(86 nodes) Positive regulation of behavior network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_18400	Uncharacterized protein. (95 aa)
	NECAME_15800	MIR domain protein. (1488 aa)
	NECAME_15079	Uncharacterized protein. (71 aa)
	NECAME_15062	EGF-like domain protein. (419 aa)
	NECAME_15061	Calcium binding EGF domain protein. (176 aa)
	NECAME_15020	Collagen triple helix repeat protein. (340 aa)
	NECAME_14958	Uncharacterized protein. (121 aa)
	NECAME_14884	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (593 aa)
	NECAME_19424	DUF667 domain-containing protein. (171 aa)
	NECAME_15077	Kinase domain protein; Belongs to the protein kinase superfamily. (341 aa)
	NECAME_14513	Uncharacterized protein. (66 aa)
	NECAME_01014	Vps51/Vps67. (990 aa)
	NECAME_14509	Uncharacterized protein. (78 aa)
	NECAME_14959	Uncharacterized protein. (90 aa)
	NECAME_14512	PHB domain-containing protein. (83 aa)
	NECAME_14511	PHB domain-containing protein. (118 aa)
	NECAME_19030	Uncharacterized protein. (74 aa)
	NECAME_18919	DUF3694 domain-containing protein. (71 aa)
	NECAME_04603	Trypsin; Belongs to the peptidase S1 family. (257 aa)
	NECAME_19176	Matrixin. (60 aa)
	NECAME_04343	Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (132 aa)
	NECAME_13475	Uncharacterized protein. (170 aa)
	NECAME_00814	Mago nashi protein. (153 aa)
	NECAME_18581	DUF4071 domain-containing protein. (122 aa)
	NECAME_13640	Membrane-associated protein gex-3 family protein. (865 aa)
	NECAME_13202	WH1 domain protein. (460 aa)
	NECAME_13091	SPFH/Band 7/PHB domain protein. (189 aa)
	NECAME_12953	Peptidase, S8/S53 family. (265 aa)
	NECAME_12902	Uncharacterized protein. (251 aa)
	NECAME_12979	Uncharacterized protein. (397 aa)
	NECAME_12954	S8_pro-domain domain-containing protein. (116 aa)
	NECAME_00801	Uncharacterized protein. (360 aa)
	NECAME_12436	Rab-GAP TBC domain-containing protein. (107 aa)
	NECAME_04026	Matrixin. (223 aa)
	NECAME_12434	TBC domain protein. (247 aa)
	NECAME_12180	Uncharacterized protein. (164 aa)
	NECAME_03687	Uncharacterized protein. (200 aa)
	NECAME_12183	Protein kinase domain-containing protein. (142 aa)
	NECAME_03558	Laminin G domain protein. (536 aa)
	NECAME_03556	Laminin G domain protein. (315 aa)
	NECAME_12179	WD domain, G-beta repeat protein. (150 aa)
	NECAME_12184	Uncharacterized protein. (208 aa)
	NECAME_12033	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (575 aa)
	NECAME_12181	Uncharacterized protein. (138 aa)
	NECAME_11860	Peptidase_M14 domain-containing protein. (427 aa)
	NECAME_12182	Uncharacterized protein. (259 aa)
	NECAME_11428	Helix-loop-helix DNA-binding domain protein. (159 aa)
	NECAME_03470	Transporter, major facilitator family protein. (487 aa)
	NECAME_10923	F-BAR domain-containing protein. (236 aa)
	NECAME_11031	Phosphodiesterase. (620 aa)
	NECAME_02902	Aldo_ket_red domain-containing protein. (123 aa)
	NECAME_02901	Aldo_ket_red domain-containing protein. (248 aa)
	NECAME_10337	PHB domain-containing protein. (77 aa)
	NECAME_09992	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (462 aa)
	NECAME_10395	Ubiquitinyl hydrolase 1. (387 aa)
	NECAME_10335	Uncharacterized protein. (108 aa)
	NECAME_09540	Vps52 / Sac2 family protein. (698 aa)
	NECAME_02390	RUN domain-containing protein. (542 aa)
	NECAME_09083	NOL1/NOP2/sun family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (694 aa)
	NECAME_09012	Degenerin; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (589 aa)
	NECAME_02550	Uncharacterized protein. (114 aa)
	NECAME_02458	Uncharacterized protein. (249 aa)
	NECAME_09572	Vps53-like protein. (868 aa)
	NECAME_08778	Uncharacterized protein. (247 aa)
	NECAME_08817	DUF2451 domain-containing protein. (124 aa)
	NECAME_08776	Uncharacterized protein. (248 aa)
	NECAME_08818	Vps54_N domain-containing protein. (551 aa)
	NECAME_08777	Uncharacterized protein. (261 aa)
	NECAME_08779	Uncharacterized protein. (425 aa)
	NECAME_08816	DUF2451 domain-containing protein. (80 aa)
	NECAME_08671	Neur_chan_LBD domain-containing protein. (361 aa)
	NECAME_02048	G_PROTEIN_RECEP_F1_2 domain-containing protein. (254 aa)
	NECAME_08048	WD domain, G-beta repeat protein. (652 aa)
	NECAME_02049	Uncharacterized protein. (186 aa)
	NECAME_07710	Runt domain protein. (158 aa)
	NECAME_17331	Uncharacterized protein. (179 aa)
	NECAME_07288	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (207 aa)
	NECAME_07286	Degenerin; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (757 aa)
	NECAME_01649	Uncharacterized protein. (168 aa)
	NECAME_01536	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (433 aa)
	NECAME_01431	HMG box. (438 aa)
	NECAME_16532	Sodium-dependent noradrenaline transporter domain protein. (260 aa)
	NECAME_06078	WD domain, G-beta repeat protein. (243 aa)
	NECAME_16586	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (750 aa)
	NECAME_00159	Kinase domain protein; Belongs to the protein kinase superfamily. (347 aa)
	NECAME_16147	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1283 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00159	NECAME_15077	W2TZ17	W2SM85	Kinase domain protein; Belongs to the protein kinase superfamily.	Kinase domain protein; Belongs to the protein kinase superfamily.	0.721
NECAME_00159	NECAME_15079	W2TZ17	W2SJK9	Kinase domain protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.679
NECAME_00159	NECAME_18581	W2TZ17	W2SVX5	Kinase domain protein; Belongs to the protein kinase superfamily.	DUF4071 domain-containing protein.	0.679
NECAME_00801	NECAME_10923	W2SYK0	W2T6T6	Uncharacterized protein.	F-BAR domain-containing protein.	0.577
NECAME_00801	NECAME_13202	W2SYK0	W2SX37	Uncharacterized protein.	WH1 domain protein.	0.800
NECAME_00801	NECAME_13640	W2SYK0	W2SW99	Uncharacterized protein.	Membrane-associated protein gex-3 family protein.	0.992
NECAME_00801	NECAME_16147	W2SYK0	W2U0B9	Uncharacterized protein.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.992
NECAME_01014	NECAME_02390	W2SMG9	W2TEN1	Vps51/Vps67.	RUN domain-containing protein.	0.612
NECAME_01014	NECAME_06078	W2SMG9	W2TVH8	Vps51/Vps67.	WD domain, G-beta repeat protein.	0.891
NECAME_01014	NECAME_08816	W2SMG9	W2TIX0	Vps51/Vps67.	DUF2451 domain-containing protein.	0.857
NECAME_01014	NECAME_08817	W2SMG9	W2TGK6	Vps51/Vps67.	DUF2451 domain-containing protein.	0.857
NECAME_01014	NECAME_08818	W2SMG9	W2TH97	Vps51/Vps67.	Vps54_N domain-containing protein.	0.857
NECAME_01014	NECAME_09540	W2SMG9	W2TCX0	Vps51/Vps67.	Vps52 / Sac2 family protein.	0.990
NECAME_01014	NECAME_09572	W2SMG9	W2TFU0	Vps51/Vps67.	Vps53-like protein.	0.995
NECAME_01431	NECAME_07710	W2TTY2	W2TP20	HMG box.	Runt domain protein.	0.641
NECAME_01536	NECAME_07286	W2TTI9	W2TRC1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Degenerin; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.422
NECAME_01536	NECAME_09012	W2TTI9	W2TF59	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Degenerin; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.422
NECAME_01536	NECAME_15020	W2TTI9	W2SJY9	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Collagen triple helix repeat protein.	0.557
NECAME_01536	NECAME_15062	W2TTI9	W2SJM2	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	EGF-like domain protein.	0.438
NECAME_01536	NECAME_19424	W2TTI9	W2SLI1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	DUF667 domain-containing protein.	0.686