(60 nodes) protein-DNA complex assembly network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_12290	Rod_C domain-containing protein. (415 aa)
	NECAME_04081	Uncharacterized protein. (659 aa)
	NECAME_03851	Uncharacterized protein. (220 aa)
	NECAME_04080	Uncharacterized protein. (163 aa)
	NECAME_13255	Transcription initiation factor TFIID subunit A. (293 aa)
	NECAME_18405	Uncharacterized protein. (116 aa)
	NECAME_04527	Uncharacterized protein. (142 aa)
	NECAME_19213	DUF3591 domain-containing protein. (144 aa)
	NECAME_12292	Uncharacterized protein. (228 aa)
	NECAME_03354	DUF3591 domain-containing protein. (483 aa)
	NECAME_03352	Bromodomain protein. (268 aa)
	NECAME_03554	Linker histone H1 and H5 family protein. (210 aa)
	NECAME_03353	Uncharacterized protein. (144 aa)
	NECAME_11697	Myb-like DNA-binding domain protein. (442 aa)
	NECAME_11676	Uncharacterized protein. (154 aa)
	NECAME_03078	Uncharacterized protein. (143 aa)
	NECAME_11398	Tetratricopeptide repeat protein. (356 aa)
	NECAME_03076	Uncharacterized protein. (134 aa)
	NECAME_03077	Uncharacterized protein. (95 aa)
	NECAME_10153	HTAFII28-like protein conserved region. (320 aa)
	NECAME_10158	Transcription initiation factor IID, subunit. (201 aa)
	NECAME_10421	Core histone H2A/H2B/H3/H4. (210 aa)
	NECAME_10390	CBFD_NFYB_HMF domain-containing protein. (165 aa)
	NECAME_04526	PHD-type domain-containing protein. (489 aa)
	NECAME_19177	Uncharacterized protein. (200 aa)
	NECAME_04636	Uncharacterized protein. (82 aa)
	NECAME_14242	Transcription factor TFIIB repeat-containing domain protein. (999 aa)
	NECAME_00878	Uncharacterized protein. (149 aa)
	NECAME_15110	Transcription initiation factor IIA, gamma subunit, helical domain protein. (155 aa)
	NECAME_15222	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (722 aa)
	NECAME_15876	Uncharacterized protein. (242 aa)
	NECAME_09380	Linker histone H1 and H5 family protein. (207 aa)
	NECAME_09198	Linker histone H1 and H5 family protein. (203 aa)
	NECAME_08781	Uncharacterized protein; Belongs to the RecA family. (333 aa)
	NECAME_02293	HEC/Ndc80p family protein. (587 aa)
	NECAME_00210	WD domain, G-beta repeat protein. (394 aa)
	NECAME_08303	Uncharacterized protein. (260 aa)
	NECAME_02061	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (342 aa)
	NECAME_07904	Linker histone H1 and H5 family protein. (180 aa)
	NECAME_01859	Linker histone H1 and H5 family protein. (186 aa)
	NECAME_07927	Nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. (281 aa)
	NECAME_07240	Meiotic recombinase Dmc1; Belongs to the RecA family. (345 aa)
	NECAME_01522	PHD-type domain-containing protein. (1097 aa)
	NECAME_06581	Transcription factor TFIIB repeat-containing domain protein. (270 aa)
	NECAME_16950	TAF6_C domain-containing protein. (361 aa)
	NECAME_16786	Core histone H2A/H2B/H3/H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (328 aa)
	NECAME_16529	TAFII55 protein conserved region. (229 aa)
	NECAME_06330	Uncharacterized protein. (395 aa)
	NECAME_05830	Uncharacterized protein. (376 aa)
	NECAME_06074	Uncharacterized protein. (115 aa)
	NECAME_01294	S-(Hydroxymethyl)glutathione synthase. (77 aa)
	NECAME_00094	Bromodomain associated. (137 aa)
	NECAME_00096	PHD-finger. (104 aa)
	NECAME_00150	Uncharacterized protein. (191 aa)
	NECAME_15875	Uncharacterized protein. (841 aa)
	NECAME_15654	Uncharacterized protein. (329 aa)
	NECAME_05611	Uncharacterized protein. (399 aa)
	NECAME_15846	Linker histone H1 and H5 family protein. (191 aa)
	NECAME_05612	Uncharacterized protein. (231 aa)
	NECAME_15970	Uncharacterized protein. (285 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00094	NECAME_00096	W2TYT4	W2U1M7	Bromodomain associated.	PHD-finger.	0.454
NECAME_00094	NECAME_03352	W2TYT4	W2T448	Bromodomain associated.	Bromodomain protein.	0.830
NECAME_00094	NECAME_03353	W2TYT4	W2T511	Bromodomain associated.	Uncharacterized protein.	0.830
NECAME_00094	NECAME_03354	W2TYT4	W2T3U4	Bromodomain associated.	DUF3591 domain-containing protein.	0.830
NECAME_00094	NECAME_06581	W2TYT4	W2TSQ0	Bromodomain associated.	Transcription factor TFIIB repeat-containing domain protein.	0.824
NECAME_00094	NECAME_10153	W2TYT4	W2T9T3	Bromodomain associated.	HTAFII28-like protein conserved region.	0.994
NECAME_00094	NECAME_10158	W2TYT4	W2T9T6	Bromodomain associated.	Transcription initiation factor IID, subunit.	0.936
NECAME_00094	NECAME_13255	W2TYT4	W2SYM9	Bromodomain associated.	Transcription initiation factor TFIID subunit A.	0.980
NECAME_00094	NECAME_15110	W2TYT4	W2SJN9	Bromodomain associated.	Transcription initiation factor IIA, gamma subunit, helical domain protein.	0.771
NECAME_00094	NECAME_16529	W2TYT4	W2TWG1	Bromodomain associated.	TAFII55 protein conserved region.	0.977
NECAME_00094	NECAME_16950	W2TYT4	W2TTA4	Bromodomain associated.	TAF6_C domain-containing protein.	0.873
NECAME_00094	NECAME_19213	W2TYT4	W2SS92	Bromodomain associated.	DUF3591 domain-containing protein.	0.830
NECAME_00096	NECAME_00094	W2U1M7	W2TYT4	PHD-finger.	Bromodomain associated.	0.454
NECAME_00096	NECAME_00150	W2U1M7	W2U1Q2	PHD-finger.	Uncharacterized protein.	0.417
NECAME_00096	NECAME_03352	W2U1M7	W2T448	PHD-finger.	Bromodomain protein.	0.981
NECAME_00096	NECAME_03353	W2U1M7	W2T511	PHD-finger.	Uncharacterized protein.	0.981
NECAME_00096	NECAME_03354	W2U1M7	W2T3U4	PHD-finger.	DUF3591 domain-containing protein.	0.981
NECAME_00096	NECAME_06330	W2U1M7	W2TX73	PHD-finger.	Uncharacterized protein.	0.795
NECAME_00096	NECAME_06581	W2U1M7	W2TSQ0	PHD-finger.	Transcription factor TFIIB repeat-containing domain protein.	0.981
NECAME_00096	NECAME_10153	W2U1M7	W2T9T3	PHD-finger.	HTAFII28-like protein conserved region.	0.996