF1767 domain-containing protein. (336 aa)
	NECAME_07528	Uncharacterized protein. (157 aa)
	NECAME_17579	Helicase ATP-binding domain-containing protein. (131 aa)
	NECAME_07529	Uncharacterized protein. (472 aa)
	NECAME_07716	Uncharacterized protein. (498 aa)
	NECAME_07240	Meiotic recombinase Dmc1; Belongs to the RecA family. (345 aa)
	NECAME_01737	ERCC4 domain protein. (267 aa)
	NECAME_07440	Uncharacterized protein. (184 aa)
	NECAME_16570	Uncharacterized protein. (371 aa)
	NECAME_16462	Uncharacterized protein. (245 aa)
	NECAME_05879	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (883 aa)
	NECAME_16617	PDZ/DHR/GLGF domain protein. (269 aa)
	NECAME_06096	MutS domain V protein. (288 aa)
	NECAME_06097	MutS_IV domain-containing protein. (221 aa)
	NECAME_16463	Tat binding protein 1(TBP-1)-interacting protein. (190 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00379	NECAME_00380	W2TAE2	W2TCT2	Uncharacterized protein.	Uncharacterized protein.	0.601
NECAME_00380	NECAME_00379	W2TCT2	W2TAE2	Uncharacterized protein.	Uncharacterized protein.	0.601
NECAME_00878	NECAME_01324	W2SNC9	W2TYR0	Uncharacterized protein.	Uncharacterized protein.	0.496
NECAME_00878	NECAME_01737	W2SNC9	W2TQJ1	Uncharacterized protein.	ERCC4 domain protein.	0.915
NECAME_00878	NECAME_03139	W2SNC9	W2T6G5	Uncharacterized protein.	Uncharacterized protein.	0.570
NECAME_00878	NECAME_03140	W2SNC9	W2T766	Uncharacterized protein.	Uncharacterized protein.	0.570
NECAME_00878	NECAME_03141	W2SNC9	W2T637	Uncharacterized protein.	Uncharacterized protein.	0.570
NECAME_00878	NECAME_04080	W2SNC9	W2SZJ0	Uncharacterized protein.	Uncharacterized protein.	0.496
NECAME_00878	NECAME_04081	W2SNC9	W2T0A9	Uncharacterized protein.	Uncharacterized protein.	0.496
NECAME_00878	NECAME_05879	W2SNC9	W2TWW6	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.797
NECAME_00878	NECAME_06096	W2SNC9	W2TY93	Uncharacterized protein.	MutS domain V protein.	0.500
NECAME_00878	NECAME_06097	W2SNC9	W2TYC2	Uncharacterized protein.	MutS_IV domain-containing protein.	0.500
NECAME_00878	NECAME_07240	W2SNC9	W2TPS1	Uncharacterized protein.	Meiotic recombinase Dmc1; Belongs to the RecA family.	0.969
NECAME_00878	NECAME_07971	W2SNC9	W2TKX5	Uncharacterized protein.	MutS domain V protein.	0.608
NECAME_00878	NECAME_08039	W2SNC9	W2TMV9	Uncharacterized protein.	DUF1767 domain-containing protein.	0.716
NECAME_00878	NECAME_08040	W2SNC9	W2TKN3	Uncharacterized protein.	RMI1_C domain-containing protein.	0.716
NECAME_00878	NECAME_08758	W2SNC9	W2TIR7	Uncharacterized protein.	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.	0.660
NECAME_00878	NECAME_10365	W2SNC9	W2T8R7	Uncharacterized protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.421
NECAME_00878	NECAME_10714	W2SNC9	W2T8F4	Uncharacterized protein.	DNA gyrase/topoisomerase IV, A subunit.	0.421
NECAME_00878	NECAME_12524	W2SNC9	W2T1D7	Uncharacterized protein.	Uncharacterized protein.	0.558