(25 nodes) Phagocytic vesicle network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_01442	PX domain protein. (425 aa)
	NECAME_16212	Uncharacterized protein. (157 aa)
	NECAME_10184	Uncharacterized protein. (54 aa)
	NECAME_11138	WD domain, G-beta repeat protein. (295 aa)
	NECAME_12443	Ras family protein. (207 aa)
	NECAME_13711	Gamma-aminobutyric acid receptor-associated protein. (118 aa)
	NECAME_00828	Phosphotyrosine interaction domain protein. (436 aa)
	NECAME_16011	ENTH domain protein. (465 aa)
	NECAME_15703	Uncharacterized protein. (338 aa)
	NECAME_14543	Putative cystinosin. (368 aa)
	NECAME_15388	EGF-like domain protein. (529 aa)
	NECAME_15702	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1282 aa)
	NECAME_15389	EGF-like domain protein. (529 aa)
	NECAME_10186	PX domain protein. (167 aa)
	NECAME_09622	Lysosome-associated membrane glycoprotein. (264 aa)
	NECAME_02515	FG-GAP repeat protein; Belongs to the integrin alpha chain family. (938 aa)
	NECAME_10185	Uncharacterized protein. (179 aa)
	NECAME_09722	Uncharacterized protein. (182 aa)
	NECAME_09933	Uncharacterized protein. (1167 aa)
	NECAME_09053	Uncharacterized protein. (429 aa)
	NECAME_10183	Vps5 domain-containing protein. (107 aa)
	NECAME_08550	Ras family protein. (152 aa)
	NECAME_02194	Papain family cysteine protease; Belongs to the peptidase C1 family. (352 aa)
	NECAME_06737	PX domain protein. (508 aa)
	NECAME_01544	Ras family protein. (212 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00828	NECAME_02515	W2SNA1	W2TFR3	Phosphotyrosine interaction domain protein.	FG-GAP repeat protein; Belongs to the integrin alpha chain family.	0.407
NECAME_00828	NECAME_08550	W2SNA1	W2TID4	Phosphotyrosine interaction domain protein.	Ras family protein.	0.575
NECAME_00828	NECAME_15388	W2SNA1	W2SIF1	Phosphotyrosine interaction domain protein.	EGF-like domain protein.	0.554
NECAME_00828	NECAME_15389	W2SNA1	W2SI61	Phosphotyrosine interaction domain protein.	EGF-like domain protein.	0.554
NECAME_01442	NECAME_06737	W2TWV3	W2TUH5	PX domain protein.	PX domain protein.	0.741
NECAME_01442	NECAME_08550	W2TWV3	W2TID4	PX domain protein.	Ras family protein.	0.802
NECAME_01442	NECAME_09053	W2TWV3	W2THJ7	PX domain protein.	Uncharacterized protein.	0.406
NECAME_01442	NECAME_09933	W2TWV3	W2TAZ7	PX domain protein.	Uncharacterized protein.	0.656
NECAME_01442	NECAME_10183	W2TWV3	W2TAY7	PX domain protein.	Vps5 domain-containing protein.	0.886
NECAME_01442	NECAME_10184	W2TWV3	W2T9P9	PX domain protein.	Uncharacterized protein.	0.886
NECAME_01442	NECAME_10185	W2TWV3	W2TC41	PX domain protein.	Uncharacterized protein.	0.886
NECAME_01442	NECAME_10186	W2TWV3	W2TCL4	PX domain protein.	PX domain protein.	0.886
NECAME_01442	NECAME_11138	W2TWV3	W2T6V2	PX domain protein.	WD domain, G-beta repeat protein.	0.681
NECAME_01442	NECAME_12443	W2TWV3	W2T1B4	PX domain protein.	Ras family protein.	0.591
NECAME_01442	NECAME_13711	W2TWV3	W2STQ2	PX domain protein.	Gamma-aminobutyric acid receptor-associated protein.	0.531
NECAME_01442	NECAME_15702	W2TWV3	W2SGG9	PX domain protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.602
NECAME_01442	NECAME_15703	W2TWV3	W2SG93	PX domain protein.	Uncharacterized protein.	0.602
NECAME_01544	NECAME_08550	W2TVA7	W2TID4	Ras family protein.	Ras family protein.	0.701
NECAME_01544	NECAME_09053	W2TVA7	W2THJ7	Ras family protein.	Uncharacterized protein.	0.472
NECAME_01544	NECAME_09933	W2TVA7	W2TAZ7	Ras family protein.	Uncharacterized protein.	0.437