(36 nodes) Plasma membrane signaling receptor complex network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_03641	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (210 aa)
	NECAME_11795	Ankyrin repeat protein. (466 aa)
	NECAME_03159	7 transmembrane receptor. (879 aa)
	NECAME_10725	Uncharacterized protein. (138 aa)
	NECAME_10590	Uncharacterized protein. (288 aa)
	NECAME_11033	Neur_chan_LBD domain-containing protein. (135 aa)
	NECAME_10591	Uncharacterized protein. (68 aa)
	NECAME_02838	7 transmembrane receptor. (761 aa)
	NECAME_07965	Receptor L domain protein. (880 aa)
	NECAME_01332	CUB domain protein. (355 aa)
	NECAME_01384	Uncharacterized protein. (325 aa)
	NECAME_06362	Uncharacterized protein. (232 aa)
	NECAME_07418	Uncharacterized protein. (168 aa)
	NECAME_07419	Uncharacterized protein. (96 aa)
	NECAME_15335	CUB domain protein. (253 aa)
	NECAME_15333	CUB domain protein. (141 aa)
	NECAME_14452	Uncharacterized protein. (208 aa)
	NECAME_14168	Uncharacterized protein. (90 aa)
	NECAME_14169	ANF_receptor domain-containing protein. (224 aa)
	NECAME_04417	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (300 aa)
	NECAME_13646	Uncharacterized protein. (363 aa)
	NECAME_04333	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
	NECAME_04418	Uncharacterized protein. (275 aa)
	NECAME_13308	Glutamate [NMDA] receptor subunit zeta-1 domain protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (598 aa)
	NECAME_04077	Uncharacterized protein. (280 aa)
	NECAME_12776	Uncharacterized protein. (246 aa)
	NECAME_04075	Integrin alpha. (650 aa)
	NECAME_04076	Uncharacterized protein. (167 aa)
	NECAME_02837	Uncharacterized protein. (108 aa)
	NECAME_10084	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (197 aa)
	NECAME_02515	FG-GAP repeat protein; Belongs to the integrin alpha chain family. (938 aa)
	NECAME_08807	Cation transporter family protein. (476 aa)
	NECAME_02164	Neur_chan_LBD domain-containing protein. (121 aa)
	NECAME_08712	Uncharacterized protein. (156 aa)
	NECAME_02162	Neurotransmitter-gated ion-channel transmembrane region; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (282 aa)
	NECAME_07964	Protein tyrosine kinase. (463 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_01332	NECAME_15333	W2TWZ9	W2SKX6	CUB domain protein.	CUB domain protein.	0.456
NECAME_01332	NECAME_15335	W2TWZ9	W2SIB0	CUB domain protein.	CUB domain protein.	0.456
NECAME_02162	NECAME_10084	W2TKF0	W2TB92	Neurotransmitter-gated ion-channel transmembrane region; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Neurotransmitter-gated ion-channel ligand binding domain protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.920
NECAME_02162	NECAME_11033	W2TKF0	W2T8C5	Neurotransmitter-gated ion-channel transmembrane region; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Neur_chan_LBD domain-containing protein.	0.481
NECAME_02515	NECAME_04075	W2TFR3	W2SZI6	FG-GAP repeat protein; Belongs to the integrin alpha chain family.	Integrin alpha.	0.466
NECAME_02837	NECAME_02838	W2TAS2	W2T9I4	Uncharacterized protein.	7 transmembrane receptor.	0.767
NECAME_02838	NECAME_02837	W2T9I4	W2TAS2	7 transmembrane receptor.	Uncharacterized protein.	0.767
NECAME_02838	NECAME_03159	W2T9I4	W2T655	7 transmembrane receptor.	7 transmembrane receptor.	0.955
NECAME_03159	NECAME_02838	W2T655	W2T9I4	7 transmembrane receptor.	7 transmembrane receptor.	0.955
NECAME_04075	NECAME_02515	W2SZI6	W2TFR3	Integrin alpha.	FG-GAP repeat protein; Belongs to the integrin alpha chain family.	0.466
NECAME_04075	NECAME_04076	W2SZI6	W2T0A5	Integrin alpha.	Uncharacterized protein.	0.829
NECAME_04075	NECAME_04077	W2SZI6	W2SXZ2	Integrin alpha.	Uncharacterized protein.	0.887
NECAME_04076	NECAME_04075	W2T0A5	W2SZI6	Uncharacterized protein.	Integrin alpha.	0.829
NECAME_04076	NECAME_04077	W2T0A5	W2SXZ2	Uncharacterized protein.	Uncharacterized protein.	0.900
NECAME_04077	NECAME_04075	W2SXZ2	W2SZI6	Uncharacterized protein.	Integrin alpha.	0.887
NECAME_04077	NECAME_04076	W2SXZ2	W2T0A5	Uncharacterized protein.	Uncharacterized protein.	0.900
NECAME_04333	NECAME_04417	W2SUP1	W2ST77	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.855
NECAME_04333	NECAME_04418	W2SUP1	W2SVJ3	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Uncharacterized protein.	0.841
NECAME_04417	NECAME_04333	W2ST77	W2SUP1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.855
NECAME_04417	NECAME_04418	W2ST77	W2SVJ3	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Uncharacterized protein.	0.839