(4 nodes) Farnesyl diphosphate biosynthetic process network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_00802	Uncharacterized protein. (157 aa)
	NECAME_02601	Uncharacterized protein. (160 aa)
	NECAME_06853	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (310 aa)
	NECAME_06852	HMG_CoA_synt_C domain-containing protein. (103 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00802	NECAME_02601	W2SVZ3	W2TCC0	Uncharacterized protein.	Uncharacterized protein.	0.909
NECAME_00802	NECAME_06852	W2SVZ3	W2TTV6	Uncharacterized protein.	HMG_CoA_synt_C domain-containing protein.	0.805
NECAME_00802	NECAME_06853	W2SVZ3	W2TTZ9	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.805
NECAME_02601	NECAME_00802	W2TCC0	W2SVZ3	Uncharacterized protein.	Uncharacterized protein.	0.909
NECAME_02601	NECAME_06852	W2TCC0	W2TTV6	Uncharacterized protein.	HMG_CoA_synt_C domain-containing protein.	0.646
NECAME_02601	NECAME_06853	W2TCC0	W2TTZ9	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.646
NECAME_06852	NECAME_00802	W2TTV6	W2SVZ3	HMG_CoA_synt_C domain-containing protein.	Uncharacterized protein.	0.805
NECAME_06852	NECAME_02601	W2TTV6	W2TCC0	HMG_CoA_synt_C domain-containing protein.	Uncharacterized protein.	0.646
NECAME_06853	NECAME_00802	W2TTZ9	W2SVZ3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.805
NECAME_06853	NECAME_02601	W2TTZ9	W2TCC0	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.646